Results 41 to 50 of about 13,323 (173)

Kinetic model of radiochemical oxygen depletion (ROD) in FLASH radiotherapy

Medical Physics, Volume 53, Issue 4, April 2026.
Abstract Background The role of oxygen in “Ultra‐High Dose Rate” (UHDR) radiotherapy is currently subject to active debate, due to its importance in the FLASH effect. Radiochemical oxygen depletion (ROD) is used to characterize the removal of oxygen by its interaction with the free radicals produced by the radiation.
Joao Seco, Hugo Freitas
wiley   +1 more source

radiochemical purity

, 2014
Citation: 'radiochemical purity' in the IUPAC Compendium of Chemical Terminology, 3rd ed.; International Union of Pure and Applied Chemistry; 2006. Online version 3.0.1, 2019. 10.1351/goldbook.R05096 • License: The IUPAC Gold Book is licensed under Creative Commons Attribution-ShareAlike CC BY-SA 4.0 International for individual terms.
openaire   +1 more source

Preparation, radiochemical purity control and stability of99mTc-mertiatide (Mag-3) [PDF]

Annals of Nuclear Medicine, 2005
Scintigraphic image analysis of 99mTc-mertiatide (Mag-3, mercaptoacetyltriglycine) clearance provides the determination of the blood flow, the tubular transit time and the excretion as well from both kidneys. Radiopharmaceutical routine recommends a radiochemical purity control before administration of the product to a patient.
van Hemert, F.J., van Lenthe, H., Schimmel, K.J.M., van Eck-Smit, B.L.F.   +3 more
openaire   +5 more sources

Targeting DNA‐LNPs to Endothelial Cells Improves Expression Magnitude, Duration, and Specificity

Advanced Science, Volume 13, Issue 14, 9 March 2026.
Attaching antibodies against endothelial cell surface proteins redirects the delivery and expression of DNA‐lipid nanoparticles to organs of interest. Our targeted nanoparticles enable organ‐selective DNA expression in the endothelium of the lungs, brain, or spleen, providing a therapeutic platform for dozens of endothelial‐centric diseases.
Nicolas Marzolini, Taylor V. Brysgel, Ryan J. Rahman, Eno‐Obong Essien, Saw Y. Nwe, Jichuan Wu, Aparajeeta Majumder, Manthan N. Patel, Sachchidanand Tiwari, Carolann L. Espy, Fengyi Dong, Sabrina A. Santos‐De León, Anit Shah, Vladimir V. Shuvaev, Elizabeth D. Hood, Liam S. Chase, Drew Weissman, Jeremy B. Katzen, David B. Frank, Mariko L. Bennett, Oscar A. Marcos‐Contreras, Jacob W. Myerson, Vladimir R. Muzykantov, Sahily Reyes‐Esteves, Jacob S. Brenner   +24 more
wiley   +1 more source

Synthesis of an Al18F radiofluorinated GLU-UREA-LYS(AHX)-HBED-CC PSMA ligand in an automated synthesis platform

EJNMMI Radiopharmacy and Chemistry, 2018
Background Overexpression of prostatic membrane antigen (PSMA) is associated with the progression and prognosis of prostate cancer. There are numerous studies using this peptide with the 68Ga radionuclide.
Javier Giglio, Maia Zeni, Eduardo Savio, Henry Engler   +3 more
doaj   +1 more source

Synthesis, Radiochemical Characterization, and Biodistribution of a 188Re Analogue of [131I]mIBG in a Neuroblastoma Xenograft Model

Journal of Labelled Compounds and Radiopharmaceuticals, Volume 69, Issue 3, March 2026.
A 188Re analogue of [131I]mIBG was synthesized in moderate yields using 188Re‐4 + 1 chemistry. In vitro studies using SK‐N‐SH neuroblastoma cell lines demonstrated that the compound exhibited affinity for norepinephrine transporters expressed on these cancer cells.
Navin Sakhare, Dheeraj Kumar, Soumen Das, Arpit Mitra, Shubhangi Mirapurkar, G. Rani, M. Sheela, Viju Chirayil, Bhabani Mohanty, Anupam Mathur, Madhava B. Mallia, Pradip Chaudhari   +11 more
wiley   +1 more source

Establishment of Ion Chromatography Method for Identification and Determination of the Radiochemical Purity of [11C]Choline Injection

Journal of Isotopes
[11C]choline is a normal tracer using for PET/CT，identification of [11C]choline and analysis its radiochemical purity are important to guarantee the validity and safety of tracer.
Guojin ZHANG, Shanzhen HE
doaj   +1 more source

Technetium-99m-labeled genistein as a potential radical scavenging agent

Journal of Advanced Pharmaceutical Technology & Research, 2019
The purpose of this study was to determine the optimum conditions for labeling genistein compounds with technetium-99m (99mTc) radionuclides and the percentage of purity obtained in accordance with the requirements of the United State Pharmacopeia.
Danni Ramdhani, Maula Eka Sriyani, Flamboyan Ayu   +2 more
doaj   +1 more source

Low‐dose testosterone administration and oestrogen synthase availability in the female brain: A pilot study

Journal of Neuroendocrinology, Volume 38, Issue 3, March 2026.
Abstract Testosterone and oestrogens play significant roles in female physiology, extending beyond reproductive functions to influence brain health, mood regulation, and behaviour. Testosterone low‐dose therapy is increasingly considered for alleviating sexual dysfunction symptoms in postmenopausal women, and has been recently investigated as therapy ...
Manon Dubol, My Jonasson, Kayo Takahashi, Johan Wikström, Yasuyoshi Watanabe, Gunnar Antoni, Mark Lubberink, Anat Biegon, Inger Sundström‐Poromaa, Erika Comasco   +9 more
wiley   +1 more source

Establishment of Thin Layer Chromatographic Method for Determination of Radiochemical Purity of Technetium[99mTc] Methylenediphosphonate Injection

Journal of Isotopes, 2023
To establish a reliable method for measuring the radiochemical purity of technetium[99mTc] methylenediphosphonate injection, analysis conditions such as stationary phase and developing solvent were studied.
WANG Yong, LIANG Su, CUI Xiaoyan, JIANG Hua, ZHANG Yun, YANG Liu
doaj