Results 171 to 180 of about 89,874 (280)

Advances in the Different Synthetic Routes of Fluorinated Hydrazines

The Chemical Record, EarlyView.
This review highlights the various routes to the preparation of fluorinated hydrazines, thereby promoting the exploration of innovative methods for the synthesis of new N‐fluorinated hydrazines. Their synthesis mainly involves synthetic routes such as organometallic, organocatalytic, and photocatalytic.
Dimitra Kyrko, Benoît Crousse
wiley   +1 more source

On the Mechanism of Random Handedness Generation in the Reactions of Heterocyclic Aldehydes with Diallylboronates. [PDF]

Molecules
Mikhailov O, Gridnev ID.
europepmc   +1 more source

Psychedelics, entactogens and psychoplastogens for depression and related disorders

British Journal of Pharmacology, EarlyView.
Currently, the most actively investigated rapidly acting antidepressants, anxiolytics and/or anti PTSD agents, include psychedelics e.g. psilocybin, LSD, N,N‐dimethyltryptamine, ayahuasca; non‐hallucinogenic entactogens, e.g. MDMA; psychoplastogens which rapidly promote neuroplasticity, e.g.
Daniel Hoyer
wiley   +1 more source

The Rippled Beta-Sheet: An Old Prediction Inspires a New Field. [PDF]

Chembiochem
Raskatov JA.
europepmc   +1 more source

Differential effects of ketamine enantiomers on EEG parameters including the gamma‐delta shift phenomenon

British Journal of Pharmacology, EarlyView.
Background and Purpose Ketamine consists of two enantiomers, (R)‐ketamine and (S)‐ketamine, which exhibit distinct pharmacological properties. Currently, only the (S)‐enantiomer has been approved for the treatment of major depressive disorder, whereas recent clinical studies have failed to demonstrate an antidepressant effect for (R)‐ketamine.
Szabolcs Koncz, Dóra Pothorszki, Noémi Papp, Donát Pál, György Bagdy   +4 more
wiley   +1 more source

Sex, drugs, and arousal-two randomized trials on the effects of ketamine on sexual arousal and calcarine gyrus activity. [PDF]

Ther Adv Psychopharmacol
Klöbl M, Liebe T, Dörl G, Stöhrmann P, Schmidt C, Briem E, Milz C, Schlosser G, Kathofer M, Gomola D, Godbersen GM, Crone JS, Lanzenberger R, Spies M.   +13 more
europepmc   +1 more source

1166. Helianthus occidentalis Riddell

Curtis's Botanical Magazine, EarlyView.
Summary Helianthus occidentalis Riddell (Compositae: Heliantheae: Helianthinae) is described and illustrated. The species' placement in the genus is commented on, as are the differences in infrageneric placement of the other species Heiser originally grouped H. occidentalis with.
Nicholas Hind, Christabel King
wiley   +1 more source

Catalytic Deracemization of 1,2-Aminoalcohols through Enantioselective Hydrogen Atom Abstraction. [PDF]

J Am Chem Soc
Davies DJ, Lahdenperä ASK, Phipps RJ.
europepmc   +1 more source

Human IDO2 exhibits unique binding affinities distinct to those of human IDO1

The FEBS Journal, EarlyView.
Although indoleamine 2,3‐dioxygenase 2 (IDO2) is highly homologous to IDO1, it displays markedly lower catalytic activity. We found that IDO2 binds L‐tryptophan (L‐Trp) in a flipped orientation stabilized by the IDO2‐specific residue His143. Replacement of His143 with the IDO1‐equivalent tyrosine restored an IDO1‐like binding mode and increased ...
Shunsuke Nogi, Ayumu Takahashi, So Murakami, Nami Adachi, Tina Fujimoto, Yohta Fukuda, Taku Yamashita, Tsuyoshi Inoue, Hirofumi Tsujino   +8 more
wiley   +1 more source

Intermolecular Stacking-Instructed Chiral Preference in Covalent 2 + 2 Macrocyclization. [PDF]

JACS Au
Huang ZS, Wang WR, Yang FH, Gou F, Jiang L, Qiu CC, Tai YY, Yan XS, Wu X, Jiang T, Jiang YB.   +10 more
europepmc   +1 more source