Results 141 to 150 of about 16,571 (204)

Annexin A6 modulates TBC1D15/Rab7/StARD3 axis to control endosomal cholesterol export in NPC1 cells.

Cholesterol accumulation in late endosomes is a prevailing phenotype of Niemann-Pick type C1 (NPC1) mutant cells. Likewise, annexin A6 (AnxA6) overexpression induces a phenotype reminiscent of NPC1 mutant cells.
Enrich Bastús, Carles, Meneses Salas, Elsa, Tebar Ramon, Francesc, García Melero, Ana, Morales Paytuvi, Frederic, Jose, Jaimy, Beevi, Syed S., Rentero Alfonso, Carles, Blanco Muñoz, Patricia, Casas Brugulat, Josefina, Kanerva, Kristiina, Grewal, Thomas, Bonjoch, Júlia, Rye, Kerry-Anne, Pol i Sorolla, Albert, Ikonen, Elina, Lu, Albert, Egert, Antonia, Heeren, Joerg, Llorente Cortés, Vicenta   +19 more
core  

Interference of Large Clostridial Glucosyltransferases with the Endolysosomal Pathway: Toxin-Induced Imbalance of Early Endosomes, Functional Lysosomes and Autophagosomes. [PDF]

Toxins (Basel)
Langejürgen A, Schmidt G, Unsöld L, Tatge H, Oyson E, Gerhard R.   +5 more
europepmc   +1 more source

PIKfyve is required for efficient phagosomal Rab7 acquisition and the delivery and fusion of early macropinosomes to phagosomes. [PDF]

J Cell Sci
Vines JH, Buckley CM, Willson I, Stark DS, King JS.   +4 more
europepmc   +1 more source

Pathogenic <i>LRSAM1</i> RING Domain Variants Disrupt Intracellular Protein Localization in Charcot-Marie-Tooth Disease Type 2P. [PDF]

Hum Mutat
Hakonen JE, Hellings TP, Dingemanse E, Laman B, Froncek OJ, NynkeWienholts, Lamzira-Arichi N, van den Berg M, Baas F, Zelcer N, Weterman MAJ.   +10 more
europepmc   +1 more source

FcγRIIA signalling as a host-associated determinant of endosomal trafficking and antibody-dependent enhancement in flavivirus infection. [PDF]

Front Immunol
Rakwi NWWP, Muraoka D, Haga K, Yeo ASL, Moi ML.   +4 more
europepmc   +1 more source

A novel rapid host cell entry pathway determines the intracellular fate of <i>Staphylococcus aureus</i>. [PDF]

Elife
Rühling M, Schmelz F, Ulbrich K, Schumacher F, Wolf J, Pfefferle M, Priester M, Moldovan A, Knoch N, Iwanowitsch A, Kappe C, Paprotka K, Kleuser B, Arenz C, Fraunholz MJ.   +14 more
europepmc   +1 more source

Membrane lipid composition and rapid endocytic retrieval modulate Wingless secretion. [PDF]

EMBO J
Alvarez-Rodrigo I, Willnow D, Alexandre C, Lebarbenchon C, Borg A, Findlay H, Hoad Leftley M, Arahouan I, Zhao Y, di Pietro F, Kjaer S, Booth P, Bauer R, Jones EY, Bellaïche Y, Vincent JP.   +15 more
europepmc   +1 more source

Molecular and biophysical requirements for B cell receptor-dependent enhancement of dengue virus infection. [PDF]

J Virol
Madrigal G, Gebo C, McElvany BD, Symeonides M, Diehl SA, Waickman AT.   +5 more
europepmc   +1 more source

The nuclear receptor ESRRA is a crucial regulator of acute kidney injury through inhibition of the lipophagy-ferroptosis axis. [PDF]

Autophagy
Yang Y, Zhu X, Fang Y, Li J, Shao X, Li S, Jin H, Qi C, Li Z, Gu L, Mou S, Lin Q, Ni Z.   +12 more
europepmc   +1 more source