The effects of rabeprazole on metformin pharmacokinetics and pharmacodynamics in Chinese healthy volunteers [PDF]
Journal of Pharmacological Sciences, 2016 The aim was to investigate the role of rabeprazole on the pharmacokinetics (PK) and pharmacodynamics (PD) of metformin. The in vitro inhibition assays on metformin transport were carried out and showed that the half maximal inhibitory concentration (IC50)
Guojing Liu +8 more
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Rabeprazole suppressed gastric intestinal metaplasia through activation of GPX4-mediated ferroptosis [PDF]
Frontiers in PharmacologyBackgroundGastric intestinal metaplasia is a common pathological feature in patients with Helicobacter pylori (H. pylori) infection. Rabeprazole was widely used as the first-line regimen for H. pylori infectious treatment.
Jing Xie +15 more
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Cells, 2022 There are currently no effective treatments for sepsis and acute respiratory distress syndrome (ARDS). The repositioning of existing drugs is one possible effective strategy for the treatment of sepsis and ARDS.
Colin E. Evans +5 more
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A Decade of Screening and Treating Helicobacter pylori Infection Among First‐Year High School Students in Kyoto, Japan: Annual Trends in Infection, Consultation, and Eradication Success Rates (2015–2023) [PDF]
Helicobacter, Volume 31, Issue 4, July/August 2026.ABSTRACT Background Helicobacter pylori infection is a primary cause of gastric cancer. Although eradication therapy in adulthood suppresses carcinogenesis, its efficacy is limited due to the progression of advanced gastric mucosal atrophy before eradication.
Osamu Handa +3 more
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A Simple and Validated Reverse Phase HPLC Methodfor the Determination of Rabeprazole inPharmaceutical Dosage Forms [PDF]
E-Journal of Chemistry, 2010 A simple and rapid reverse phase high performance liquid chromatography (RP-HPLC) method was developed and validated for quantitative determination of rabeprazole in bulk drug samples and formulations.
Uma Mahesh Karra, Sanjeeva Yarkala
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Synthesis of degradants and impurities of rabeprazole [PDF]
, 2021 Rabeprazole is an antiulcer drug comes under the Pharmacological class (antisecretory compounds) which is Proton-pump inhibitor, and It's used for heartburn, acid reflux and GORD (gastro-oesophageal reflux disease).
Yadav, C. Hazarathaiah +1 more
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Platelets, 2020 Although acid suppressants are needed to attenuate gastrointestinal bleeding (GIB) after percutaneous coronary intervention (PCI), pharmacodynamic interaction between clopidogrel and proton pump inhibitor (PPI) can increase the risk of high platelet ...
Jong-Hwa Ahn +11 more
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Effects of 5 years of treatment with rabeprazole or omeprazole on the gastric mucosa
, 2005 To access publisher full text version of this article. Please click on the hyperlink in Additional Links fieldBACKGROUND: Prolonged gastric acid suppression leads to hypergastrinaemia, which promotes hyperplasia of the enterochromaffin-like (ECL) cells ...
Rindi, Guido +11 more
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Лечащий Врач, 2021 Proton pump inhibitors are a diverse class of drugs with unique acid suppression properties. The aim of the work was to present the therapeutic benefits of rabeprazole and pantoprazole in clinical practice.
E. A. Lyalukova +3 more
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ACTUAL ASPECTS OF ANTI-SECRETOR THERAPY OF GASTROESOPHAGEAL REFLUX DISEASE
Медицинский совет, 2017 In recent years, GERD has attracted increased attention, which is associated with a clear tendency to increase the incidence of the disease. Adequate treatment of GERD is necessary, as this disease worsens the quality of life of patients, and prolonged ...
D. I. Trukhan, I. A. Grishechkina
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