Results 81 to 90 of about 101,100 (329)

Spatial Dispersal of Bacterial Colonies Induces a Dynamical Transition From Local to Global Quorum Sensing

, 2016
Bacteria communicate using external chemical signals called autoinducers (AI) in a process known as quorum sensing (QS). QS efficiency is reduced by both limitations of AI diffusion and potential interference from neighboring strains.
Boedicker, James Q., Yusufaly, Tahir I.
core   +1 more source

Carbon‐Based Flexible Electrode for Efficient Electrochemical Generation of Reactive Chlorine Species in Tumor Therapy

Advanced Healthcare Materials, EarlyView.
A flexible electrode loaded with a carbon nanowire network (CC@C‐NWN) is developed for electrochemically generating reactive chlorine species (RCS) from abundant chloride ions in body fluids for tumor therapy. CC@C‐NWN enhances chlorine evolution, inducing redox dysregulation and synergistic apoptosis‐ferroptosis in tumor cells.
Cuinan Jiang, Zhaoyu Chen, Ruihao Yang, Ziga Luogu, Qian Ren, Hao Hu, Kaixin Wang, Senlin Li, Changlin Deng, Meng Li, Lu Zheng   +10 more
wiley   +1 more source

Microfluidic study of the chemotactic response of Escherichia coli to amino acids, signaling molecules and secondary metabolites [PDF]

, 2015
Quorum sensing and chemotaxis both affect bacterial behavior on the population level. Chemotaxis shapes the spatial distribution of cells, while quorum sensing realizes a cell-density dependent gene regulation.
Galajda, Péter, Gombai, É., Hodula, O., Kerényi, Ádám, Nagy, Krisztina, Ormos, Pál, Sipos, Orsolya, Valkai, Sándor   +7 more
core   +1 more source

Peptide Display Directed Assembly of Biopolymer Core–Silica Shell Particles

Advanced Healthcare Materials, EarlyView.
Bacterial cells are engineered to produce biopolyester particles displaying peptides mediating growth of silica. Peptide‐coated biopolyester particles are treated with silica precursors and silica shell formation is studied. Transmission electron microscopy shows silica‐coated BPs which are formed after the silicification treatment. Characterization of
Deeptee Chandrashekhar Pande, Frank Sainsbury, Bernd H. A. Rehm   +2 more
wiley   +1 more source

Social Evolution Selects for Redundancy in Bacterial Quorum Sensing.

PLoS Biology, 2016
Quorum sensing is a process of chemical communication that bacteria use to monitor cell density and coordinate cooperative behaviors. Quorum sensing relies on extracellular signal molecules and cognate receptor pairs. While a single quorum-sensing system
Eran Even-Tov, Shira Omer Bendori, Julie Valastyan, Xiaobo Ke, Shaul Pollak, Tasneem Bareia, Ishay Ben-Zion, Bonnie L Bassler, Avigdor Eldar   +8 more
doaj   +1 more source

Bacteria clustering by polymers induces the expression of quorum sense controlled phenotypes [PDF]

, 2013
Bacteria deploy a range of chemistries to regulate their behaviour and respond to their environment. Quorum sensing is one mean by which bacteria use chemical reactions to modulate pre-infection behaviour such as surface attachment.
A Camilli, AB Goryachev, AC Engler, AE Clatworthy, AK Epstein, AL Garner, AL Hook, Alan Brown, AML Barnard, C Alexander, C Fuqua, C Nathan, CA Lowery, Cameron Alexander, Cheng Sui, CJ Kastrup, D-W Lee, DA Bricarello, David I. Pritchard, E-R Kenawy, EC Carnes, EC Pesci, EV Piletska, F Nederberg, Francisco Fernandez-Trillo, GF Kaufmann, J Park, J Shepherd, JP Pearson, JQ Boedicker, K Bush, Klaus Winzer, L Liu, LCM Antunes, Leong T. Lui, MB Miller, MJ Federle, MK Winson, MK Winson, N Krasnogor, Natalio Krasnogor, Nigel Halliday, P Cossart, P Klemm, P Rai, P Wei, P Williams, P Williams, PC Fineran, REW Hancock, REW Hancock, RJ Redfield, RS Smith, S Alberghini, S Atkinson, S Swift, SP Diggle, ST Flickinger, Steven M. Howdle, X Xue, Xuan Xue   +60 more
core   +3 more sources

High‐Resolution Patterned Delivery of Chemical Signals From 3D‐Printed Picoliter Droplet Networks

Advanced Materials, EarlyView.
3D‐printed picoliter droplet networks have been fabricated that control gene expression in bacterial populations by releasing chemical signals with precise spatial definition and high temporal resolution. This system of effector release is widely applicable, offering diverse applications in biology and medicine.
Jorin Riexinger, Thomas Caganek, Xingzao Wang, Yutong Yin, Khoa Chung, Linna Zhou, Hagan Bayley, Ravinash Krishna Kumar   +7 more
wiley   +1 more source

Preclinical common data elements for general pharmacological studies (pharmacokinetic sample collection, tolerability, and drug administration). A report of the TASK3‐WG1A General Pharmacology Working Group of the ILAE/AES Joint Translational Task Force

Epilepsia Open, EarlyView., 2023
Abstract Growing concerns over rigor and reproducibility of preclinical studies, including consistency across laboratories and translation to clinical populations, have triggered efforts to harmonize methodologies. This includes the first set of preclinical common data elements (CDEs) for epilepsy research studies, as well as Case Report Forms (CRFs ...
Lisa Coles, Patrick A. Forcelli, Karine Leclercq, Anna‐Maria Katsarou, Brian D. Klein, Heidrun Potschka, Rudiger Koehling, Lauren Harte‐Hargrove, Aristea S. Galanopoulou, Cameron S. Metcalf   +9 more
wiley   +1 more source

Reversible Signal Binding by the Pseudomonas aeruginosa Quorum-Sensing Signal Receptor LasR

mBio, 2011
Many members of the LuxR family of acyl-homoserine lactone (acyl-HSL)-dependent quorum-sensing transcriptional activators are thought to have the unusual characteristics of requiring the signal ligand during polypeptide synthesis to fold into an active ...
Kaia J. Sappington, Ajai A. Dandekar, Ken-Ichi Oinuma, E. Peter Greenberg   +3 more
doaj   +1 more source

Supramolecular Conductive Hydrogels With Homogeneous Ionic and Electronic Transport

Advanced Materials, EarlyView.
Poly(3,4‐ethylenedioxythiophene) polystyrene sulfonate (PEDOT:PSS) based conductive hydrogels have received great attention in bioelectronics on account of their tissue‐like mechanical properties. However, inhomogeneous morphologies of the conducting PEDOT phase limits their electrical and mechanical properties. Here, supramolecular hydrogels with self‐
Stephen J.K. O'Neill, Minoru Ashizawa, Alan M. McLean, Ruben Ruiz‐Mateos Serrano, Tokihiko Shimura, Masakazu Agetsuma, Motosuke Tsutsumi, Tomomi Nemoto, Christopher D. J. Parmenter, Jade A. McCune, George G. Malliaras, Naoji Matsuhisa, Oren A. Scherman   +12 more
wiley   +1 more source