Results 41 to 50 of about 5,941 (192)

Third Space Endoscopic Therapies for Benign Motility Disorders: A Narrative Review

DEN Open, Volume 7, Issue 1, April 2027.
ABSTRACT Objectives To review the evidence base, evolution, outcomes, adverse events (AEs), and management for third‐space endoscopy (TSE) procedures for management of benign motility disorders. Methods This review examines TSE procedures for motility disorders, reviewing the current available techniques, success, outcomes, and long‐term outcomes from ...
Sanjana Bhagwat, Amol Bapaye
wiley   +1 more source

Comparative Efficacy of Rabeprazole and Pantoprazole in the Control of Nocturnal Acid Output and Intragastric Acidity

Gut and Liver, 2008
Background/Aims: Nocturnal reflux is a largely undiagnosed and unmanaged condition predisposing to multiple esophageal complications. We evaluated the effects of rabeprazole and pantoprazole on nocturnal intragastric pH and gastric acid output during Day
doaj   +1 more source

Functional diseases of the gastrointestinal tract in the context with overlapping functional disorders: current status of the problem [PDF]

Терапевтический архив, 2020
Functional diseases of the gastrointestinal tract cause significant damage to the health care system. Their frequent combination in the same patient with the migration of clinical symptoms throughout the digestive tube is accompanied by continuous ...
M. A. Osadchuk, A. A. Svistunov, N. V. Kireeva, M. M. Osadchuk   +3 more
doaj   +1 more source

Miliary Tuberculosis Diagnosed After Repeated Sputum Smear Examinations Despite Negative Results at a Referral Tuberculosis Center: The Importance of Maintaining Clinical Suspicion

Journal of General and Family Medicine, Volume 27, Issue 5, September 2026.
ABSTRACT An 88‐year‐old woman with back pain was found to have destructive changes at T9/T10 and diffuse micronodular pulmonary opacities suggestive of miliary tuberculosis. At two referring hospitals, six sputum smears and two interferon‐gamma release assays were negative.
Kento Kabeya, Kousuke Mouri, Hidehiro Someko   +2 more
wiley   +1 more source

Gastroesophageal Reflux Disease Relief in Patients Treated with Rabeprazole 20 mg versus Omeprazole 20 mg: A Meta-Analysis

Gastroenterology Research and Practice, 2013
Background. Randomized controlled trials (RCTs) have been conducted comparing the efficacy of rabeprazole 20 mg or omeprazole 20 mg once daily for patients with erosive gastroesophageal reflux disease (GERD).
X. M. Xia, H. Wang
doaj   +1 more source

The influence of CYP2C19 polymorphism on the effectiveness of the treatment of acid-dependent diseases

Медицинский совет, 2022
Introduction. In modern systematic reviews, there is a point of view that CYP2C19 polymorphism affects the results of treatment of peptic ulcer, erosive esophagitis and eradication of Helicobacter pylori.Оbjective.
V. V. Tsukanov, A. V. Vasyutin, Ju. L. Tonkikh, M. V. Smolnikova, M. A. Cherepnin, N. A. Maslennikova, N. V. Pavlova   +6 more
doaj   +1 more source

A Practical Alternative to Refine the Estimate of fmCYP3A4 and Evaluate Drug–Drug Interaction Potential for Ziftomenib Using PBPK Modeling to Inform Labeling

CPT: Pharmacometrics &Systems Pharmacology, Volume 15, Issue 9, September 2026.
ABSTRACT Accurate physiologically based pharmacokinetic (PBPK) simulation of drug–drug interaction (DDI) potential requires estimation of the relative contribution of the impacted pathway. While fraction metabolized by CYP enzymes is usually estimated using dedicated clinical DDI studies with strong CYP inhibitors, this approach might not be available ...
Ian E. Templeton, Chara Litou, Hannah M. Jones, Julie Mackey Ahsan, Marilyn Tabachri, Mollie Leoni, Amitava Mitra   +6 more
wiley   +1 more source

Effects of rabeprazole on early symptom relief in gastro-oesophageal reflux disease: the Hellenic Rabeprazole Study Group surveillance study

, 2005
Background: In controlled clinical trials, rabeprazole effectively improves symptoms and heals oesophageal erosions in patients with gastro-oesophageal reflux disease (GORD).
Kouklakis, G, Tsianos, E, E, Rabeprazole Study Grp, Hellenic, Archimandritis, AJ, Avgerinos, A, Nikolopoulou, V, Triantafillidis, JK, Paraskevas   +9 more
core   +1 more source

Penetrating Chest Trauma With Lung Evisceration, Pneumomediastinum, Pneumocranium, and Brachial Plexus Injury: A Case Report From a Resource‐Limited Setting

Clinical Case Reports, Volume 14, Issue 8, August 2026.
ABSTRACT High‐energy open chest injuries with lung evisceration may be associated with concurrent injuries and serious potential sequelae including pneumocranium, brachial plexus injury, and venous thrombosis. Early resuscitation, adherence to ATLS principles, and coordinated multidisciplinary care are critical for survival and functional outcomes ...
Brian Kasagga, Jamal‐diin Lubega Wamala, Dan Otim, Ketra Venessa Nandera, Godfrey Kikuba, Dan Ssekiwunga, Paul Ssempebwa, John Paul Magala, Emmanuel Elobu, Wilberforce Kabweru, Rachel Koch   +10 more
wiley   +1 more source

Stereoselective Biotransformation: Transfer of Learning to Advance Drug Metabolism and Biocatalysis

Angewandte Chemie, Volume 138, Issue 25, 15 June 2026.
Understanding stereoselective biotransformations has implications for predicting drug disposition and response and may also inspire novel biocatalytic and biomimetic strategies to address challenges in metabolite and API synthesis. ABSTRACT Chirality is an important determinant of drug action, as enantiomers can exhibit markedly different ...
Grace A. Okunlola, Godwin A. Aleku
wiley   +2 more sources