Results 171 to 180 of about 27,541 (198)
Some of the next articles are maybe not open access.
Identification and characterization of rad51 of Pneumocystis
Gene, 2007Rad51, a eukaryotic homolog of RecA, is an important protein involved in DNA recombination and repair. We have characterized rad51 of Pneumocystis carinii and Pneumocystis murina. rad51 is a single copy gene that encodes a 1.2 kb mRNA, which contains an open reading frame encoding 343 amino acids.
Geetha, Kutty, Joseph A, Kovacs
openaire +2 more sources
Crystal structure of a Rad51 filament
Nature Structural & Molecular Biology, 2004Rad51, the major eukaryotic homologous recombinase, is important for the repair of DNA damage and the maintenance of genomic diversity and stability. The active form of this DNA-dependent ATPase is a helical filament within which the search for homology and strand exchange occurs.
Adam B, Conway +6 more
openaire +2 more sources
RAD51, genomic stability, and tumorigenesis
Cancer Letters, 2005Genomic instability is characteristic of malignant cells, and a strong correlation exists between abnormal karyotype and tumorigenicity. Increased expression of the homologous recombination and DNA repair protein Rad51 has been reported in immortalized cell lines and multiple primary tumor cell types which could alter recombination pathways to ...
openaire +2 more sources
RAD51 Paralogs and RAD51 Paralog Complexes BCDX2 and CX3 Interact with BRCA2
Homologous recombination (HR) is an important mechanism for repairing DNA double-strand breaks (DSBs) and preserving genome integrity. Pathogenic mutations in the HR proteins BRCA2 and the RAD51 paralogs predispose individuals to breast, ovarian, pancreatic, and prostate cancer.Jacob G Thrasher +4 more
openaire +2 more sources
INVESTIGAZIONE DELL’INTERAZIONE BRCA2-RAD51
La Chimica e l'IndustriaThis research project aimed at elucidating the BRCA2-RAD51 interaction integrating computational and experimental approaches. Obtained results offer new mechanistic insights into how BRCA2 recruits RAD51 in the cytosol.
openaire +2 more sources
Efficient embryonic homozygous gene conversion via RAD51-enhanced interhomolog repair
Cell, 2021Jonathan J Wilde +2 more
exaly
The Rad51 paralog complex Rad55-Rad57 acts as a molecular chaperone during homologous recombination
Molecular Cell, 2021Upasana Roy, Youngho Kwon, Lea Marie
exaly
RAD51 Gene Family Structure and Function
Annual Review of Genetics, 2020Braulio Bonilla +2 more
exaly