Gadolinium nanoparticles and contrast agent as radiation sensitizers [PDF]
Physics in Medicine and Biology, 2015 The goal of the present study was to evaluate and compare the radiosensitizing properties of gadolinium nanoparticles (NPs) with the gadolinium contrast agent (GdCA) Magnevist(®) in order to better understand the mechanisms by which they act as radiation sensitizers. This was determined following either low energy synchrotron irradiation or high energy
Taupin, F. +12 more
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The future potential of Annona muricata L. extract and its bioactive compounds as radiation sensitizing agent: proposed mechanisms based on a systematic review [PDF]
Journal of Herbmed Pharmacology, 2021 Despite technological advances in cancer treatment, especially in radiotherapy, many efforts are being made in improving cancer cell radio-sensitivity to increase therapeutic ratio and overcome cancer cell radio-resistance. In the present review, we evaluated the anticancer mechanism of Annona muricata L. (AM) leaves extract and its bioactive compounds
David Andi Wijaya +8 more
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Surgical adjuvant therapy in colon carcinoma: A human tumor spheroid model for evaluating radiation sensitizing agents [PDF]
Cancer, 1981 HT-29 human colon tumor cells growing as spheroids have been evaluated as a model system for measuring the response of human colon tumor cell to antineoplastic agents. HT-29 cells have been capacity to form spheroids up to 1 mm or more in diameter when grown in spinner culture.
R M, Barone +4 more
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Selenium-Curcumin-PEG Nanoparticles Radiosensitization for Intensity-Modulated Radiation Therapy of Lung Tumor Cells: In Vitro Synergistic Combination Therapy [PDF]
Journal of Biomedical Physics and EngineeringBackground: Lung cancer is a leading cause of cancer-related mortality worldwide, underscoring the need for the development of more effective treatment strategies. Radiotherapy (RT), particularly intensity-modulated radiation therapy (IMRT), has enhanced
Farid Mortazavi +9 more
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Dinitroazetidines Are a Novel Class of Anticancer Agents and Hypoxia-Activated Radiation Sensitizers Developed from Highly Energetic Materials [PDF]
Cancer Research, 2012 Abstract In an effort to develop cancer therapies that maximize cytotoxicity, while minimizing unwanted side effects, we studied a series of novel compounds based on the highly energetic heterocyclic scaffold, dinitroazetidine. In this study, we report the preclinical validation of 1-bromoacetyl-3,3-dinitroazetidine (ABDNAZ), a ...
Shoucheng, Ning +5 more
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Evaluating the Radiosensitization Effect of Hydroxyapatite Nanoparticles on Human Breast Adenocarcinoma Cell Line and Fibroblast [PDF]
Iranian Journal of Medical Sciences, 2020 Background: Nanohydroxyapatite (nHAP) exhibit anti-proliferative effects on various cancer cells. However, to date, there are only a few studies on the radiosensitization effect of nHAP.
Mitra Soleimani +3 more
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Application of Carbon Ion and Its Sensitizing Agent in Cancer Therapy: A Systematic Review
Frontiers in Oncology, 2021 Carbon ion radiation therapy (CIRT) is the most advanced radiation therapy (RT) available and offers new opportunities to improve cancer treatment and research.
Xiaolin Wang +6 more
doaj +1 more source
EPIGENETIC MECHANISMS OF SOY ISOFLAVONES IN PROSTATE CANCER TREATMENT
Sabiad, 2022 Soy intake has been associated with a lower risk of prostate cancer. Soybeans contain isoflavones, genistein, daidzein and glycitein, which have shown anti-cancer effects in cell culture and animal studies.
Ömer Küçük
doaj +1 more source
Cancer Nanotechnology, 2022 Background To enhance the performance of radiotherapy, emerging nanoparticles that can professionally enhance X-ray irradiation to destruct cancer cells are extremely necessary.
Mahshid Mohammadian +2 more
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