Phagosomes containing M. tuberculosis and M. bovis BCG interact normally with early endosomes but fail to fuse with late endosomes and lysosomes. Whereas many early events of mycobacterial phagosomes have been elucidated, the exact mechanism of the ...
SOUALHINE H +6 more
core
The endo-lysosomal system drives lumen formation in a human epiblast model. [PDF]
Rengarajan A +10 more
europepmc +1 more source
VPS35 Regulates Microglial Lipid Droplet Accumulation in Parkinson's Disease via Rab7. [PDF]
Liang Y +7 more
europepmc +1 more source
Semliki forest virus (SFV) is internalized by clathrin-mediated endocytosis, and transported via early endosomes to late endosomes and lysosomes. The intracellular pathway taken by individual fluorescently labeled SFV particles was followed using ...
doaj +1 more source
Rab GTPases drive ligand-independent NOTCH1 activation via altered endocytic trafficking in chronic lymphocytic leukemia. [PDF]
De Falco F +17 more
europepmc +1 more source
Bisphosphonate zoledronic acid blocks secretory autophagy and inhibits bone resorptive functions in osteoclasts. [PDF]
Kim S +7 more
europepmc +1 more source
Regulation of NOT CH signaling by RAB7 and RAB8 requires carboxyl methylation by ICMT
Isoprenylcysteine carboxyl methyltransferase (ICMT) methylesterifies C-terminal prenylcysteine residues of CaaX proteins and some RAB GTPases. Deficiency of either ICMT or NOTCH1 accelerates pancreatic neoplasia in Pdx1-Cre;LSL-KrasG12D mice, suggesting ...
Amoyel, M +4 more
core
Dietary Arthrospira platensis modulates autophagy-related markers in breast muscle of heat-stressed broilers and chicken primary myoblasts. [PDF]
Liu L, Greene ES, Dridi S.
europepmc +1 more source
FIS1 dependent peripheral fission exacerbates mitochondrial fragmentation and dysfunction in prion diseases. [PDF]
Gou F +12 more
europepmc +1 more source

