Results 221 to 230 of about 83,967 (245)

Expressions of Rac1, Tiam1 and Cdc42 in retinoblastoma

Experimental Eye Research, 2006
The Rho GTPases are the molecular regulators of the cell motility processes and are involved in cell cycle progression and gene transcription. We studied the expression of Rho-like GTPases molecules, particularly Rac, Tiam1 and cdc42, in retinoblastoma and correlated these with clinicopathological parameters of the tumors.
Mohan, Adithi, Nalini, Venkatesan, Mallikarjuna, Kandalam, Jyotirmay, Biswas, Subramanian, Krishnakumar   +4 more
openaire   +2 more sources

AKAP Functions for Rac1

Science Signaling, 2013
Rac1 binds to the PKA holoenzyme to enable cAMP-mediated enhancement of the activity of the Rac1 effectors of the PAK family of kinases.
openaire   +1 more source

The role of Rac1 and Rac2 in bacterial killing

Cellular Immunology, 2005
The small Rho guanosine triphosphatases (GTPases) Rac1 and Rac2 have distinct roles in regulating neutrophil chemotaxis; however, little is known about their possible unique roles in mediating bacterial killing. To elucidate the relative roles of Rac1 and Rac2 in regulating neutrophil-mediated bacterial killing, we utilized the previously described ...
Adeline Loo Yee, Koh, Chun Xiang, Sun, Fei, Zhu, Michael, Glogauer   +3 more
openaire   +2 more sources

Depressed Without Rac1

Science Signaling, 2013
Treatments that target the GTPase RAC1 signaling could be developed as antidepressants.
openaire   +1 more source

Membrane recruitment of Rac1 triggers phagocytosis

Journal of Cell Science, 2000
ABSTRACT Rac1 is a Rho-family GTP-binding protein that controls lamellipodia formation and membrane ruffling in fibroblasts. Recently, Rac1 and Cdc42, another member of the Rho-family, have been shown to regulate Fc receptor-mediated phagocytosis in macrophages by controlling different steps of membrane and actin dynamics leading to ...
F, Castellano, P, Montcourrier, P, Chavrier   +2 more
openaire   +2 more sources

Rac1 as a therapeutic anticancer target: Promises and limitations

Biochemical Pharmacology, 2022
Gervaise Loirand, Christian Bailly, Vincent Sauzeau   +2 more
exaly  

Characterisation and outcome of RAC1 mutated melanoma

European Journal of Cancer, 2023
Eva Hadaschik, Ralf Gutzmer, Elisabeth Livingstone   +2 more
exaly  

Trapping Rac1

Nature Chemical Biology, 2017
openaire   +1 more source

Rac1 is required for the formation of three germ layers during gastrulation

Oncogene, 1999
Kazuki Nakao, Atsu Aiba, Hiroyuki Sakagami   +2 more
exaly  

The Rac1 Regulator ELMO1 Controls Vascular Morphogenesis in Zebrafish

Circulation Research, 2010
Wolfgang Driever, Jens Kroll, Daniel Epting   +2 more
exaly