Results 21 to 30 of about 13,323 (173)

Automated synthesis and quality control of [68Ga]Ga-PentixaFor using the Gaia/Luna Elysia-Raytest module for CXCR4 PET imaging

EJNMMI Radiopharmacy and Chemistry, 2023
Background [68Ga]Ga-PentixaFor is a promising radiotracer for positron emission tomography imaging of several human tumors overexpressing the chemokine receptor-4 (CXCR4).
Thomas Daniel, Clara Balouzet Ravinet, Jérôme Clerc, Rui Batista, Yvan Mouraeff   +4 more
doaj   +1 more source

Determination of Radiochemical Purity of 99mTc-DTPA Using One-System Method of Paper Chromatography [PDF]

Journal of Pure and Applied Chemistry Research, 2019
The more efficient and effective quality control techniques for 99mTc-DTPA are needed because 99mTc has a short half-life of around 6.0 hours. We have succeeded in developing a one-system of TLC for radiochemical purity testing system that is faster and ...
Maskur Maskur, Enny Lestari, Amal Rezka Putra, Dede Kurniasih, Endang Sarmini, Yayan Tahyan, Adang Hardi Gunawan, Arni Aries   +7 more
doaj  

A Rapid Radiochemical Purity Testing Method for 99mTc-Tetrofosmin [PDF]

Journal of Nuclear Medicine Technology, 2010
The standard radiochemical purity (RCP) testing method for (99m)Tc-tetrofosmin as described in the package insert requires extensive time (20-30 min) and considerable skill to achieve accurate results. Additionally, the instant thin-layer chromatography strip impregnated with silica gel (2x20 cm) used in the standard method will not be commercially ...
Laura A, Eggert, Michael D, Dick, Douglas W, Mahoney, Joseph P, Olson, Gregory L, Werner, Joseph C, Hung   +5 more
openaire   +2 more sources

The optimization method for synthesis of technetium-99m-luteolin as radiotracer in the development of cancer drugs from flavonoid

Journal of Advanced Pharmaceutical Technology & Research, 2020
The aim of this study is to find the optimum conditions of labeling luteolin flavonoid compounds with technetium-99m (99mTc) to meet the purity requirements stated in the United States Pharmacopeia. This compound is expected to be a potential radiotracer
Danni Ramdhani, Maula Eka Sriyani, S Fairuz Nabila   +2 more
doaj   +1 more source

Development of an HPLC method for the radiochemical purity evaluation of [18F]fluoroestradiol

Brazilian Journal of Radiation Sciences, 2019
18F-Fluoroestradiol ([18F]FES), an estrogen analog, is a radiopharmaceutical used in Positron Emission Tomography (PET) that allows evaluating the tumor cell receptor profile and the best therapy strategy, the staging, the prognosis and the response to ...
Ana Carolina de Araujo Bispo, Leonardo Tafas Constantino Nascimento, Flávia Mesquita Costa, Juliana Batista da Silva, Marcelo Mamede   +4 more
doaj   +1 more source

Persistent Mono‐Oxo Bonding with Protactinium(V) Revealed in Highly Acidic Chloride Solutions

Angewandte Chemie, Volume 138, Issue 11, 9 March 2026.
Protactinium(V) defies expectations. Its elusive mono‐oxo bond was revealed through a combination of extended X‐ray absorption fine structure (EXAFS) and X‐ray absorption near‐edge structure (XANES) analyses, as well as quantum chemical calculations. This bond persists even in 12 M HCl.
Melody Maloubier, Tamara Shaaban, Florent Réal, Claire Le Naour, Hanna Oher, Titouan Aubert, Pier Lorenzo Solari, Bruno Siberchicot, Rémi Maurice, Valérie Vallet   +9 more
wiley   +2 more sources

Synthesis, Radiochemical Purity Control and Stability of Scandium-46-1,4,7-triazacyclononane-1,4,7-triacetic acid (⁴⁶Sc-NOTA)

Indonesian Journal of Chemistry, 2018
Radiotherapy is one of healing method of cancer using radionuclide elements. The radionuclide scandium-46 (46Sc) has a half-life of 83.8 days, beta emission 0.35 MeV and gamma emission 899 and 1120 keV is suitable for studying the chemical aspects ...
Duyeh Setiawan, Iwan Hastiawan, Asri Nurul Bashiroh   +2 more
doaj   +1 more source

A NeuroD1 AAV‐Based Gene Therapy for Functional Brain Repair in Alzheimer's Disease‐Like Non‐Human Primate Model

Advanced Science, EarlyView.
This study tests NeuroD1 AAV‐based gene therapy in a non‐human primate Alzheimer's disease model. The therapy prevents neuronal damage, inhibits hippocampal atrophy, and reduces neuroinflammation. It also repairs vascular and blood‐brain barrier damage, restores cerebrospinal fluid biomarkers, enhances hippocampal glucose metabolism, and improves ...
Zhouquan Jiang, Yongpeng Qin, Bin Luo, Fan Bai, Jiangyue Liu, Long Ma, Shu He, Rongjie Chen, Yuchen Wang, Shanggong Liu, Ying Sun, Yi Chen, Shuo Zhang, Jiaqi Liang, Feng Liao, Huiyi Wei, Junjie Wei, Lu Wang, Hao Xu, Zheng Wu, Gong Chen, Wenliang Lei   +21 more
wiley   +1 more source

Mapping CSC‐Mediated Ovarian Cancer Chemoresistance via CXCR4‐PET to Guide Precision Cisplatin Re‐Sensitization Therapy

Advanced Science, EarlyView.
CXCR4 functions as a potential cancer stem cell‐associated marker linked to chemoresistance in ovarian cancer, and an inhibitor of CXCR4, AMD3100, can enhance the cytotoxic response to cisplatin. Based on these findings, [68Ga]Ga‐Pentixafor positron emission tomography enables selective visualization of CXCR4‐high ovarian cancer, while AMD3100 combined
Lixia Feng, Simei Zhao, Zheng Wei, Wenwen Wang, Feiquan Ying, Lin Huang, Mengna Zhu, Mengqing Chen, Qiang Yang, Si Sun, Dawei Jiang, Lingling Gao, Jing Cai   +12 more
wiley   +1 more source

Tracking of [14C]Polystyrene Nanoplastics in Pregnant Mice

Advanced Science, EarlyView.
This study investigates [14C]polystyrene nanoplastic ([14C]PS) translocation in late‐stage pregnant mice after intranasal (0.5 mg of [14C]PS on GD12, GD14, and GD16, n = 6) and intravenous administration (1.5 mg of [14C]PS on GD16, n = 6). 14C‐radiolabel allows quantitative tracking of unmodified polystyrene nanoplastics.
Olga Khaybullina, Pallavi Sarkhel, Outi M. Keinänen   +2 more
wiley   +1 more source