Results 151 to 160 of about 49,012 (231)

Aging‐Derived Alterations in Genomic, Immune, and Metabolic Networks: Implications for Cancer Development and Therapy

MedComm – Oncology, Volume 5, Issue 1, March 2026.
Ageing acts as a double‐edged sword in cancer. In the elderly, open chromatin, immunosenescence, and chronic inflammation drive SASP (IL‐6, MMPs), MDSC accumulation and T‐cell suppression, fostering tumor‐promoting microenvironments and limited therapeutic benefit.
Qi Wang, Xue Sun, Xinhao Han, Xingda Zhang, Wenzheng Wang, Hongbin Wang, He Ren, Lina Gu   +7 more
wiley   +1 more source

Cellular Stress, Inflammation and Barrier Damage in Gut Epithelial Cells Caused by Aspartame

Allergy, Volume 81, Issue 3, Page 884-901, March 2026.
This study shows that aspartame, at dietary‐relevant doses, induces cytotoxicity, cellular distress associated with endoplasmic reticulum stress, oxidative stress, DNA replication and repair mechanism disturbance culminating in epithelial barrier damage.
Yagiz Pat, Duygu Yazici, Can Zeyneloglu, Huseyn Babayev, Sena Ardicli, Asuncion Garci‐Sanchez, Xiangting Bu, Anja Heider, Oliva Giannelli Viscardi, Lihong Chang, Sheri Simmons, Anthony Almada, Christine Avena, Tye Jensen, Raja Dhir, Ismail Ogulur, Cezmi A. Akdis   +16 more
wiley   +1 more source

RAD51 homolog (RAD51) [PDF]

Science-Business eXchange, 2008
openaire   +1 more source

Treg cells retain stable lineage commitment during pregnancy in mice after late gestation inflammatory challenge

Immunology &Cell Biology, Volume 104, Issue 3, Page 276-311, March 2026.
In this study, we used Foxp3‐fatemapping mice to examine the cell lineage stability of Treg cells in pregnancy. Ex‐Foxp3 cells were identified in gestational tissues. However, Treg cells retained lineage stability with no increased ex‐Foxp3 generation, regardless of inflammatory challenges that induce preterm birth.
Kerrie L Foyle, Ella S Green, Jessie R Walker‐Rogers, Ha M Tran, David M Olson, Lachlan M Moldenhauer, Sarah A Robertson   +6 more
wiley   +1 more source

Polo‐like kinases and UV‐induced skin carcinogenesis: What we know and what's next

Photochemistry and Photobiology, Volume 102, Issue 2, Page 276-289, March/April 2026.
The polo‐like kinase (PLK) family plays distinct and critical roles in the regulation of cell cycle progression, and its dysregulation has been implicated in various cancers. Ultraviolet (UV) radiation is a well‐established environmental factor in the development of skin cancer.
Tanya Jaiswal, Durdana Muntaqua, Gagan Chhabra, Nihal Ahmad   +3 more
wiley   +1 more source

Rad51 Recombinase and Recombination Mediators [PDF]

Journal of Biological Chemistry, 2003
Patrick, Sung, Lumir, Krejci, Stephen, Van Komen, Michael G, Sehorn   +3 more
openaire   +2 more sources

RAD51 Gene [PDF]

, 2020
openaire   +1 more source

A phase 2, open-label, multi-center study of amuvatinib in combination with platinum etoposide chemotherapy in platinumrefractory small cell lung cancer patients [PDF]

, 2017
Azab, Mohammad, Byers, Lauren Averett, Camidge, Daivd Ross, Cardnell, Robert J, Fujimoto, Junya, Ghandi, Jitendra, Horn, Leora, Kloecker, Goetz, Krzakowski, Maciej, Owonikoko, Taofeek, Taverna, Pietro, Waqar, Saiama Naheed   +11 more
core   +2 more sources

Cryo-electron microscopic visualization of RAD51 filament assembly and end-capping by XRCC3-RAD51C-RAD51D-XRCC2. [PDF]

Science
Greenhough LA, Galanti L, Liang CC, Boulton SJ, West SC.   +4 more
europepmc   +1 more source

miR-181d coordinates homologous recombination and anti-tumor immune responses in glioblastoma. [PDF]

iScience
Singh G, Singh S, Mohapatra I, Hou J, Ni A, Barik D, Zheng H, Kim S, Sharma M, Lawler S, Vasudevan S, Kokkoli E, Sarangi S, Elinzano H, Wong ET, Martinez-Moreno M, Gokaslan Z, El-Deiry W, Chen CC.   +18 more
europepmc   +1 more source