Results 11 to 20 of about 13,323 (173)

The Use of Low Ammonia Concentration in the Radiochemical Purity Test of [153Sm]Sm-EDTMP by Using the Thin Layer Chromatography Method [PDF]

Journal of Pure and Applied Chemistry Research, 2021
Radiochemical purity testing of [153Sm]Sm-EDTMP usually uses the Thin Layer Chromatography method. The mobile phase used is a mixture of 25% ammonia and water. However, the lowest ratio of 25% ammonia in the mobile phase is unknown.
Amal Rezka Putra, Khoirunnisa Fauziah Asyikin, Robertus Dwi Hendarto, Agus Ariyanto, Enny Lestari, Sumandi Juliyanto, Ahsanal Fikri   +6 more
doaj  

Iodine-131 labeled genistein as a potential radiotracer for breast cancer

Heliyon, 2020
Objective: Genistein is an isoflavone compound that has been proven to have anticancer activity and is capable of binding to estrogen β receptors with Selective Estrogen Receptor Modulators (SERMs) properties, and has a strong affinity to inhibit the ...
Danni Ramdhani, Eva Maria Widyasari, Maula Eka Sriyani, Quinzheilla Putri Arnanda, Hiroshi Watabe   +4 more
doaj   +1 more source

Evaluation of radiochemical purities of some radiopharmaceuticals in Shiraz Namazi teaching hospital [PDF]

Trends in Pharmaceutical Sciences, 2015
Radiopharmaceuticals are a special group of drugs since many of them are eventually prepared in the hospital and the nuclear medicine department is therfore responsible for meeting quality criteria such as sterility, radionuclide, radiochemical and ...
Hossein Sadeghpour, Mehrosadat Alavi, Majid Shahedi, Seyed Mohammad Entezarmahdi, Amirhossein Sakhteman   +4 more
doaj   +5 more sources

Preparation of 99mTc-quercetion as a labeled flavonoid and the study of its biological distribution in mice with skin tumor [PDF]

مجله علوم و فنون هسته‌ای, 2021
The aim of this study was to label quercetin as a natural flavonoid compound with technetium-99m and to study its biological distribution in different tissues of C57 mice bearing melanoma B16F10 cells for tumor diagnosis. Quercetin labeling was performed
M. Ghalbi Ahangari, M. Moridi Farimani, M. Erfani, M. Goudarzi   +3 more
doaj   +1 more source

Improved quality control of [177Lu]Lu-PSMA I&T

EJNMMI Radiopharmacy and Chemistry, 2023
Background Targeted radionuclide therapy with [177Lu]Lu-PSMA I&T (zadavotide guraxetan) has proven high efficacy and safety in treating patients with advanced prostate cancer worldwide.
Martin Kraihammer, Piotr Garnuszek, Andreas Bauman, Michael Maurin, Manuel Alejandre Lafont, Roland Haubner, Elisabeth von Guggenberg, Michael Gabriel, Clemens Decristoforo   +8 more
doaj   +1 more source

One-pot and one-step automated radio-synthesis of [18F]AlF-FAPI-74 using a multi purpose synthesizer: a proof-of-concept experiment

EJNMMI Radiopharmacy and Chemistry, 2021
Background Fibroblast activation protein (FAP) is overexpressed in the stroma of many types of cancer. [18F]AlF-FAPI-74 is a positron emission tomography tracer with high selectivity for FAP, which has already shown high accumulation within human tumors ...
Sadahiro Naka, Tadashi Watabe, Thomas Lindner, Jens Cardinale, Kenta Kurimoto, Melissa Moore, Mitsuaki Tatsumi, Yuriko Mori, Eku Shimosegawa, Frank Valla, Hiroki Kato, Frederik L. Giesel   +11 more
doaj   +1 more source

The Semi-automatic Synthesis of 18F-fluoroethyl-choline by Domestic FDG Synthesizer

Journal of Isotopes, 2016
As an important complementary imaging agent for 18F-FDG, 18F-fluoroethyl-choline (18F-FECH) has been demonstrated to be promising in brain and prostate cancer imaging.
ZHOU Ming, ZHANG Xiao-jun, LIU Jian, LI Yun-gang   +3 more
doaj   +1 more source

Fluorine‐18‐Labeled Nucleotide Analogs Targeting Ecto‐5'‐Nucleotidase (CD73) for Positron Emission Tomography Imaging of Solid Tumors

Angewandte Chemie, EarlyView.
Fluorine‐18‐labeled CD73 inhibitor [18F]PSB‐19427 enables noninvasive PET mapping of CD73 overexpression in triple‐negative breast (TNBC) and pancreatic cancer. For [18F]PSB‐19427, specific binding in human tumor tissues, favorable biodistribution with prolonged blood retention, robust tumor uptake, and superiority to [18F]FDG in a TNBC model ...
Clemens Dobelmann, Constanze C. Schmies, Georg Wilhelm Rolshoven, Mirko Scortichini, Stefan Wagner, Andreas Isaak, Riham M. Idris, Jennifer Dabel, Lucie Grey, Karolina Losenkova, Susanne Moschütz, Haneen Al Hroub, Antje Keim, Sandra Höppner, Jouko Sandholm, Pia Boström, Maija Hollmén, Norbert Sträter, Sven Hermann, Gennady G. Yegutkin, Kenneth A. Jacobson, Sonja Schelhaas, Christa E. Müller, Anna Junker   +23 more
wiley   +2 more sources

Study on identification method of ¹⁴C-metsulfuron-methyl

浙江大学学报. 农业与生命科学版, 2001
The chemical purity of 14C-metsulfuron-methyl was determined by high performance liquid chromatography (HPLC), its radiochemical purity was measured by HPLC-LSC (Liquid Scintillation Counter) and TLC-isotope imaging analysis (TLC-IIA), respectively.
YE Qing-fu, SUN Jin-he
doaj   +1 more source

Positron Emission Tomography Imaging of Bacterial Infections With an Enterobactin Analog to Monitor Treatment Efficacy With a Catechol Antibiotic

Angewandte Chemie, EarlyView.
Synopsis. The [68Ga]GaIII‐TREN‐CAM radiochelate selectively accumulates in Gram‐negative sites of infection and noninvasively monitors treatment response a siderophore antibiotic. ABSTRACT Positron emission tomography (PET) is an emerging tool under clinical investigation for the detection of bacterial infections.
M. Andrey Joaqui‐Joaqui, Phuong Nguyen Tran, Axia Marlin, Fiona Armstrong‐Pavlik, Minhua Cao, Valérie C. Pierre, Eszter Boros   +6 more
wiley   +2 more sources