Results 81 to 90 of about 28,129 (278)

Probing the Effects of Retinoblastoma Binding Protein 6 (RBBP6) Knockdown on the Sensitivity of Cisplatin in Cervical Cancer Cells

Cells
Cervical cancer is a major cause of death in women despite the advancement of current treatment modalities. The conventional therapeutic agent, cisplatin (CCDP), is the standard treatment for CC; however, resistance often develops due to the cancer’s ...
Harshini Mehta, Melvin Anyasi Ambele, Ntlotlang Mokgautsi, Pontsho Moela   +3 more
doaj   +1 more source

Insulin-sensitizing agents--thiazolidinediones (glitazones).

, 2002
Insulin resistance is a fundamental feature of type 2 diabetes and is also associated with increased cardiovascular risk. The thiazolidinediones are insulin sensitizing agents which improve insulin resistance by combining with an intranuclear hormone ...
Barnett, Anthony
core  

Sensitizing potential of enzymatically cross-linked peanut proteins in a mouse model of peanut allergy.

, 2014
SCOPE: The cross-linking of proteins by enzymes to form high-molecular-weight protein, aggregates can be used to tailor the technological or physiological functionality of food products.
IRAS RATIA1, Smit, Joost, Sub IRAS Tox ITX (immunotoxicologie), Risk Assessment of Toxic and Immunomodulatory Agents   +3 more
core   +1 more source

Understanding cisplatin resistance using cellular models [PDF]

, 2007
Many mechanisms of cisplatin resistance have been proposed from studies of cellular models of resistance including changes in cellular drug accumulation, detoxification of the drug, inhibition of apoptosis and repair of the DNA adducts.
Davey, M, Davey, Mary W., Davey, Mary W, Stordal, B, Britta Stordal, Mary Davey, Stordal, Britta   +6 more
core   +1 more source

Selenium Nanomaterials for Wound Healing: Synergistic Strategies from Anti‐Infection to Tissue Regeneration

Advanced NanoBiomed Research, EarlyView.
Selenium nanoparticles (SeNPs) are emerging as multifunctional platforms for wound healing, integrating antimicrobial, anti‐inflammatory, and proregenerative activities. This review summarises key mechanisms and recent advances in SeNP‐enabled composite dressings, immunomodulatory nanocomposites, microenvironment‐responsive hydrogels, photothermal and ...
Yangxia Chen, Xiaoshuang Liang, Sirui Li, Shuoshan Li, Wei Liu, Yingping Lin, Siqi Li, Zehang Zhang, Judun Zheng, Tianfeng Chen, Rongyi Chen   +10 more
wiley   +1 more source

ALA-RDT in GBM: protocol of the phase I/II dose escalation trial of radiodynamic therapy with 5-Aminolevulinic acid in patients with recurrent glioblastoma

Radiation Oncology
Background Despite improvements in surgical as well as adjuvant therapies over the last decades, the prognosis for patients with glioblastoma remains poor.
Niklas Benedikt Pepper, Hans Theodor Eich, Michael Müther, Michael Oertel, Stephan Rehn, Dorothee Cäcilia Spille, Walter Stummer   +6 more
doaj   +1 more source

Radiation Therapy for Liver Tumors: Future Directions

, 2017
Radiation therapy for liver tumors has changed dramatically in the last few decades, from purely palliative to now potentially curative in the form of stereotactic body radiation therapy (SBRT).
Eric A. Mellon, Mellon, Eric A, Hoffe, Sarah E, Sarah E. Hoffe, Murimwa, Gilbert, Gilbert Murimwa   +5 more
core   +1 more source

Radiosensitizers in hepatocellular carcinoma

, 2011
Most hepatocellular carcinoma (HCC) patients present with locally advanced disease with a risk of development of intrahepatic or extrahepatic metastases.
이익재, 성진실
core   +1 more source

Efficacy, safety and cost‐effectiveness of CAR‐T therapy

British Journal of Clinical Pharmacology, EarlyView.
CAR T‐cells demonstrate high efficacy in blood cancers, including ALL, MM and DLBCL. Innovations target solid tumours despite challenges such as antigen escape. Combination therapies enhance the delivery and infiltration of CAR T cells. Toxicity, cost and resistance remain major barriers to clinical use.
Emina Karahmet Sher, Amina Džidić‐Krivić, Emma Pinjic, Nejra Selak, Kanita Omerbasic, Alexandar Chupin, Andrej Belancic, Almir Fajkic   +7 more
wiley   +1 more source

Opportunities and Challenges in the Era of Molecularly Targeted Agents and Radiation Therapy [PDF]

, 2013
The first annual workshop for preclinical and clinical development of radiosensitizers took place at the National Cancer Institute on August 8-9, 2012. Radiotherapy is one of the most commonly applied and effective oncologic treatments for solid tumors ...
성진실
core   +1 more source