Results 121 to 130 of about 15,352 (140)

Emerging role of long non‑coding RNAs in the Rho/ROCK signaling pathway in tumor metastasis (Review). [PDF]

Int J Mol Med
Nie H, Yang X, Chen Q, He X, Han Y, He Q, Ou C.   +6 more
europepmc   +1 more source

S-acylation and membrane localization of the small GTPase ARL15 are mediated by the Golgi S-acyltransferases ZDHHC7 and ZDHHC3. [PDF]

J Biol Chem
Chino T, Araki M, Ashi Y, Izawa Y, Nunami Y, Ichikawa Y, Kuroiwa I, Kontani K.   +7 more
europepmc   +1 more source

M-Ras distinct activation scenarios: A mechanistic outlook and targeting. [PDF]

Comput Struct Biotechnol J
Xu L, Liu Y, Jang H, Nussinov R.
europepmc   +1 more source

The Role of the TG2-GPR56 Complex in Cutaneous Squamous Cell Carcinoma (CSCC) Aggression and Therapeutic Resistance. [PDF]

Int J Mol Sci
Weber DJ, Cook ME, Yu W, Redondo M, Godoy-Ruiz R.   +4 more
europepmc   +1 more source

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Regulation of the human neutrophil NADPH oxidase by the Rac GTP-binding proteins

Current Opinion in Cell Biology, 1994
Recent progress in our understanding of the regulation of the phagocyte NADPH oxidase by the Rac GTP-binding protein(s) has provided the first detailed glimpse into the mechanisms of leukocyte regulation by a small GTP-binding protein. Studies over the past year have indicated that the activity of the NADPH oxidase can be modulated by regulation of the
Gary M Bokoch, G M Bokoch
exaly   +3 more sources

Activation of the small GTP-binding proteins rho and rac by growth factor receptors

Journal of Cell Science, 1995
ABSTRACT The small GTP-binding proteins, rho and rac, control signal transduction pathways that link growth factor receptors to the activation of actin polymerization. In Swiss 3T3 cells, rho proteins mediate the lysophosphatidic acid and bombesin-induced formation of focal adhesions and actin stress fibres, whilst rac proteins are ...
Phillip T Hawkins, Len R Stephens, Catherine D Nobes   +2 more
exaly   +3 more sources

A dominant inhibitory version of the small GTP-binding protein Rac disrupts cytoskeletal structures and inhibits developmental cell shape changes in Drosophila

Development, 1995
ABSTRACT The Rho subfamily of Ras-related small GTP-binding proteins is involved in regulation of the cytoskeleton. The cytoskeletal changes induced by two members of this subfamily, Rho and Rac, in response to growth factor stim-ulation, have dramatic effects on cell morphology.
Harden, N., Loh, H.Y., Chia, W., Lim, L.
openaire   +2 more sources

Transgenic tobacco plants that express an antisense construct derived from a Medicago sativa cDNA encoding a Rac-related small GTP-binding protein fail to develop necrotic lesions upon elicitor infiltration

Molecular and General Genetics MGG, 2000
Using an RT-PCR approach a rac-related cDNA clone, designated Ms-rac1, was isolated from Medicago sativa (alfalfa). Ms-rac1 encodes a putative protein of 197 amino acids, which is closely related to known Rac-related GTP-binding proteins from Pisum sativum and Arabidopsis thaliana.
Schiene, K, Pühler, Alfred, Niehaus, Karsten   +2 more
openaire   +3 more sources

P-73: Identification of Napl (Nck-associated protein 1) as a target of activated GTP-binding protein Rac

Experimental and Clinical Endocrinology & Diabetes, 2009
Yukari Kitamura, Wataru Ogawa, Tadahiro Kitamura, Masato Kasuga   +3 more
openaire   +1 more source