Results 111 to 120 of about 23,430 (289)

Crystal structure of 2-chloro-1-(3-ethyl-2,6-diphenylpiperidin-1-yl)ethanone

Acta Crystallographica Section E: Crystallographic Communications, 2015
In the racemic title compound, C21H24ClNO, the dihedral angle between the planes of the benzene rings is 86.52 (14)° and those between the benzene rings and the piperidine ring are 61.66 (14) and 86.39 (14)°.
V. Shreevidhyaa Suressh, B. K. Revathi, S. Abdul Basheer, S. Ponnuswamy, G. Usha   +4 more
doaj   +1 more source

Crystallization of the Racemic Conglomerate and Racemic Compound of Efonidipine [PDF]

Proceedings of the 2016 International Conference on Biological Engineering and Pharmacy (BEP 2016), 2017
Wen LI, Yuzhen YU, Zhanjun LI, Linyuan ZHU   +3 more
openaire   +1 more source

(1aR*,2R*,7S*,7aS*)-rel-3,6-Dimethoxy-2-methyl-1a,2,7,7a-tetrahydro-2,7-epoxy-1H-cyclopropa[b]naphthalene

IUCrData, 2016
In the racemic title compound, C14H16O3, the dihedral angle formed by the mean planes of the cyclopropane and benzene rings is 5.0 (2)°. In the crystal, a pair of weak C—H...O hydrogen bonds connect two molecules related by a twofold rotation axis, thus ...
Alan J. Lough, Emily Carlson, William Tam   +2 more
doaj   +1 more source

Unraveling hidden symmetry breaking in racemic compounds

Proceedings of the National Academy of Sciences
Racemic compounds, consisting of an equimolar mixture of enantiomers in crystalline form, are conventionally regarded as fully symmetric and are often dismissed as a trivial phenomenon due to their abundance—as they account for a substantial fraction (90 to 95%) of entries in structural databases.
Weihao Wang, Fangyi Chen, Zhenghong Chen, Yutong Sun, Feng Liu, Shaodong Zhang   +5 more
openaire   +3 more sources

Application of crystallization inhibitors to chiral separations. 1. Design of additives to discriminate between the racemic compound and the pure enantiomer of mandelic acid

, 2007
In the context of the potential use of crystallization for spontaneous separation of racemates, it is well-known that the frequent appearance of racemic solid forms (racemic compounds) is a serious obstacle.
Davey, R. J.; id_orcid, Blagden, N., Mughal, R. K.   +2 more
core   +1 more source

(Acetato-κ2O,O′)[2′-(di-tert-butylphosphanyl)-1,1′-biphenyl-κ2P,C2]palladium(II)

Acta Crystallographica Section E, 2012
The structure of the title compound, [Pd(C2H3O2)(C20H26P)], shows a distorted square-planar geometry for the PdII atom, with significant deviations being evident owing to the asymmetric coordination mode of the acetate ligand. A weak intramolecular C&
Charmaine Arderne, Cedric W. Holzapfel
doaj   +1 more source

A Chiral Saddle‐Shaped Nanographene With Two Heptagon‐Embedded [4]Helicenes

Angewandte Chemie International Edition, EarlyView.
We present a novel synthetic strategy toward a chiral saddle‐shaped nanographene (cSNG) via a two‐step oxidation of a prochiral anthracene precursor. The Scholl‐type oxidation first yields a key intermediate with sp3‐defect heptagons, and subsequent oxidative dehydrogenation affords fully conjugated cSNG.
Felix Trautner, Boris Borrisov, Philipp Royla, Hongqing Zhao, Hartmut Komber, Li Wan, Evgenia Dmitrieva, Ji Ma, Jan J. Weigand, Qun Yang, Xinliang Feng, Wenhui Niu   +11 more
wiley   +1 more source

Synthesis and Biological Evaluation of Benzochromenopyrimidinones as Cholinesterase Inhibitors and Potent Antioxidant, Non-Hepatotoxic Agents for Alzheimer’s Disease

Molecules, 2016
We report herein the straightforward two-step synthesis and biological assessment of novel racemic benzochromenopyrimidinones as non-hepatotoxic, acetylcholinesterase inhibitors with antioxidative properties.
Youssef Dgachi, Oscar M. Bautista-Aguilera, Mohamed Benchekroun, Hélène Martin, Alexandre Bonet, Damijan Knez, Justyna Godyń, Barbara Malawska, Stanislav Gobec, Mourad Chioua, Jana Janockova, Ondrej Soukup, Fakher Chabchoub, José Marco-Contelles, Lhassane Ismaili   +14 more
doaj   +1 more source

Toward Continuous Deracemization via Racemic Crystal Transformation Monitored by in Situ Raman Spectroscopy

, 2019
In this work, we demonstrate a semibatch solid-state deracemization process for N-(2-chlorobenzylidene)­henylglycine amide­ (NCPA), a complex chiral polymorphic system that involves three types of crystalline racemates (racemic compound and conglomerate ...
Raghunath Venkatramanan (7349708), Georgios D. Stefanidis, Christos Xiouras (1493032), Joop H. Ter Horst (7349711), Giuseppe Belletti, Hugo Meekes, Elias Vlieg, Alison Nordon (2077012), Hugo Meekes (1410751), Christos Xiouras, Joop H. Ter Horst, Giuseppe Belletti (7349705), Georgios D. Stefanidis (1493029), Elias Vlieg (1575982), Raghunath Venkatramanan, Alison Nordon   +15 more
core   +1 more source

Preferential crystallization of a racemic compound via its conglomerate co-crystals

, 2016
Preferential crystallization, as a powerful chiral resolution technique, is intrinsically limited to chiral molecules that crystallize as conglomerates.
Villamil Ramirez, O.F. (author)
core