Results 221 to 230 of about 23,430 (289)

Safety and tolerance of oral ketamine: A systematic review

Psychiatry and Clinical Neurosciences, EarlyView.
Oral ketamine has gained increasing interest beyond anesthesia, particularly for treatment‐resistant depression, chronic pain, and pediatric procedural sedation. Despite expanding off‐label use, there is no standardized pharmaceutical formulation, and long‐term safety remains uncertain.
Nathalia Novaretti, Rebeca Mendes P. Pessoa, Jaime Eduardo Cecílio Hallak, Rafael Guimarães dos Santos, Marcos Hortes N. Chagas   +4 more
wiley   +1 more source

Unlocking Selenium Chemical Space via a Programmable Synthesis Platform Bearing Cannabinoid Receptor Recognition Motifs. [PDF]

J Am Chem Soc
Iyer MR, Bhattacharjee P, Dutta S, Lobe MMM, Volesky PD, Godlewski G, Puhl HL, Hassan SA.   +7 more
europepmc   +1 more source

Rapid disruption of pollination function by the invasive plant Impatiens glandulifera

Plant Biology, EarlyView.
Invasion by Impatiens glandulifera rapidly disrupts pollination of the native plant Stachys sylvatica by altering pollen transport by shared bumblebee pollinators. A short‐term field introduction revealed a dramatic decline in conspecific pollen deposition within 4 days, showing that pollination function can collapse quickly following invasion, even ...
R. Pérez‐Barrales, L. M. Taylor, G. Horn, S. Ben‐Menni Schuler   +3 more
wiley   +1 more source

Photochemical Deracemization of Chromanes and its Application to the Synthesis of Enantiopure Bioactive Compounds. [PDF]

Angew Chem Int Ed Engl
Ghosh B, Iglhaut M, Babushkina D, Pauls M, Bannwarth C, Bach T.   +5 more
europepmc   +1 more source

Serine Octamer Substitution Reactions With α‐Hydroxy Acids

Rapid Communications in Mass Spectrometry, Volume 40, Issue 18, 30 September 2026.
ABSTRACT Rationale The amino acid serine forms chiral magic number clusters, which can be studied using mass spectrometry (MS). Serine octamer clusters are also known to incorporate one or two nonserine monomers with serine monomers to make up the octamer.
Keerthana Unni, Brison A. Shira, Dylan T. Holden, Thalappil Pradeep, R. Graham Cooks   +4 more
wiley   +1 more source

A Novel Class of Orally Bioavailable Phenylglycine-Benzoxaborole Conjugates with Antimalarial Activity and Potentially Novel Mechanism of Action. [PDF]

ACS Med Chem Lett
Morake M, Taylor D, Coertzen D, Njoroge M, Krugmann L, Leshabane M, da Rocha S, Qahash T, Girling G, Coyle R, Lee MCS, Wittlin S, Llinás M, Birkholtz LM, Basarab GS, Chibale K.   +15 more
europepmc   +1 more source

Design, Synthesis, and Biological Evaluation of Chiral Urea and Thiourea Derivatives as Multitarget‐Directed Anti‐Alzheimer Agents

Drug Development Research, Volume 87, Issue 5, August 2026.
ABSTRACT A series of novel chiral urea and thiourea compounds were designed as multitarget‐directed ligands for Alzheimer's disease and evaluated against hAChE, hBChE, and hMAO‐B, with exploratory assessment of HSD10. These chiral compounds were synthesized and fully characterized, and their enantiopurity was confirmed via HPLC.
Sule Erol Gunal, Senel Teke Tuncel, İlke Demir, İpek Baysal, Gökçen Telli, Safiye Sag Erdem, Gulberk Ucar, Michaela Hanzlova, Kamil Musilek, İlknur Dogan, Nesrin Gokhan Kelekci   +10 more
wiley   +1 more source

A facile and practical method for the synthesis of <i>trans</i>-(±)-taxifolin and its derivatives via Darzens reaction. [PDF]

Beilstein J Org Chem
Peng B, Yang P, Khan M, Lin X, Wu J, Fu P, Wu Q.   +6 more
europepmc   +1 more source

Thermal studies of optically active compounds and their corresponding racemic compounds

, 1988
openaire   +1 more source

Photochemistry of N‐Substituted, N′‐Tosyl Diphenyl Sulfondiimines

Journal of Physical Organic Chemistry, Volume 39, Issue 8, August 2026.
The irradiation of N‐substituted, N′‐tosyl diphenyl sulfondiimines with UV light induces the sequential photorelease of two different nitrenes. ABSTRACT Sulfondiimines are an emerging sulfur(VI) functional group with increasing use in synthesis and medicinal chemistry, yet their photochemical behavior has remained largely unexplored.
Bashar Aziz, Paul Danyi, John P. Carney, Ryan D. McCulla   +3 more
wiley   +1 more source