Results 91 to 100 of about 20,263 (191)

Rabbit hemorrhagic disease (RHD): characterization of the causative calicivirus.

Veterinary research, 1993
Rabbit hemorrhagic disease (RHD) which was first recognized in China in 1984 spread via Eastern Europe to many countries of Western Europe and other parts of the world. The analysis of the virus outlined in this review comprises: 1) physico-chemical properties, 2) electron microscopy including immunoelectron microscopy, 3) demonstration of capsid ...
Ohlinger, Vf, Haas, B, Thiel, Hj
openaire   +2 more sources

Graded traumatic brain injury severity differentially modulates microglial and astrocytic polarization states and response to minocycline

Neuroprotection, EarlyView.
Schematic diagram of the experimental design and key findings of traumatic brain injury (TBI) with varying severities. Mild, moderate, and severe TBI were induced in the right motor cortex of mice using the controlled cortical impact (CCI) method, with impact depths of 0.5, 1.0, and 2.0 mm, respectively. A subset of severe TBI mice received minocycline
Yan Yu, Chen Wang, Jinyu Zhu, Jiahui Du, Hao Li, Shuyi Ning, Rui Yang, Yiwen Ma, Mengyuan Yuan, Wei Shen, Huailin Wang, Huihui Jiang, Liping Chen, Haitao Wu   +13 more
wiley   +1 more source

Independent Risk Factors for Postoperative Intestinal Obstruction and Clinical Outcomes in Simultaneous Pancreas‐Kidney Transplantation Recipients

Organ Medicine, EarlyView.
Intestinal obstruction (IO) is an important but underexplored complication following simultaneous pancreas‐kidney transplantation (SPKT) and is associated with considerable morbidity and both clinical and economic burdens. In this single‐center cohort study, perioperative parameters, including demographic characteristics, surgical variables, and ...
Rongxin Chen, Zebin Guo, Guanghui Li, Jiali Fang, Jialin Wu, Zhuangqiang Fang, Luhao Liu, Zheng Chen   +7 more
wiley   +1 more source

Long‐term outcomes of haploidentical hematopoietic stem cell transplantation with antithymocyte globulin–based myeloablative conditioning in pediatric refractory or relapsed non‐Hodgkin lymphoma

Pediatric Investigation, EarlyView.
Single‐center retrospective data showed that ATG‐based myeloablative haploidentical hematopoietic stem cell transplantation provides durable remission and favorable long‐term survival in children with refractory/relapsed non‐Hodgkin lymphoma, achieving high engraftment rates, low relapse incidence, and acceptable toxicity.
Chenguang Jia, Jie Zheng, Meng Yuan, Hongbo He, Yibo Fan, Bin Wang, Guanghua Zhu, Jun Yang, Yanhui Luo, Lixiao Cai, Pan Zhang, Yanlong Duan, Maoquan Qin   +12 more
wiley   +1 more source

Inhibition of interferon signaling improves rabbit calicivirus replication in biliary organoid cultures

Journal of Virology
The Rabbit hemorrhagic disease virus (RHDV) was discovered 40 years ago. This highly pathogenic virus threatens the integrity of ecosystems in the European rabbit’s native range, while in Australia, it is used as a biocontrol tool to manage overabundant ...
Elena Smertina, Megan Pavy, Nias Y. G. Peng, Omid Fahri, Maria Jenckel, Tanja Strive, Michael Frese, Ina L. Smith   +7 more
doaj   +1 more source

Small‐Scale Magnetic Soft Robots for Medical Applications: From Laboratory to Clinical Use

SmartBot, EarlyView.
Small‐scale magnetic soft robots are emerging as promising platforms for minimally invasive diagnosis and therapy in complex in vivo environments. This review compares untethered and tethered medical magnetic robots in parallel across five translational stages, from basic performance testing to clinical evaluation.
Xingxing Ke, Shizhi Li, Tianrui Zhang, Yue Zhong, Songyang Li, Shuo Zhang, Zhiping Chai, Menghao Pu, Zisheng Zong, Haochen Yong, Xingxing Dong, Lanting Huang, Zhen Deng, Shuaizheng Yan, Yue Zhang, Zhaoju Zhu, Mingzhu Zhu, Linze Li, Ruiquan Chen, Shu Zhang, Chong Wu, Di Wu, Lei Yang, Rui Chen, Tongzhi Niu, Hongling Qin, Han Ding, Bingwei He, Siqi Wu, Zhigang Wu   +29 more
wiley   +1 more source

Sphinganine‐phosphate prevents influenza infection via promoting CD8+ T cells proliferation and activation

VIEW, EarlyView.
This study established clinical cohorts of respiratory viral infections and identified sphinganine‐phosphate (SA) as a metabolite significantly upregulated post‐infection through metabolomic analysis. In vitro and in vivo experiments demonstrated that SA promotes the generation of effector CD8+ T cells via the SOCS1/JAK1/STAT1 pathway, which ...
Zhongwen Hu, Guiling Yan, Junhong Li, Yuan Yuan, Hong Zhang, Yuchao Zhong, Yuanyuan Peng, Wenjia Zhang, Xiaoyan Su, Changchun Niu, Yang Luo   +10 more
wiley   +1 more source

First Detection of Benign Rabbit Caliciviruses in Chile

Viruses
Pathogenic lagoviruses (Rabbit hemorrhagic disease virus, RHDV) are widely spread across the world and are used in Australia and New Zealand to control populations of feral European rabbits.
Elena Smertina, Luca M. Keller, Nina Huang, Gabriela Flores-Benner, Jennifer Paola Correa-Cuadros, Melanie Duclos, Fabian M. Jaksic, Cristóbal Briceño, Victor Neira Ramirez, Miguel Díaz-Gacitúa, Sebastián Carrasco-Fernández, Ina L. Smith, Tanja Strive, Maria Jenckel   +13 more
doaj   +1 more source

Extinction Debt Paid Off: The Demise of the European Polecat (Mustela putorius) in NE Iberia

Integrative Zoology, EarlyView.
We studied a vanishing polecat population for a decade, until its ultimate demise, using camera trap and roadkill data, landscape descriptors and dietary and toxicological analyses.Polecat favoured farmland and avoided forests and water bodies occupied by the invasive American mink.
Salvador Salvador, Roger Puig‐Gironès, Xavier Llopart, Santiago Palazón, Miguel Clavero   +4 more
wiley   +1 more source

Myeloablative Busulfan, Fludarabine and Melphalan Conditioning for Allogeneic Hematopoietic Stem Cell Transplantation in Childhood Myeloid Malignancy

Asia-Pacific Journal of Clinical Oncology, EarlyView.
We report our single‐center experience of transplant outcomes with a busulfan, fludarabine and melphalan‐based conditioning regimen for children < 18 years of age. The regimen was shown to be well tolerated and effective for heavily pretreated children with high‐risk myeloid malignancies prior to allogeneic hematopoietic stem cell transplant.
Mayank Dhamija, Fiona Kerr, Hazel Gough, Johnathan Soggee, Laurence C. Cheung, Rishi S. Kotecha, Shanti Ramachandran   +6 more
wiley   +1 more source