Results 111 to 120 of about 15,914 (251)

The effect of temperature on the bystander effect as examined in human prostate carcinoma cells with alpha particle irradiation [PDF]

, 2006
Thesis (S.B.)--Massachusetts Institute of Technology, Dept. of Nuclear Science and Engineering, 2006."June 2006."Includes bibliographical references (p. 30-32).The bystander effect is seen when irradiated cells release a factor that can produce damage or
Sheppard, Sarah (Sarah Elizabeth)
core  

Radioimmunotherapy: a brief overview

Biomedical Imaging and Intervention Journal, 2006
With the advent of biotechnological advances and knowledge of molecular and cellular biology, radioimmunotherapy (RIT) has become a highly promising oncologic therapeutic modality with established clinically efficacy, particularly in non-Hodgkin's lymphomas.
openaire   +2 more sources

¹⁷⁷Lu Anti-Angiogenic Radioimmunotherapy Targeting ATP Synthase in Gastric Cancer Model

Antibodies
This study investigated a novel radioimmunotherapy strategy for targeting tumor angiogenesis. We developed a radiopharmaceutical complex by labeling an anti-adenosine triphosphate synthase (ATPS) monoclonal antibody (mAb) with the radioisotope 177Lu ...
Bok-Nam Park, Young-Sil An, Su-Min Kim, Su-Jin Lee, Yong-Jin Park, Joon-Kee Yoon   +5 more
doaj   +1 more source

Radioimmunotherapy in Non-Hodgkin’s Lymphoma: Retrospective Adverse Event Profiling of Zevalin and Bexxar

Pharmaceuticals, 2019
The development of monoclonal antibodies has dramatically changed the outcome of patients with non-Hodgkin’s lymphoma (NHL), the most common hematological malignancy.
Christos Sachpekidis, David B. Jackson, Theodoros G. Soldatos   +2 more
doaj   +1 more source

Biological intratumoral therapy for the high-grade glioma part II: vector- and cell-based therapies and radioimmunotherapy

CNS Oncology, 2019
Management of high-grade gliomas (HGGs) remains a complex challenge with an overall poor prognosis despite aggressive multimodal treatment. New translational research has focused on maximizing tumor cell eradication through improved tumor cell targeting ...
Joshua Loya, Charlie Zhang, Emily Cox, Achal S Achrol, Santosh Kesari   +4 more
doaj   +1 more source

Targeted alpha therapy in vivo: direct evidence for single cancer cell kill using 149Tb-rituximab [PDF]

, 2018
This study demonstrates high-efficiency sterilisation of single cancer cells in a SCID mouse model of leukaemia using rituximab, a monoclonal antibody that targets CD20, labelled with terbium-149, an alpha-emitting radionuclide.
Beyer, G.-J, Buchegger, F., Hartley, O., Künzi, G., Miederer, M., Senekowitsch-Schmidtke, R., Soloviev, D., Vranješ-Đurić, S., Čomor, J.   +8 more
core  

LBA3 Compartmental radioimmunotherapy (cRIT) 131I-OMBURTAMAB in patients with neuroblastoma (NB) central nervous system (CNS) and/or leptomeningeal (LM) metastases: Updated results from pivotal Trial 101

, 2022
Ellen M. Basu, J. Mora, K. Streby, M. Bear, H. Sano, A. Marachelian, D. Harrison, K. Nysom, N. Pandit-Taskar, P. Zanzonico, S. Fabricius, M. During, J.R. Nielsen, K. Kramer   +13 more
openalex   +1 more source

Radioimmunotherapy Confers Long-Term Survival to Lymphoma Patients with Acceptable Toxicity: Registry Analysis by the International Radioimmunotherapy Network [PDF]

, 2011
Karin Hohloch, Angelika Bischof Delaloye, Christiane Windemuth‐Kieselbach, José Gómez‐Codina, Werner Linkesch, Wojciech Jurczak, Roberto Cacchione, Cheolwon Suh, Pier Luigi Zinzani, Lorenz Trümper   +9 more
openalex   +1 more source

Risk of histological transformation and therapy‐related myelodysplasia/acute myeloid leukaemia in patients receiving radioimmunotherapy for follicular lymphoma [PDF]

, 2017
Narendranath Epperla, Anthony Pham, Brian L. Burnette, Gregory A. Wiseman, Thomas M. Habermann, William R. Macon, Stephen M. Ansell, David J. Inwards, Ivana N. Micallef, Patrick B. Johnston, Svetomir N. Markovic, Luis F. Porrata, Joseph P. Colgan, Kay M. Ristow, Grzegorz S. Nowakowski, Thomas E. Witzig   +15 more
openalex   +1 more source

Targeting Cancer Stem Cells with Radioimmunotherapy: The Case of the Ovarian Cancer Stemness-Associated Biomarker L1CAM

International Journal of Translational Medicine
Cancer stem cells (CSCs) are a dynamic population of tumor cells characterized by long-term self-renewal, high tumorigenicity, resistance to conventional therapies such as radio- and chemotherapy, and capacity to recapitulate the tumor heterogeneity ...
Tihomir Zh. Todorov, Roger Schibli, Martin Béhé, Jürgen Grünberg   +3 more
doaj   +1 more source