Results 21 to 30 of about 78,155 (186)

Specific Rab GTPase-activating proteins define the Shiga toxin and epidermal growth factor uptake pathways [PDF]

, 2007
Rab family guanosine triphosphatases (GTPases) together with their regulators define specific pathways of membrane traffic within eukaryotic cells. In this study, we have investigated which Rab GTPase-activating proteins (GAPs) can interfere with the ...
Evelyn Fuchs, Francis A. Barr, Spooner, Robert A., Robert A. Spooner, Shin-ichiro Yoshimura, Hass, Alexander K., Fuchs, Evelyn, Lord, Mike, Haas, Alexander K., J. Michael Lord, Alexander K. Haas, Yoshimura, Shin-ichiro, Barr, Francis A.   +12 more
core   +1 more source

Imaging of Spatial Cycling of Rab GTPase in the Cell

, 2021
Rab GTPases (>60 members in human) function as master regulators of intracellular membrane trafficking. To fulfill their functions, Rab proteins need to localize on specific membranes in cells.
Wu, Yao-Wen,, Yao-Wen Wu, Fu Li, Li, Fu,
core   +1 more source

RAB21 Activity Assay Using GST-fused APPL1

Bio-Protocol, 2016
The Rab family of small GTPases are essential regulators of membrane trafficking events. As with other small GTPase families, Rab GTPases cycle between an inactive GDP- bound state and an active GTP-bound state. Guanine nucleotide exchange factors (GEFs)
Steve Jean, Amy Kiger
doaj   +1 more source

Biogenesis of the inner membrane complex is dependent on vesicular transport by the alveolate specific GTPase Rab11B [PDF]

, 2010
Apicomplexan parasites belong to a recently recognised group of protozoa referred to as Alveolata. These protists contain membranous sacs (alveoli) beneath the plasma membrane, termed the Inner Membrane Complex (IMC) in the case of Apicomplexa.
Bernardo J. Foth, Ferguson, D.J. P., Markus Meissner, David J. P. Ferguson, Foth, B.J., Carolina Agop-Nersesian, Langsley, G., Saskia Egarter, Meissner, M., Egarter, S., Sibley, L.D., Bernardo J Foth, Gordon Langsley, Agop-Nersesian, C., David J P Ferguson, Foth Bernardo J., Meissner Markus, Agop-Nersesian Carolina, Egarter Saskia, Langsley Gordon, Ferguson David J. P.   +20 more
core   +1 more source

The Emerging Role of Rab5 in Membrane Receptor Trafficking and Signaling Pathways

Biochemistry Research International, 2020
Ras analog in brain (Rab) proteins are small guanosine triphosphatases (GTPases) that belong to the Ras-like GTPase superfamily, and they can regulate vesicle trafficking.
Wanqiong Yuan, Chunli Song
doaj   +1 more source

C9orf72 Plays a Central Role in Rab GTPase-Dependent Regulation of Autophagy [PDF]

Small GTPases, 2018
Andrew Grierson, Kurt J De Vos, Christopher P Webster   +2 more
exaly   +2 more sources

Adrenergic Contraction of Human Prostate Tissues Is Maintained Under the Rab GTPase Inhibitors Nexhinib20 and CID1067700 [PDF]

Pharmacol Res Perspect
ABSTRACT α1‐Adrenoceptors are an important drug target in benign prostatic hyperplasia (BPH) and have been intensively studied at the expression level, but their posttranslational regulation in the prostate is widely unknown. Here we examined modulation of prostate smooth muscle contractions by inhibitors for RabGTPases, which are involved in ...
Troffer L, Cen P, Brandstetter M, Xu Y, Keller P, Stadelmeier L, Weinhold P, Tamalunas A, Stief C, Hennenberg M.   +9 more
europepmc   +2 more sources

A RabGAP-Rab GTPase pair regulates plant autophagy and immunity - Alphafold2-multimer data

, 2023
This data set was used in the publication "A RabGAP-Rab GTPase pair regulates plant autophagy and immunity". These are AF2-multimer prediction folders that were generated by AF2.
Enoch Lok Him Yuen (16455333)
core   +1 more source

Role of Rab GTPases in Hepatocellular Carcinoma

Journal of Hepatocellular Carcinoma, 2021
Chun-Cheng Yang,1,* Guang-Xiao Meng,1,* Zhao-Ru Dong,1,* Tao Li1,2 1Department of General Surgery, Qilu Hospital, Shandong University, Jinan, People’s Republic of China; 2Department of Hepatobiliary Surgery, The Second Hospital of Shandong ...
Yang CC, Meng GX, Dong ZR, Li T
doaj  

Construction of a Plasmodium falciparum Rab-interactome identifies CK1 and PKA as Rab-effector kinases in malaria parasites [PDF]

, 2011
Background information The pathology causing stages of the human malaria parasite Plasmodium falciparum reside within red blood cells that are devoid of any regulated transport system.
Tatu, Utpal, Yera, H., Yera, Helene, Talabani, Hana, Talabani, H., Dandavate, V., Dandavate, Vrushali, Langsley, Gordon, Tatu, U., Langsley, G., Bourdoncle, P., Meissner, M., Ben Rached, Fathia, Ndjembo-Ezougou, Carinne, Rached, F.B., Chandran, S., Chandran, Syama, Ndjembo-Ezougou, C., Bourdoncle, Pierre, Meissner, Markus   +19 more
core   +1 more source