Results 31 to 40 of about 13,323 (173)

Effect of High Activity Technetium-99m on the Stability of Tc-99m Tetrofosmin as Injectable radiopharmaceuticals [PDF]

open access: yesJournal of Pure and Applied Chemistry Research, 2018
Technetium-99m (Tc-99m) labeled tetrofosmin kit has been widely used in hospitals including in Indonesia. Usually, tetrofosmin kits and Tc-99m pertechnetate are supplied separately, but recently there has been a new trend where Tc-99m tetrofosmin is ...
Widyastuti Widjaksana   +3 more
doaj   +1 more source

A comparison of radiochemical purity testing of 99m Tc-Pentetate (DTPA) between paper and thin layer chromatographic techniques

open access: yesJournal of Associated Medical Sciences, 2016
Introduction: 99mTc-Pentetate or 99mTc-DTPA (99mTc-diethylenetriaminepentaacetic acid) is radiopharmaceutical material for renal function study in nuclear medicine.
Montree Tungjai   +2 more
doaj  

Stable BF2 Boracycles as Versatile Reagents for Selective Ortho C–H Functionalization

open access: yesAngewandte Chemie, Volume 138, Issue 8, 16 February 2026.
We report a robust, metal‐free and scalable synthesis of stable BF2 boracycles via directed ortho CH borylation, delivering isolable, shelf‐stable reagents without chromatographic purification. These BF2 boracycles exhibit unique and tunable reactivity, enabling highly selective ipso‐functionalization across a broad range of transformations.
Ganesh H. Shinde   +11 more
wiley   +2 more sources

An HPLC and UHPLC-HRMS approach to study PSMA-11 instability in aqueous solution

open access: yesEJNMMI Radiopharmacy and Chemistry, 2021
Background The stability of precursors and reagents is of utmost importance for developing a robust radiolabelling method that provides high and constant radiochemical yield and radiochemical purity.
Antonella Iudicello   +4 more
doaj   +1 more source

Radiochemical purity and particles number determinations of modified 99mTc-macroaggregated albumin [PDF]

open access: yesJournal of the Serbian Chemical Society, 2002
Anew procedure for the aggregation of human albumin and 99mTc-labelling of the prepared macroaggregated albumin are presented. Simple methods for quantifying of all the radiochemical impurities existing in 99mTc-MAA were tested.
Đokić Divna Đ.   +2 more
doaj   +3 more sources

Radiochemical Feasibility of Mixing of 99mTc-MAA and 90Y-Microspheres with Omnipaque Contrast

open access: yesMolecules, 2022
Yttrium-90 (90Y) microspheres are widely used for the treatment of liver-dominant malignant tumors. They are infused via catheter into the hepatic artery branches supplying the tumor under fluoroscopic guidance based on pre-therapy angiography and ...
Chang-Tong Yang   +6 more
doaj   +1 more source

OsFKBP20‐1b stabilizes OsUPF1 and OsUPF2 to promote the degradation of aberrant mRNAs during dehydration stress

open access: yesJournal of Integrative Plant Biology, EarlyView.
The rice protein OsFKBP20‐1b protects key RNA‐surveillance factors from breakdown, so they can better eliminate defective messages. This RNA quality‐control boost reduces errors and helps plants survive drought, revealing a link between RNA control and drought tolerance.
Haemyeong Jung   +5 more
wiley   +1 more source

Automated Scale-Down Development and Optimization of [68Ga]Ga-DOTA-EMP-100 for Non-Invasive PET Imaging and Targeted Radioligand Therapy of c-MET Overactivation in Cancer

open access: yesBiologics
Background/Objectives: Overactivation of the HGF/c-MET pathway is implicated in various cancers, making its inhibition a promising therapeutic strategy.
Silvia Migliari   +7 more
doaj   +1 more source

Influence of Peptide‐Based Chelator Sequences on HER2‐Targeting Radiopeptide

open access: yesJournal of Peptide Science, Volume 32, Issue 5, May 2026.
Peptide‐based chelator consisting of Cys‐Gly‐Gly‐Gly incorporated into HER2‐targeting rL‐A9 peptide for 99mTc‐labeling. [99mTc]Tc‐CGGG‐rL‐A9 exhibited high binding affinity and tumor uptake and retention. ABSTRACT In our pursuit of developing HER2‐targeting radiolabeled peptides for detection and therapy of HER2‐positive breast cancer, the previously ...
Sonal Gupta   +5 more
wiley   +1 more source

Physicochemical and Biological Analysis of 99mTc-Glutathione Radiopharmaceuticals

open access: yesAtom Indonesia, 2013
99mTc-glutation (99mTc-GSH) radiopharmaceutical is available in the GSH lyophilized-kit in which ready to use directly after adding 99mTc radionuclide.
M.E. Sriyani, N. Zainuddin
doaj  

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