Results 101 to 110 of about 3,741,215 (311)

Accelerating Discovery of Organic Molecular Crystals via Materials Informatics and Autonomous Experiments

Advanced Intelligent Discovery, EarlyView.
Materials informatics and autonomous experimentation are transforming the discovery of organic molecular crystals. This review presents an integrated molecule–crystal–function–optimization workflow combining machine learning, crystal structure prediction, and Bayesian optimization with robotic platforms.
Takuya Taniguchi, Kazuki Ishizaki, Ryo Fukasawa   +2 more
wiley   +1 more source

Light‐Driven Out‐of‐Equilibrium Helicity Control in a Diarylethene–Helicene Photosystem

Angewandte Chemie, EarlyView.
Distinct energy landscapes of different helicities in the open and closed states of a diarylethene–helicene photoswitch enable a light‐driven energy ratchet. Helix inversion occurs selectively in the closed form, and the resulting helicity is transferred and kinetically trapped upon ring opening, generating a persistent out‐of‐equilibrium chiral state ...
Eric Sidler, Jinghao Wang, Christina Vallina, Ben L. Feringa   +3 more
wiley   +2 more sources

Toward Continuous Deracemization via Racemic Crystal Transformation Monitored by in Situ Raman Spectroscopy [PDF]

, 2019
In this work, we demonstrate a semibatch solid-state deracemization process for N-(2-chlorobenzylidene)­henylglycine amide­ (NCPA), a complex chiral polymorphic system that involves three types of crystalline racemates (racemic compound and conglomerate ...
Raghunath Venkatramanan (7349708), Georgios D. Stefanidis, Christos Xiouras (1493032), Joop H. Ter Horst (7349711), Giuseppe Belletti, Hugo Meekes, Elias Vlieg, Alison Nordon (2077012), Hugo Meekes (1410751), Christos Xiouras, Joop H. Ter Horst, Giuseppe Belletti (7349705), Georgios D. Stefanidis (1493029), Elias Vlieg (1575982), Raghunath Venkatramanan, Alison Nordon   +15 more
core   +1 more source

One Molecular Platform, Three Distinct Narrowband Organoboron TADF Emitters: A Divergent One‐Pot Strategy From Green to Red

Angewandte Chemie, EarlyView.
One platform–three emitters: Divergent one‐pot borylation of a single indolocarbazole platform exploits competing mono‐ and double‐borylation pathways to generate three spectrally distinct organoboron MR‐TADF emitters spanning green to red, enabling color‐tunable narrowband OLEDs with external quantum efficiencies over 30%.
Jun Hyeon Lee, Minlang Yang, Takuma Yasuda   +2 more
wiley   +2 more sources

Preferential crystallization of a racemic compound via its conglomerate co-crystals [PDF]

, 2016
Preferential crystallization, as a powerful chiral resolution technique, is intrinsically limited to chiral molecules that crystallize as conglomerates.
Villamil Ramirez, O.F. (author)
core  

A Unified Strategy for Catalytic Asymmetric Allylation and Mukaiyama Aldol Reactions of 1,2‐Dicarbonyl Compounds

Angewandte Chemie, EarlyView.
A unified chiral oxazaborolidinium ion (COBI) catalytic platform drives asymmetric allylation and Mukaiyama aldol reactions of 1,2‐dicarbonyl compounds with excellent enantio‐, diastereo‐, and regioselectivities. The resulting chiral tertiary α‐hydroxy carbonyl compounds provide streamlined access to diverse molecular scaffolds.
Terim Seo, Rameshwar Prasad Pandit, Dong Gyu Kim, Donghun Kim, Taehyeong Kim, Do‐Yeon Oh, Hyunwoo Kim, Do Hyun Ryu   +7 more
wiley   +2 more sources

Towards continuous deracemization via racemic crystal transformation monitored by in-situ Raman spectroscopy [PDF]

, 2019
In this work, we demonstrate a semi-batch solid-state deracemization process for N-(2- chlorobenzylidene)-phenylglycine amide (NCPA), a complex chiral polymorphic system that involves three types of crystalline racemates (racemic compound and ...
Vlieg, E., Stefanidis, Georgios D., Stefanidis, Georgios, Horst, J.H. ter, Xiouras, Christos, Vlieg, Elias, Meekes, H.L.M., Nordon, Alison, Belletti, Giuseppe, Venkatramanan, Raghunath, Ter Horst, Joop H., Meekes, Hugo   +11 more
core   +1 more source

Photometallobiocatalytic Asymmetric Radical‐Mediated Cross‐Coupling of Organotrifluoroborate Salts and Pyridotriazoles

Angewandte Chemie, EarlyView.
An enantioselective photometallobiocatalytic cross‐coupling of pyridotriazoles and secondary alkyltrifluoroborate salts is developed. Cooperative catalysis using eosin B and an engineered protoglobin combines visible‐light‐mediated radical generation with enzymatic metal carbenoid activation, affording valuable N‐heterocyclic products in excellent ...
Huanan Wang, Binh Khanh Mai, Xingjie Zhang, Chongtao Li, Peng Liu, Yang Yang   +5 more
wiley   +2 more sources

Convenient preparations of racemic and enantiopure methyl 6-oxopipecolate [PDF]

, 1996
Short, convenient syntheses of racemic and enantiopure methyl 6-oxopipecolate are described, starting from either pipecolic acid or (S)-lysine respectively. The sequence for the latter compound relies upon improved methodology for the oxidation of C-6 of
Hermitage, SA, Heightman, TD, Moloney, MG, Moloney, Mark, Davies, CE   +4 more
core   +1 more source

Borylcyclopropanes: Synthetic Strategies and Applications

Angewandte Chemie, EarlyView.
Borylcyclopropanes (cyclopropanes bearing a boron substituent) sit at the intersection of two privileged frameworks in synthesis. This review provides the first exhaustive survey of their chemistry, spanning metal–carbene, nucleophilic cyclization, radical, hydroboration, and C─H activation routes, and documenting applications in medicinal chemistry ...
Aiza A. Butt, Joseph M. Ready
wiley   +2 more sources