Results 11 to 20 of about 838,261 (308)

A Brain-Penetrating Hsp90 Inhibitor NXD30001 Inhibits Glioblastoma as a Monotherapy or in Combination With Radiation

Frontiers in Pharmacology, 2020
Glioblastoma multiforme (GBM) is a highly heterogeneous disease, which is initiated and sustained by various molecular alterations in an array of signal transduction pathways.
Hao Chen, Hao Chen, Yuanying Gong, Yufang Ma, Reid C. Thompson, Jialiang Wang, Zhixiang Cheng, Zhixiang Cheng, Lixia Xue   +8 more
doaj   +1 more source

miRNA‐218‐5p increases cell sensitivity by inhibiting PRKDC activity in radiation‐resistant lung carcinoma cells

Thoracic Cancer, 2021
Background Non‐small cell lung carcinoma (NSCLC) is a malignancy with the highest mortality rate. Currently, surgery combined with radiotherapy is the first choice in the clinical treatment of lung carcinoma (LC); however, long‐term radiotherapy leads to
Xiaoke Chen, Yuanyuan Xu, Long Jiang, Qiang Tan   +3 more
doaj   +1 more source

Resonant properties of an impedance monopole located on a perfectly conducting rectangular screen [PDF]

Радиофизика и электроника, 2020
Subject and Purpose. A resonant monopole of an electrical length 0.2 £ l / l £ 0.3 mounted on an infinite, perfectly conducting plane or on a rectangular, perfectly conducting screen is considered.
N.P. Yeliseyeva, S.L. Berdnik, V.A. Katrich   +2 more
doaj   +1 more source

Influence of ionizing radiation on the parameters of p-channel MOS transistors

Весці Нацыянальнай акадэміі навук Беларусі: Серыя фізіка-тэхнічных навук, 2023
The results of experimental studies of the influence of gamma radiation Co60 on the basic parameters of silicon epitaxial-planar p-channel MOSFET transistors under different electrical modes are presented.
Yu. V. Bogatyrev, D. A. Aharodnikau, S. B. Lastovsky, A. V. Ket’ko, M. M. Krechko, S. V. Shpakovsky, P. V. Rubanov, G. A. Protopopov, P. A. Chubunov   +8 more
doaj   +1 more source

Collisionless reconnection using Alfvén wave radiation resistance [PDF]

, 1998
Patchy magnetic reconnection involves transient field-aligned current filaments. The spatial localization, transient time-dependence, and orientation of these current filaments means they must radiate torsional Alfvén waves. Radiation of wave energy does
Bellan, P. M.
core   +1 more source

Radiation resistant plastic scintillator with 4,4′-di-tert-butylbiphenyl [PDF]

Ядерна фізика та енергетика
The article considers the possibility of creating a radiation-resistant plastic scintillator based on polystyrene using a dialkyl derivative of biphenyl – 4,4′-di-tert-butylbiphenyl.
O. V. Yelisieieva, D. A. Yelisieiev, Yu. О. Нurkalenko, P. М. Zhmurin, V. D. Alekseev   +4 more
doaj   +1 more source

Genomic stability in response to high versus low linear energy transfer radiation in Arabidopsis thaliana. [PDF]

, 2014
Low linear energy transfer (LET) gamma rays and high LET HZE (high atomic weight, high energy) particles act as powerful mutagens in both plants and animals.
Britt, Anne B, Conklin, Phillip A, Friesner, Joanna D, Huefner, Neil D, Yoshiyama, Kaoru   +4 more
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The Mitochondrial Citrate Carrier (SLC25A1) Sustains Redox Homeostasis and Mitochondrial Metabolism Supporting Radioresistance of Cancer Cells With Tolerance to Cycling Severe Hypoxia

Frontiers in Oncology, 2018
Pronounced resistance of lung cancer cells to radiotherapy and chemotherapy is a major barrier to successful treatment. Herein, both tumor hypoxia and the upregulation of the cellular antioxidant defense systems observed during malignant progression can ...
Julian Hlouschek, Christine Hansel, Verena Jendrossek, Johann Matschke   +3 more
doaj   +1 more source

The Effect of Silane Coupling Agent on the Texture and Properties of In Situ Synthesized PI/SiO₂ Nanocomposite Film

Nanomaterials, 2022
PI/SiO2 composite films have been prepared by using in situ polymerization. The influences of the dosage of silane coupling agent (KH-560) on the structure and performance of PI/SiO2 composite film have been investigated.
Jindong Huang, Hong Chen, Guanglu Zhang, Xiaowei Fan, Juncheng Liu   +4 more
doaj   +1 more source

DNA methylation changes following DNA damage in prostate cancer cells

Epigenetics, 2019
Many cancer therapies operate by inducing double-strand breaks (DSBs) in cancer cells, however treatment-resistant cells rapidly initiate mechanisms to repair damage enabling survival.
Laura P. Sutton, Sarah A. Jeffreys, Jessica L. Phillips, Phillippa C. Taberlay, Adele F. Holloway, Mark Ambrose, Ji-Hoon E. Joo, Arabella Young, Rachael Berry, Marketa Skala, Kate H. Brettingham-Moore   +10 more
doaj   +1 more source