Results 101 to 110 of about 15,352 (140)

Inhibitors of De Novo Guanylate Biosynthesis Enhance the Potency of MAPK Cascade Inhibitors Against Colorectal Cancer. [PDF]

Int J Mol Sci
Maslov AA, Trageser NH, Kichina JV, Elamir H, Gardner E, Teaman F, Vishwanath V, Dugas SM, Bianchi-Smiraglia A, Leonova KI, Gurova KV, Nikiforov MA, Kandel ES.   +12 more
europepmc   +1 more source

Guanine Nucleotide Exchange Factors and Small GTPases: Their Regulation and Functions, Diseases, and Therapeutic Targets. [PDF]

MedComm (2020)
Lin Z, Ni C, Jiang H, Yang H, Deng L, Liu P, Li X, Yu Y, Li W, Wang R, Liao B, Kang J, Liu J, Wu X, Ren J, Zhao Y.   +15 more
europepmc   +1 more source

Layilin inhibits integrin activation, and its loss results in platelet hyperactivation via Rac1 in inflammatory bowel disease. [PDF]

Blood
Mellema RA, Queisser KA, Ajanel A, Albtoush N, Smith-Sanchez L, Rondina MT, Will J, Valentine JF, Petrey AC.   +8 more
europepmc   +1 more source

A Pleiotropic and Functionally Divergent <i>RAC3</i> Variant Disrupts Neurodevelopment and Impacts Organogenesis. [PDF]

Cells
Sugawara R, Scala M, Cabet S, Abel C, Januel L, Lesca G, Guibaud L, Le Breton F, Ueda H, Tabata H, Ito H, Nagata KI.   +11 more
europepmc   +1 more source

Fluorescence Lifetime Imaging Application to Probe GTPase Activation in Macrophage Cell Line, Using the Time-Domain FastFLIM Modality. [PDF]

Methods Mol Biol
Miskolci V, de Assis Lima M, Cox D, Hodgson L.   +3 more
europepmc   +1 more source

CLIC5A binds to and stabilizes the open and active conformation of ezrin. [PDF]

J Biol Chem
Rahman MM, Kim JS, Li L, Feisal MR, Mak KYL, Tavasoli M, Wang Z, Ballermann BJ, Hwang PM.   +8 more
europepmc   +1 more source

Research progress of ECT2 and RhoA-related signaling pathways in gynecological tumors. [PDF]

Front Cell Dev Biol
Sheng L, Liang M, Wang Y, Zhou Z, Xie Y, Ke Y, Wu Z.   +6 more
europepmc   +1 more source

New insights into the classification of the RAC1 P29S hotspot mutation in melanoma as an oncogene. [PDF]

Cancer Gene Ther
Mirzaiebadizi A, Ahmadian MR.
europepmc   +1 more source

The small GTPase Rap1A expedites the NOX2 oxidative burst by facilitating Rac and NOX2 autoactivations. [PDF]

FEBS J
Johnson HE, Umutesi HG, Heo J.
europepmc   +1 more source

RAC1 signaling in prostate cancer: VAV GEFs take center stage. [PDF]

Front Cell Dev Biol
Cooke M, Peinetti N, Kazanietz MG, Burnstein KL.   +3 more
europepmc   +1 more source