Results 21 to 30 of about 22,923 (306)

Low dose novel PARP-PI3K inhibition via nanoformulation improves colorectal cancer immunoradiotherapy

Materials Today Bio, 2020
Multimodal therapy is often used in oncology to overcome dosing limitations and chemoresistance. Recently, combination immunoradiotherapy has shown great promise in a select subset of patients with colorectal cancer (CRC).
M.R. Landry, A.N. DuRoss, M.J. Neufeld, L. Hahn, G. Sahay, R. Luxenhofer, C. Sun   +6 more
doaj   +1 more source

Targeting Cellular Metabolism With CPI-613 Sensitizes Pancreatic Cancer Cells to Radiation Therapy

Advances in Radiation Oncology, 2023
Purpose: Local tumor progression is a cause of significant morbidity and mortality in patients with pancreatic ductal adenocarcinoma (PDAC) with surgically unresectable disease.
Husain Yar Khan, PhD, Mandana Kamgar, MD, Amro Aboukameel, MS, Sahar Bannoura, MS, Brian Y. Chung, PhD, Yiwei Li, MD, Mohammed Najeeb Al Hallak, MD, Philip A. Philip, MD, PhD, Susan Tsai, MD, Sanjeev Luther, MBA, William A. Hall, MD, Asfar S. Azmi, PhD   +11 more
doaj   +1 more source

First examples of pyran based colorants as sensitizing agents of p-Type Dye-Sensitized solar cells [PDF]

, 2017
Three different pyran based dyes were synthesized and tested for the first time as photosensitizers of NiO based p-type dye-sensitized solar cells (p-DSSC).
Bonomo, Matteo, Carella, Antonio, Centore, Roberto, Di Carlo, Aldo, Dini, Danilo   +4 more
core   +1 more source

Does particle radiation have superior radiobiological advantages for prostate cancer cells? A systematic review of in vitro studies

European Journal of Medical Research, 2022
Background Charged particle beams from protons to carbon ions provide many significant physical benefits in radiation therapy. However, preclinical studies of charged particle therapy for prostate cancer are extremely limited.
Tian-Qi Du, Ruifeng Liu, Qiuning Zhang, Hongtao Luo, Yanliang Chen, Mingyu Tan, Qian Wang, Xun Wu, Zhiqiang Liu, Shilong Sun, Kehu Yang, Jinhui Tian, Xiaohu Wang   +12 more
doaj   +1 more source

Cross-sensitivity to DNA-damaging agents in radiation-sensitive mutants of murine leukemia cells. [PDF]

Journal of Radiation Research, 1986
Two independently isolated radiation-sensitive mutants, M10 and LX830, of mouse L5178Y cells were compared for their sensitivity to various DNA-damaging agents. These two mutants share hypersensitivity to gamma rays, bleomycin, arabinofuranosyl cytosine (Ara-C) and aphidicolin.
K, Sato, A, Ito, N, Hieda-Shiomi, T, Shiomi, H, Hama-Inaba   +4 more
openaire   +2 more sources

Chloroquine plays a cell-dependent role in the response to treatment of pancreatic adenocarcinoma [PDF]

, 2018
In this study, our aim is to assess the role played by autophagy and its inhibition in the different PDAC cellular compartments, and its involvement in chemo-resistance using primary human pancreatic cancer-derived cells (PCC) and Cancer Associated ...
Bintz, Jennifer, Fanale, Daniele, Gayet, Odile, Iovanna, Juan Lucio, Molejon, Maria Ines, Soubeyran, Philippe, Swayden, Mirna   +6 more
core   +1 more source

Efficiency Comparison between Radiotherapy Alone And In The Presence of Radio- or Photo- Sensitizers on Viability of DFW and HT29 Cell Lines: From Simulations to Experimental Results [PDF]

Iranian Journal of Medical Physics
Introduction: Radiotherapy (RT) is a conventional cancer treatment which address needs of most cancerous patients. However, toxicity of high X-ray energies increases side effects to the normal tissues.
Farideh Hosseini, Nadia Naghavi, Ameneh Sazgarnia, Atefeh Vejdani Noghreiyan   +3 more
doaj   +1 more source

Small inhibitor of Bcl-2, HA14-1, selectively enhanced the apoptotic effect of cisplatin by modulating Bcl-2 family members in MDA-MB-231 breast cancer cells [PDF]

, 2010
Inhibition or downregulation of Bcl-2 represents a new therapeutic approach to by-pass chemoresistance in cancer cells. Therefore, we explored the potential of this approach in breast cancer cells.
A Letai, AK Zimmermann, Cagri Bodur, D Moon, D Tian, Dilek Telci, DJ Stewart, Elif Damla Arisan, F Manero, FA Sinicrope, Huveyda Basaga, IJ Enyedy, J An, J Chen, J Skommer, J Yu, JC Reed, JD Lickliter, JI Okani, JL Wang, JL Wang, L Chen, L Ming, L Oliver, M Milella, Ozgur Kutuk, RK Srivastava, SW Lowe, Tugsan Tezil, X Pei, X Wang, XY Pei, Y Ling, Y Su, Z Liu   +34 more
core   +1 more source

Potentiation of the abscopal effect by modulated electro-hyperthermia in locally advanced cervical cancer patients [PDF]

, 2020
Background: A Phase III randomized controlled trial investigating the addition of modulated electro-hyperthermia (mEHT) to chemoradiotherapy for locally advanced cervical cancer patients is being conducted in South Africa (Human Research Ethics Committee
Ayeni, Olusegun, Baeyens, Ans, Kotzen, Jeffrey, Minnaar, Carrie Anne, Vangu, Mboyo-Di-Tamba   +4 more
core   +2 more sources

The simultaneous effect of valproic acid and gamma radiation on telomerase activity and bax and Bcl-2 protein levels in MCF-7 breast cancer cell line [PDF]

, 2015
Background: Breast cancer is one of the most prevalent types of cancer. Factors such as ionizing radiation and chemotherapeutic agents can trigger apoptosis and cancer cell death.
Asadi, J., Binabaj, M.M., Hosseini, S.A., Khoshnazar, A.K.   +3 more
core   +1 more source