Results 1 to 10 of about 890,751 (309)

Data of radiation damage on selenomethionine-substituted single-domain substrate-binding protein [PDF]

open access: yesData in Brief
Radiation damage is an inherent issue in X-ray crystallography. It not only damages macromolecular crystals, which lowers the quality of the diffraction intensity, but results in inaccurate structural information.
Ki Hyun Nam
doaj   +2 more sources

Mouse Slfn8 and Slfn9 genes complement human cells lacking SLFN11 during the replication stress response

open access: yesCommunications Biology, 2023
The Schlafen (SLFN)11 gene has been implicated in various biological processes such as suppression of HIV replication, replication stress response, and sensitization of cancer cells to chemotherapy.
Erin Alvi   +7 more
doaj   +1 more source

Isolation of human and murine hematopoietic stem cells for DNA damage and DNA repair assays

open access: yesSTAR Protocols, 2021
Summary: Hematopoietic stem and progenitor cells (HSPCs) reside in the bone marrow and supply blood cells. Efficient methods for isolation of HSPCs are required. Here, we present protocols for the isolation of human and murine HSPCs using manual and FACS-
Alfredo Rodríguez   +5 more
doaj   +1 more source

Modifying Radiation Damage [PDF]

open access: yesCurrent Drug Targets, 2010
Radiation leaves a fairly characteristic footprint in biological materials, but this is rapidly all but obliterated by the canonical biological responses to the radiation damage. The innate immune recognition systems that sense "danger" through direct radiation damage and through associated collateral damage set in motion a chain of events that, in a ...
Kwanghee, Kim, William H, McBride
openaire   +2 more sources

Insufficient ablation promotes the metastasis of residual non-small cell lung cancer (NSCLC) cells via upregulating carboxypeptidase A4

open access: yesInternational Journal of Hyperthermia, 2021
Background Thermal ablation is a potentially curative therapy for early-stage non-small cell lung cancer (NSCLC). Early recurrence after thermal ablation necessitates our attention.
Peng Yan   +9 more
doaj   +1 more source

Radiation Damage on Selenomethionine-Substituted Single-Domain Substrate-Binding Protein

open access: yesCrystals, 2023
Radiation damage is an inherent challenge in macromolecular crystallography (MX). This diminishes the diffraction quality and also compromises the accuracy of the crystal structure.
Ki Hyun Nam
doaj   +1 more source

A Meta-Analysis of the Effects of High-LET Ionizing Radiations in Human Gene Expression

open access: yesLife, 2021
The use of high linear energy transfer (LET) ionizing radiation (IR) is progressively being incorporated in radiation therapy due to its precise dose localization and high relative biological effectiveness.
Theodora-Dafni Michalettou   +5 more
doaj   +1 more source

Research progress on the characterization of irradiation damage defects and performance control of titanium alloy

open access: yesJournal of Aeronautical Materials, 2022
Under the high-energy particle impingement and cascade effect, different types of radiation damage defects occur in metals. The aggregation and evolution of radiation damage defects can lead to the destruction of the internal structural stability and the
YE Yongqiang   +4 more
doaj   +1 more source

Cooperation of the ATM and Fanconi Anemia/BRCA Pathways in Double-Strand Break End Resection

open access: yesCell Reports, 2020
Summary: Cells deficient in ataxia telangiectasia mutated (ATM) are hypersensitive to ionizing radiation and other anti-cancer agents that induce double-strand DNA breaks. ATM inhibitors may therefore sensitize cancer cells to these agents.
Mu-Yan Cai   +9 more
doaj   +1 more source

Circ-CPSF1 Worsens Radiation-Induced Oxidative Stress Injury in Caenorhabditis elegans

open access: yesBiomolecules, 2023
Radioactive substances have been used in various aspects in daily life. However, high-energy radiation could cause environmental problems, which would damage the human body.
Jing Yuan   +8 more
doaj   +1 more source

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