Results 41 to 50 of about 156,482 (292)

LDAcoop: Integrating non‐linear population dynamics into the analysis of clonogenic growth in vitro

Molecular Oncology, EarlyView.
Limiting dilution assays (LDAs) quantify clonogenic growth by seeding serial dilutions of cells and scoring wells for colony formation. The fraction of negative wells is plotted against cells seeded and analyzed using the non‐linear modeling of LDAcoop.
Nikko Brix, Daniel Samaga, Katharina Gehr, Benedek Dankó, Mohamed Schumann, Guido Drexler, Ahmed Alnatsha, Georg Beyer, Ujjwal Mahajan, Martin Selmansberger, Julia Mayerle, Claus Belka, Horst Zitzelsberger, Kirsten Lauber   +13 more
wiley   +1 more source

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

Molecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

Simultaneous solution of Kompaneets equation and Radiative Transfer equation in the photon energy range 1 - 125 KeV

, 2010
Radiative transfer equation in plane parallel geometry and Kompaneets equation is solved simultaneously to obtain theoretical spectrum of 1-125 KeV photon energy range.
A. Peraiah, Arons, B.A. Varghese, Burigana, Canfield, Chandrasekhar, Czerny, Deufel, Done, Dreicer, Dubinov, Evans, George, Ghisellini, Ghisellini, Grant, Grant, Haardt, Hua, Illarionov, Illarionov, Katz, Kershaw, Kompaneets, Larsen, Levich, Lightman, M. Srinivasa Rao, Madej, Madej, Madej, Madej, Magadziarz, Majczyna, Matt, Miyamoto, Nandra, Nishimura, Peraiah, Peraiah, Pomraning, Pounds, Prasad, Rogers, Rybieki, Shapiro, Sunyaev, Sunyaev, White, Zeldovich   +49 more
core   +1 more source

Targeted modulation of IGFL2‐AS1 reveals its translational potential in cervical adenocarcinoma

Molecular Oncology, EarlyView.
Cervical adenocarcinoma patients face worse outcomes than squamous cell carcinoma counterparts despite similar treatment. The identification of IGFL2‐AS1's differential expression provides a molecular basis for distinguishing these histotypes, paving the way for personalized therapies and improved survival in vulnerable populations globally.
Ricardo Cesar Cintra, Lucca Paolo Hsu Helmich, Daniel Rodrigues de Bastos, Laura Sichero, Patrícia Savio de Araujo‐Souza, Fabio Passetti, Luisa Lina Villa   +6 more
wiley   +1 more source

On the efficiency of the maximum cross section method in radiation transport theory [PDF]

Компьютерные исследования и моделирование, 2013
We consider two versions of the maximum cross section method for the solutions of the stationary equation of radiative transfer in dimensional inhomogeneous medium.
Igor Vasilievich Prokhorov, Anton Sergeevich Zhuplev   +1 more
doaj   +1 more source

Radiative transfer in moving media II. Solution of the radiative transfer equation in axial symmetry

, 2005
A new method for the formal solution of the 2D radiative transfer equation in axial symmetry in the presence of arbitrary velocity fields is presented.
Boissé, Cannon, D. Korčáková, Domiciano de Souza, Dullemond, Dykema, Gruschinske, Hauschildt, J. Kubát, Jackson, Kneer, Krticka, Kubát, Kubát, Kubát, Kunasz, Kunasz, Mihalas, Mihalas, Noerdlinger, Papkalla, Richling, Steinacker, van Noort   +23 more
core   +1 more source

Entrapment: an important mechanism to explain the shortwave 3D radiative effect of clouds [PDF]

, 2019
Several mechanisms have previously been proposed to explain differences between the shortwave reflectance of realistic cloud scenes computed using the 1D independent column approximation (ICA) and 3D solutions of the radiative transfer equation. When the
Barker, Howard W., Fielding, Mark D., Hogan, Robin J., Schäfer, Sophia A. K., Villefranque, Najda   +4 more
core   +2 more sources

EDNRB‐dependent endothelin signaling reduces proliferation and promotes proneural‐to‐mesenchymal transition in gliomas

Molecular Oncology, EarlyView.
Glioma cells mainly express the endothelin receptor EDNRB, while EDNRA is restricted to a perivascular tumor subpopulation. Endothelin signaling reduces glioma cell proliferation while promoting migration and a proneural‐to‐mesenchymal transition associated with poor prognosis. This pathway activates Ca2+, K+, ERK, and STAT3 signalings and is regulated
Donovan Pineau, Leonor Garcia, Hugo Arnold, Antonija Hanžek, Maialen Arrieta, Laurent R Gauthier, Christine Granotier‐Beckers, François D Boussin, Amaury Herbet, Marie Hautière, Valentin Asei‐Ceschino, Clémentin Jacques, Laura Brard, Thomas Harnois, Valérie Coronas, Bruno Constantin, Aurélien Chatelier, Jean Chemin, Serge Urbach, Martial Seveno, Szimonetta Hideg, Chantal Ripoll, Kasandra Aguilar‐Cázarez, Min Zheng, Guo‐Hao Huang, Sheng‐Qing Lv, Lei Zhang, Philippe Rondard, Laurent Prezeau, Jean‐Philippe Pin, Hugues Duffau, Luc Bauchet, Valérie Rigau, Franck Denat, Charles Truillet, Didier Boquet, Jean‐Philippe Hugnot   +36 more
wiley   +1 more source

Cell‐cycle‐specific lesion evolution rather than inhibition of double‐strand‐break repair underpins cisplatin radiosensitization

Molecular Oncology, EarlyView.
We analyze cisplatin–DNA adducts (CDAs) and double‐strand breaks (DSBs) in a cell‐cycle‐dependent manner. We find that CDAs form similarly across all cell cycle phases. DSBs arise only in S‐phase. CDAs might not directly impair DSB repair, but S‐phase DSB lesions evolve in the presence of CDAs and disrupt repair in G2, also causing radiosensitization ...
Ye Qiu, Xixi Lin, Emil Mladenov, Veronika Mladenova, Jürgen Thomale, Ali Sak, Yao Wang, Yunxuan Deng, Eleni Gkika, Martin Stuschke, George Iliakis   +10 more
wiley   +1 more source

Mesoscopic lattice Boltzmann model for radiative heat transfer in graded-index media

Physical Review Research, 2022
Convection, conduction, and thermal radiation are the three mechanisms of heat transfer in nature. The lattice Boltzmann model (LBM) has already achieved great success in dealing with convection and conduction problems.
Xiaochuan Liu, Si Wu, Keyong Zhu, Yuepei Cai, Yong Huang   +4 more
doaj   +1 more source