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Radiation induced DNA damage responses [PDF]
Radiation Protection Dosimetry, 2006 The amazing feature of ionising radiation (IR) as a DNA damaging agent is the range of lesions it induces. Such lesions include base damage, single strand breaks (SSBs), double strand breaks (DSBs) of varying complexity and DNA cross links.
Jeggo, Penny, Löbrich, Markus
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Data of radiation damage on selenomethionine-substituted single-domain substrate-binding protein [PDF]
Data in BriefRadiation damage is an inherent issue in X-ray crystallography. It not only damages macromolecular crystals, which lowers the quality of the diffraction intensity, but results in inaccurate structural information.
Ki Hyun Nam
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Communications Biology, 2023 The Schlafen (SLFN)11 gene has been implicated in various biological processes such as suppression of HIV replication, replication stress response, and sensitization of cancer cells to chemotherapy.
Erin Alvi +7 more
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Isolation of human and murine hematopoietic stem cells for DNA damage and DNA repair assays
STAR Protocols, 2021 Summary: Hematopoietic stem and progenitor cells (HSPCs) reside in the bone marrow and supply blood cells. Efficient methods for isolation of HSPCs are required. Here, we present protocols for the isolation of human and murine HSPCs using manual and FACS-
Alfredo Rodríguez +5 more
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Modifying Radiation Damage [PDF]
Current Drug Targets, 2010 Radiation leaves a fairly characteristic footprint in biological materials, but this is rapidly all but obliterated by the canonical biological responses to the radiation damage. The innate immune recognition systems that sense "danger" through direct radiation damage and through associated collateral damage set in motion a chain of events that, in a ...
Kwanghee, Kim, William H, McBride
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International Journal of Hyperthermia, 2021 Background Thermal ablation is a potentially curative therapy for early-stage non-small cell lung cancer (NSCLC). Early recurrence after thermal ablation necessitates our attention.
Peng Yan +9 more
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Radiation Damage on Selenomethionine-Substituted Single-Domain Substrate-Binding Protein
Crystals, 2023 Radiation damage is an inherent challenge in macromolecular crystallography (MX). This diminishes the diffraction quality and also compromises the accuracy of the crystal structure.
Ki Hyun Nam
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Radiation damage and yield strength calculations in the pressure vessel of WWER-1000 reactor and sensitivity analysis of neutron spectrum on the shield of vessel [PDF]
مجله علوم و فنون هستهای, 2021 Radiation damage calculation is very important for estimating the lifetime of nuclear power plant instruments. The purpose of the present study is to evaluate the sensitivity of the damage values to the neutron group energy, where the neutron flux rate ...
E. Moslemi-Mehni +3 more
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A Meta-Analysis of the Effects of High-LET Ionizing Radiations in Human Gene Expression
Life, 2021 The use of high linear energy transfer (LET) ionizing radiation (IR) is progressively being incorporated in radiation therapy due to its precise dose localization and high relative biological effectiveness.
Theodora-Dafni Michalettou +5 more
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Journal of Aeronautical Materials, 2022 Under the high-energy particle impingement and cascade effect, different types of radiation damage defects occur in metals. The aggregation and evolution of radiation damage defects can lead to the destruction of the internal structural stability and the
YE Yongqiang +4 more
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