Results 81 to 90 of about 2,481,764 (342)

Recent Advances in Anti-virulence Therapeutic Strategies With a Focus on Dismantling Bacterial Membrane Microdomains, Toxin Neutralization, Quorum-Sensing Interference and Biofilm Inhibition

open access: yesFrontiers in Cellular and Infection Microbiology, 2019
Antimicrobial resistance constitutes one of the major challenges facing humanity in the Twenty-First century. The spread of resistant pathogens has been such that the possibility of returning to a pre-antibiotic era is real.
Osmel Fleitas Martínez   +3 more
semanticscholar   +1 more source

Antimicrobial Efficacy of a Taurolidine‐Based Antimicrobial Compound on Contaminated Surfaces Simulated in a Standardized 4‐Field Test

open access: yesAdvanced Healthcare Materials, EarlyView.
As implantable medical devices become indispensable to modern medicine, a silent threat grows alongside them: device‐associated infections. Despite decades of antibiotic innovation, infection rates keep climbing, costing lives and billions in healthcare expenses.
Benito Baldauf   +5 more
wiley   +1 more source

Quorum sensing in biofilm-mediated heavy metal resistance and transformation: environmental perspectives and bioremediation

open access: yesFrontiers in Microbiology
Quorum sensing is a fundamental mechanism of bacterial cell-to-cell communication that enables microbial communities to adapt to environmental stresses. Although the role of quorum sensing in biofilm formation and heavy metal resistance has been studied ...
Subhoshmita Mondal   +3 more
doaj   +1 more source

A Biomimetic Buffering Hydrogel Scaffold for Long‐Term Culture of Patient‐Derived Tumor Organoids

open access: yesAdvanced Healthcare Materials, EarlyView.
A biomimetic fibrous buffering hydrogel controls the local acidification at the tumoroid/hydrogel interface at the physiologically relevant level over 21‐day culture. The buffering effect promotes cancer cell proliferation in the tumoroids and supports the structural integrity and mechanical properties of the hydrogel scaffold over long‐term tumoroid ...
Elizaveta Gusarova   +5 more
wiley   +1 more source

SnapShot: Bacterial Quorum Sensing

open access: yesCell, 2018
Quorum sensing (QS) is a chemical communication process that bacteria use to orchestrate group behaviors. QS involves the production, release, and population-wide detection of signaling molecules called autoinducers. QS-controlled behaviors are unproductive when undertaken by a single bacterium but become effective when performed by the group.
Michaela J, Eickhoff, Bonnie L, Bassler
openaire   +2 more sources

Biofilm‐Antagonist Ginger‐Based 3D‐Printable Photoresins for Complex Implant Designs Exhibiting Advanced Multifunctional Biomedical Applications

open access: yesAdvanced Materials, EarlyView.
This work offers unique Ginger‐based 3D‐printable resins that can print customizable high‐resolution complex designs. The customizable printing backbone of Zingerol prints also mimics various human bones' strength. Acquisition of in‐vivo biocompatibility in rat model with no severe inflammatory response, along with in‐vitro antioxidant and ex‐vivo anti‐
Simran Jindal   +9 more
wiley   +1 more source

The Potential of Secondary Metabolites in Medicinal Plants as Anti–Quorum Sensing in Biofilms: A Comprehensive Review

open access: yesJournal of Chemistry
The formation of biofilms occurs due to a group of bacteria gathering together. The increasing of cell density will stimulate chemical signals for bacteria to communicate through quorum sensing system.
Salsabila Aqila Putri   +3 more
doaj   +1 more source

Quorum sensing with pheromones [PDF]

open access: yesNature Microbiology, 2019
The vast majority of fungi reproduce sexually and use secreted pheromones to signal to each other. A study now shows that these signalling molecules in the fungal plant pathogen Fusarium oxysporum activate a density-dependent autocrine signal that controls asexual spore germination.
openaire   +3 more sources

Bacteria‐Responsive Nanostructured Drug Delivery Systems for Targeted Antimicrobial Therapy

open access: yesAdvanced Materials, EarlyView.
Bacteria‐responsive nanocarriers are designed to release antimicrobials only in the presence of infection‐specific cues. This selective activation ensures drug release precisely at the site of infection, avoiding premature or indiscriminate release, and enhancing efficacy.
Guillermo Landa   +3 more
wiley   +1 more source

Reversible Signal Binding by the Pseudomonas aeruginosa Quorum-Sensing Signal Receptor LasR

open access: yesmBio, 2011
Many members of the LuxR family of acyl-homoserine lactone (acyl-HSL)-dependent quorum-sensing transcriptional activators are thought to have the unusual characteristics of requiring the signal ligand during polypeptide synthesis to fold into an active ...
Kaia J. Sappington   +3 more
doaj   +1 more source

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