Results 151 to 160 of about 112,284 (228)
ABSTRACT LIN‐24, an aerolysin‐like pore‐forming protein in Caenorhabditis elegans, exemplifies how ancient cytolytic mechanisms have evolved into regulated cellular processes. Initially identified for inducing nonapoptotic, engulfment‐dependent cell death in vulval precursor cells, LIN‐24 has emerged as a multifunctional regulator of metabolism, stress
Sharoen Yu Ming Lim
wiley +1 more source
Diabetic kidney disease, biomarkers, and finerenone
Abstract Diabetic kidney disease (DKD), the leading cause of kidney failure worldwide, is associated with an increased risk of cardiovascular disease (CVD). A complex pathobiology involving hemodynamic, metabolic, and immune dysregulation promotes inflammatory and fibrotic pathways that contribute to kidney disease progression and CVD in individuals ...
Ashish Verma, Ashish Upadhyay
wiley +1 more source
És una aplicació que dona suport a la nova web de RAC 1, gestionant les parts que el CMS web no pot fer o li és complicat. Gestiona els fitxers àudio en format MP3, permet la seva cerca, la gestió de programes i graelles, dona suport a l'app, RSS/Podcast.
openaire +1 more source
Linking Superoxide Production and Scavenging in Plant Development
ABSTRACT Due to their strong oxidizing potential, rapid membrane permeability, and high reactivity, reactive oxygen species (ROS) play essential roles in plant development and stress responses. Superoxide (O2•‐) is a primary product of molecular oxygen reduction and a crucial source of hydrogen peroxide, representing a ROS species of substantial ...
Jan Řehák +3 more
wiley +1 more source
Rac1 meets ubiquitin: New insights in Rac1 signalling
Het cytoskelet bestaat uit eiwitketens (polymeren), waarvan de lengte fluctueren. Het functioneert onder andere als ‘wegennet’ en reguleert het transport van eiwitten naar specifieke plaatsen binnen de cel. Een aantal eiwitten is van belang voor celbeweging, waaronder Rac1.
openaire +1 more source
Objective To investigate whether Rac1 inhibitor has a synergistic effect on temozolomide (TMZ) in inhibiting the proliferation, migration and invasiveness of glioma cells. Methods Human glioma cell lines U87 and U251 were cultured by Rac1 inhibitor,
Xiao-yong HAN +5 more
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