Results 1 to 10 of about 13,286 (140)

Influence of Storage Temperature on Radiochemical Purity of 99mTc-Radiopharmaceuticals [PDF]

Molecules, 2018
The influence of effective room temperature on the radiochemical purity of 99mTc-radiopharmaceuticals was reported. This study was born from the observation that in the isolators used for the preparation of the 99mTc-radiopharmaceuticals the temperatures
Licia Uccelli, Alessandra Boschi, Petra Martini, Corrado Cittanti, Stefania Bertelli, Doretta Bortolotti, Elena Govoni, Luca Lodi, Simona Romani, Samanta Zaccaria, Elisa Zappaterra, Donatella Farina, Carlotta Rizzo, Melchiore Giganti, Mirco Bartolomei   +14 more
doaj   +5 more sources

Evaluation of Tetrofosmin Cold Kit Fractionation Using Alternative New Method of Quality Control for Testing Radiochemical Purity [PDF]

World Journal of Nuclear Medicine, 2022
Objective The aim of this study is to establish a method for the fractionation of tetrofosmin cold kit under different storage conditions and to optimize an alternate chromatography method from the reference method to test radiochemical purity (RCP).
Nisha Bhatia, Rakhee Vatsa, Vandana K. Dhingra, Devinder Kumar Dhawan, Vijayta Dani Chadha   +4 more
doaj   +2 more sources

Improvement of End-of-Synthesis Radiochemical Purity of ¹⁷⁷Lu-DOTA-PSMA-Ligands with Alternative Synthesis Approaches: Conversion Upswing and Side-Products Minimization [PDF]

Pharmaceutics
Background: Radiochemical purity is a key criterion for the quality of radiopharmaceuticals used in clinical practice. The joint improvement of analytical methods capable of identifying related radiochemical impurities and determining the actual ...
Anton Larenkov, Iurii Mitrofanov, Marat Rakhimov   +2 more
doaj   +2 more sources

An alternative methodology for the determination of the radiochemical purity of 11C-methionine [PDF]

EJNMMI Radiopharmacy and Chemistry, 2018
Background [11C]Methionine ([11C]MET) acts as an oncological radiopharmaceutical for measuring increased protein synthesis in brain tumours while having low uptake in normal brain an.
Javier Giglio, Gabriela Rosas, Martín Basso, Andrea Boné, Eduardo Savio, Henry Engler   +5 more
doaj   +2 more sources

Multifactorial analysis of radiochemical purity in high-activity 177Lu-labeled theranostics: impact of precursor source, 177Lu form, and production parameters [PDF]

EJNMMI Radiopharmacy and Chemistry
Background Lutetium-177 (177Lu) theranostics have revolutionized personalized cancer treatment, particularly with FDA-approved therapies like [177Lu]Lu-DOTA-TATE for neuroendocrine tumors and [177Lu]Lu-PSMA for prostate cancer.
William Hunt, Mathew Long, Usama Kamil, Sunil Kellapatha, Wayne Noonan, Peter D. Roselt, Nathan Papa, Brittany Emmerson, Michael S. Hofman, Mohammad B. Haskali   +9 more
doaj   +2 more sources

General Methods, Application Development and Related Problems of Radiochemical Purity Analysis

Journal of Isotopes, 2023
In recent years, the development of innovative radiopharmaceuticals has become a “hot spot”. In these development processes, it is crucial for researchers to createa radiochemical purity analysis method which is accurate, fast, and convenient.
YAO Jingjing;YANG Weifang;FAN Mingxuan;LU Jie
doaj   +1 more source

A Modified Method for Increasing Radiochemical Purity of I-125 for Radiopharmaceuticals

Atom Indonesia, 2023
Iodine-125 (125I) is one of the radioisotopes widely used in radiopharmaceuticals for diagnosis and therapy of various cancers. Recent reports indicate that there has been shortages in the world supply of this radioiodine isotope.
M Maiyesni, M Mujinah, D. Kurniasih, W Witarti, H Hambali, S. Febriana, I. Kambali   +6 more
doaj   +1 more source

A Review on Radiochemical Purity Analysis Methods of Radiopharmaceuticals

Journal of Isotopes, 2021
Radiopharmaceuticals means radionuclide preparations or labeled compounds for clinical diagnosis or therapeutic use. Radiochemical purity is one of the important judgment indexes to measure the quality of radiopharmaceuticals, which directly affects the ...
ZHANG Yun;YANG Liu;JIANG Hua
doaj   +1 more source

EFFECT OF THE RADIOCHEMICAL IMPURITIES OF99mTC-MIBI ON THEDIAGNOSTIC QUALITY OF THE IMAGES IN NUCLEAR MEDICINE

Anales (Asociación Física Argentina), 2021
This work analyzes the reliability of the radiochemical purity control method of 99mTc-MIBI used in nuclear medicine services and the influence of the greater presence of radiochemical impurities in the diagnostic quality of the obtained images.
N. Guisande, J. Sanchez, L. Garavaglia, S. Rozanskas, G. Dopta, K. Pertusi, V. Sanz, A. Mele, L. Illanes, C. Y. Chain   +9 more
doaj   +1 more source

Radiolabeling Technique of Silver Nanoparticles (AgNPs) with Iodine-131 Radionuclide

Atom Indonesia, 2020
Radiotherapy is an effective cancer therapy, where a certain dose of radiation is aimed specifically at target and is unaffecting to normal tissue. A selectiveradionuclide must be attached to the specific targeted organ.
U.N. Sholikhah, R.R. Syahdi, S.E. Permatasari, E. Sarmini, S Sriyono, T. Widyaningrum   +5 more
doaj   +1 more source