Racecadotril Versus Loperamide for Acute Diarrhea of Infectious Origin in Adults: A Systematic Review and Meta‐Analysis [PDF]
Health Science ReportsBackground and Aims Loperamide and racecadotril are two antidiarrheal medications with different mechanisms of action that are highly important for the treatment of diarrhea as a result of infectious pathology.
Maryam Aziz +12 more
doaj +3 more sources
A comprehensive review of the pharmacodynamics, pharmacokinetics and clinical effects of the neutral endopeptidase inhibitor racecadotril [PDF]
Frontiers in Pharmacology, 2012 Racecadotril, via its active metabolite thiorphan, is an inhibitor of the enzyme neutral endopeptidase (NEP, EC 3.4.24.11), thereby increasing exposure to NEP including enkephalins and atrial natriuretic peptide.
Marion eEberlin +2 more
doaj +10 more sources
National Consensus for the Management of Acute Gastroenteritis in Jordanian Children: Consensus Recommendations Endorsed by the Jordanian Paediatric Society [PDF]
International Journal of Pediatrics, 2022 Diarrhoeal diseases are one of the leading worldwide preventable causes of death among children under 5 years of age. Almost half of children do not receive optimal acute gastroenteritis (AGE) treatment in Jordan.
Mohammed Rawashdeh +6 more
doaj +3 more sources
Research in Pharmaceutical Sciences, 2021 Background and purpose: Although pain is one of the most common symptoms of diseases, it is often mismanaged due to limited access to painkillers and ineffectiveness, unacceptable side effects, or the possibility of abuse.
Mehdi Asadi +5 more
doaj +2 more sources
Evaluation of the Effect of Ethyl Acrylate-Methyl Methacrylate Copolymer in Racecadotril Dispersible Tablet. [PDF]
Turk J Pharm Sci, 2022 Pınarbaşlı O +5 more
europepmc +2 more sources
CRISPR/Cas9-engineering of Kell null erythrocytes to unveil host targeted irresistible antimalarial [PDF]
Communications BiologyMalaria elimination faces challenges from drug resistance, stemming from mutations within the parasite’s genetic makeup. Genetic adaptations in key erythrocyte proteins offer malaria protection in endemic regions.
Geeta Kumari +15 more
doaj +2 more sources
Role of Racecadotril in Children with Acute Diarrhea
Dhaka Shishu (Children) Hospital Journal, 2021 Background: Diarrhea is a leading cause of illness and death among children in developing countries. Racecadotril (acetorphan), an enkephalinase inhibitor with antisecretory and anti-diarrheal actions, is an effective and safe treatment for acute diarrhea in adults and children. Objectives: The objective of this study is to evaluate the efficacy ...
Sheikh Farjana Sonia +6 more
openaire +3 more sources
Talanta OpenExperimental design beats the conventional one variable at a time (OVAT) to improve the chromatographic separations with lowest consumption of resources and maximum acceptable results for the separated peaks.
Nada Nabil +3 more
doaj +2 more sources
Efficacy of Racecadotril in a Patient Affected by a Therapy-Refractory VIPoma and Carcinoid Syndrome. [PDF]
JCEM Case RepBoesenkoetter J +4 more
europepmc +2 more sources
Adherence to treatment guidelines for acute diarrhoea in children up to 12 years in Ujjain, India - a cross-sectional prescription analysis [PDF]
BMC Infectious Diseases, 2011 Background Diarrhoea accounts for 20% of all paediatric deaths in India. Despite WHO recommendations and IAP (Indian Academy of Paediatrics) and Government of India treatment guidelines, few children suffering from acute diarrhoea in India receive low ...
Marrone Gaetano +4 more
doaj +4 more sources