Results 201 to 210 of about 83,967 (245)

Regulation of CFTR stability at the plasma membrane-Mechanisms and therapeutic opportunities in cystic fibrosis. [PDF]

FEBS Lett
Farinha CM, Oliveira J.
europepmc   +1 more source

Acquisition of Resistance to RAS Inhibition Is Associated with the Upregulation of Macropinocytosis through Both PI3K-Dependent and -Independent Signaling. [PDF]

Cancer Res Commun
Robb R, Ackermann SE, Degan SE, Taylor KE, Yang R, Marler AZ, Calvert V, Pierobon M, Lyons S, Barker-Krantz N, Cabrera A, Schaefer A, Herring LE, Cox AD, Petricoin EF, Stalnecker CA, Bryant KL.   +16 more
europepmc   +1 more source

ABL kinases regulate FGF signaling independent of CRK phosphorylation to prevent Peters anomaly type II. [PDF]

Nat Commun
Wu H, Mao Y, Wang Q, Yu H, Bouaziz M, Makrides N, Wang E, Ding Z, Koleske AJ, Radice GL, Hsu J, Zhang X.   +11 more
europepmc   +1 more source

IRF1 Inhibits the Proliferation and Metastasis of Colorectal Cancer by Suppressing the RAS-RAC1 Pathway [Retraction]. [PDF]

Cancer Manag Res
europepmc   +1 more source

Modular Phosphoprotein Signatures Link Rac1 Inhibition to Neurite Morphogenesis in a Dose-Dependent Manner.

Dev Neurosci
Ge Y, Freeborn D, Nash MS, Kodavanti PRS, Shafer TJ, Mack CM, Herr DW.   +6 more
europepmc   +1 more source

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The anti-Rac1-GTP antibody and the detection of active Rac1: a tool with a fundamental flaw

Small GTPases, 2021
Rac1 is a member of the Rho GTPase family and is involved in many cellular processes, particularly the formation of actin-rich membrane protrusions, such as lamellipodia and ruffles. With such a widely studied protein, it is essential that the research community has reliable tools for detecting Rac1 activation both in cellular models and tissues. Using
Martin J, Baker, Marcelo G, Kazanietz
openaire   +2 more sources

Rac1 GTPase: A “Rac” of All Trades [PDF]

Cellular and Molecular Life Sciences, 2008
Rac1, a member of the Rho family of GTPases, is an intracellular transducer known to regulate multiple signaling pathways that control cytoskeleton organization, transcription, and cell proliferation. Deregulated expression or activation patterns of Rac1 can result in aberrant cell signaling and numerous pathological conditions.
J C Mulloy
exaly   +3 more sources