Results 11 to 20 of about 1,478 (205)

Racecadotril versus loperamide for the treatment of acute diarrhoea

The Egyptian Journal of Internal Medicine, 2023
© The Author(s) 2023. Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate ...
Poulami Roy, Novonil Deb
doaj   +3 more sources

Enhancement of dissolution rate of racecadotril by liquisolid compact technology

Brazilian Journal of Pharmaceutical Sciences, 2023
The current investigation was used to improve the rate of dissolution of an anti-diarrheal drug i.e., racecadotril (RT) at low pH conditions (i.e., in the stomach) by reducing the water secretion and electrolyte in to the intestine by liquisolid tablets.
Bhaskar Daravath, Shalini Somalanka
doaj   +2 more sources

Racecadotril for acute diarrhoea in children. [PDF]

Cochrane Database Syst Rev, 2019
Acute diarrhoea is a leading cause of death for children under five years of age. Most deaths are caused by excessive fluid and electrolyte losses. Racecadotril is an anti-secretory drug that has been used for acute diarrhoea in children as an adjunct to oral rehydration therapy.To assess the efficacy and safety of racecadotril for treating acute ...
Liang Y, Zhang L, Zeng L, Gordon M, Wen J.   +4 more
europepmc   +4 more sources

Racecadotril in the treatment of acute diarrhea in children: a systematic, comprehensive review and meta-analysis of randomized controlled trials [PDF]

BMC Pediatrics, 2018
Background Racecadotril is a guideline-recommended option for the treatment of acute diarrhea in children but existing guidelines and previous reviews of the field are based on a small fraction of published evidence.
Marion Eberlin, Min Chen, Tobias Mueck, Jan Däbritz   +3 more
doaj   +2 more sources

Evaluating the Efficacy of Racecadotril in Combination with Oral Rehydration in Children with Acute Diarrhoea: A Randomised Controlled Trial [PDF]

Journal of Clinical and Diagnostic Research
Introduction: Acute watery diarrhoea in early childhood frequently necessitates hospital admission. Although Oral Rehydration Salts (ORS) with zinc effectively prevent and treat dehydration, they do not consistently shorten illness duration or reduce ...
Uddhava V Kinhal, V Vidhyadhar, N Supriya   +2 more
doaj   +2 more sources

CRISPR/Cas9-engineering of Kell null erythrocytes to unveil host targeted irresistible antimalarial [PDF]

Communications Biology
Malaria elimination faces challenges from drug resistance, stemming from mutations within the parasite’s genetic makeup. Genetic adaptations in key erythrocyte proteins offer malaria protection in endemic regions.
Geeta Kumari, Pragya Gupta, Sangam G. Goswami, Ravi Jain, Sakshi Anand, Shreeja Biswas, Swati Garg, Priya Thakur, Vinodh Saravanakumar, V. R. Arvinden, Bidhan Goswami, Ipsita Pal Bhowmick, Narla Mohandas, Jeremy Burrows, Sivaprakash Ramalingam, Shailja Singh   +15 more
doaj   +2 more sources

Neprilysin inhibition for pulmonary arterial hypertension: a randomized, double-blind, placebo-controlled, proof-of-concept trial. [PDF]

Br J Pharmacol, 2019
This is the peer reviewed version of the following article: Hobbs AJ, Moyes AJ, Baliga RS, et al. Neprilysin inhibition for pulmonary arterial hypertension: a randomized, double‐blind, placebo‐controlled, proof‐of‐concept trial. Br J Pharmacol.
Hobbs AJ, Moyes AJ, Baliga RS, Ghedia D, Ochiel R, Sylvestre Y, Doré CJ, Chowdhury K, Maclagan K, Quartly HL, Sofat R, Smit A, Schreiber BE, Coghlan GJ, MacAllister RJ.   +14 more
europepmc   +3 more sources

Racecadotril no Tratamento da Diarreia Aguda em Idade Pediátrica: Qual a Evidência?

Gazeta Médica
A gastroenterite aguda (GEA) continua a ser uma das patologias mais frequentes em idade pediátrica, sendo que a rehidratação oral permanece a pedra angular do seu tratamento.
Sara Pereira Santos, Rita Pedrosa, Isabel Pinho Teixeira, Ana Filipa Amorim, Isabel Pinto Pais, Cristina Costa, Andreia Ribeiro   +6 more
doaj   +6 more sources

Prediction and identification of synergistic compound combinations against pancreatic cancer cells. [PDF]

iScience, 2021
Resistance to current therapies is common for pancreatic cancer and hence novel treatment options are urgently needed. In this work, we developed and validated a computational method to select synergistic compound combinations based on transcriptomic ...
KalantarMotamedi Y, Choi RJ, Koh SB, Bramhall JL, Fan TP, Bender A.   +5 more
europepmc   +6 more sources

Greenness assessment profile of experimentally designed chromatographic method for the simultaneous analysis of ofloxacin and racecadotril in the presence of racecadotril impurities

Talanta Open
Experimental design beats the conventional one variable at a time (OVAT) to improve the chromatographic separations with lowest consumption of resources and maximum acceptable results for the separated peaks.
Nada Nabil, Ghada A. Sedik, Hala E. Zaazaa, Sally S. El-Mosallamy   +3 more
doaj   +2 more sources