Results 21 to 30 of about 8,454 (202)

Comparison of the effectiveness of rabeprazole original and generic products in the monotherapy of gastroesophageal reflux disease

Терапевтический архив, 2023
Aim. To compare the effectiveness of rabeprazole original and generic products in the treatment of gastroesophageal reflux disease (GERD) using impedance-pH monitoring. Materials and methods.
Oksana V. Krapivnaia
doaj   +1 more source

Head-to-head comparison of H2-receptor antagonists and proton pump inhibitors in the treatment of erosive esophagitis: A meta-analysis [PDF]

, 2005
Aim: To systematically evaluate the efficacy of H2-receptor antagonists (H2RAs) and proton pump inhibitors in healing erosive esophagitis (EE). Methods: A meta-analysis was performed.
Huang, JQ, Lam, SK, Wang, WH, Wong, BCY, Wong, WM, Xia, HHX, Zheng, GF   +6 more
core   +1 more source

Mucosal Healing Effectiveness and Safety of Anaprazole, a Novel PPI, vs. Rabeprazole in Patients With Duodenal Ulcers: A Randomized Double-Blinded Multicenter Phase II Clinical Trial

Frontiers in Medicine, 2021
Background: Proton pump inhibitors (PPIs) are validated gastric acid suppressors and have been widely used to treat patients with active duodenal ulcers.
Xu Shu, Zhenhua Zhu, Yu Fu, Zhenyu Zhang, Jiangbin Wang, Xing Li, Shuixiang He, Huizhen Fan, Side Liu, Guoxin Zhang, Jianhua Tang, Caibin Huang, Qin Du, Xiaoyan Wang, Baohong Xu, Yiqi Du, Qikui Chen, Bangmao Wang, Ying Chen, Xianghui Duan, Yong Xie, Lijuan Huo, Xiaohua Hou, Nonghua Lu   +23 more
doaj   +1 more source

Functional diseases of the gastrointestinal tract in the context with overlapping functional disorders: current status of the problem [PDF]

Терапевтический архив, 2020
Functional diseases of the gastrointestinal tract cause significant damage to the health care system. Their frequent combination in the same patient with the migration of clinical symptoms throughout the digestive tube is accompanied by continuous ...
M. A. Osadchuk, A. A. Svistunov, N. V. Kireeva, M. M. Osadchuk   +3 more
doaj   +1 more source

Triple Therapy with High-Dose Proton-Pump Inhibitor, Amoxicillin, and Doxycycline Is Useless for Helicobacter pylori Eradication: A Proof-of-Concept Study [PDF]

, 2014
INTRODUCTION: Helicobacter pylori resistance to antibiotics is steadily increasing and multidrug-resistant strains are common and difficult to eliminate, mainly in countries where bismuth, tetracycline, furazolidone, and rifabutin are unavailable. AIM:
Akyildiz, Alestig, Barza, Basu, Bayerdorffer, Boer, Borody, Cammarota, Chuah, Cianci, Clinical and Laboratory Standards Institute, Francesco, Francesco, Gerrits, Gisbert, Gisbert, Gisbert, Glocker, Glupczynski, Graham, Graham, Graham, Heep, Hulst, Inoue, Janssen, Kirchheiner, Koletzko, Kuo, Labenz, Loo, Malaty, Malfertheiner, Malfertheiner, McNicholl, Megraud, Megraud, Miehlke, Mégraud, Oleastro, Perri, Realdi, Rimbara, Sanches, Shirai, Taghavi, Tokoro, Usta, Villoria, Wang   +49 more
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The influence of CYP2C19 polymorphism on the effectiveness of the treatment of acid-dependent diseases

Медицинский совет, 2022
Introduction. In modern systematic reviews, there is a point of view that CYP2C19 polymorphism affects the results of treatment of peptic ulcer, erosive esophagitis and eradication of Helicobacter pylori.Оbjective.
V. V. Tsukanov, A. V. Vasyutin, Ju. L. Tonkikh, M. V. Smolnikova, M. A. Cherepnin, N. A. Maslennikova, N. V. Pavlova   +6 more
doaj   +1 more source

Safety and efficacy of vismodegib in patients aged ≥65 years with advanced basal cell carcinoma. [PDF]

, 2016
Because many patients with unresectable basal cell carcinoma (BCC) are aged ≥65 years, this study explores the efficacy and safety of vismodegib in these patients with locally advanced (la) or metastatic (m) basal cell carcinoma (BCC) in the ERIVANCE BCC
Arron, Sarah, Chang, Anne, Day, Bann-Mo, Lewis, Karl, McKenna, Edward, Migden, Michael, Sekulic, Aleksandar, Solomon, James, Yoo, Simon   +8 more
core   +2 more sources

Features of GERD therapy in obese patients: A review

Consilium Medicum, 2023
Epidemiological, endoscopic and pathophysiological studies confirm the relationship between obesity and gastroesophageal reflux disease (GERD) and is characterized by a more severe course, has clinical and pathophysiological features. In the treatment of
Natalia V. Bakulina, Sergey V. Tikhonov, Anastasia Yu. Efremova, Vakhtang V. Mirtskhulava   +3 more
doaj   +1 more source

Deprescribing and Optimal Selection of Proton Pump Inhibitors (Contributions of the 26th United Russian Gastroenterology Week)

Российский журнал гастроэнтерологии, гепатологии, колопроктологии, 2020
Aim. Presentation of the Forum “Deprescribing and optimal selection of proton pump inhibitors” held in Moscow on 29 September 2020 during the 26th United Russian Gastroenterology Week.Key points.
V. T. Ivashkin, I. V. Maev, A. S. Trukhmanov, A. A. Sheptulin, V. I. Simanenkov, T. L. Lapina, I. B. Khlynov, N. N. Dekhnich, O. D. Lopina, O. P. Alekseeva, N. V. Korochanskaya, M. F. Osipenko, P. V. Pavlov, S. S. Pirogov, G. N. Tarasova, Yu. P. Uspenskiy, D. N. Andreev, D. E. Rumyantseva   +17 more
doaj   +1 more source

CTDSP1 inhibitor rabeprazole regulates DNA-PKcs dependent topoisomerase I degradation and irinotecan drug resistance in colorectal cancer.

PLoS ONE, 2020
Irinotecan specifically targets topoisomerase I (topoI), and is used to treat various solid tumors, but only 13-32% of patients respond to the therapy.
Hiroya Matsuoka, Koji Ando, Emma J Swayze, Elizabeth C Unan, Joseph Mathew, Quingjiang Hu, Yasuo Tsuda, Yuichiro Nakashima, Hiroshi Saeki, Eiji Oki, Ajit K Bharti, Masaki Mori   +11 more
doaj   +1 more source