Results 161 to 170 of about 88,244 (379)

In vitro/in vivo assessment of novel 99mTc-bombesin conjugates in human cancer tissue [abstract] [PDF]

open access: yes, 2007
only availableReceptor-specific, radiolabeled peptides are becoming increasingly popular as targeting vectors for the development of new diagnostic radiopharmaceuticals.
Heinzke, Laura   +7 more
core  

Functional Characterization of the Cat and Dog Wild‐Type and Mutant MDR1 Carrier Proteins and Frequency of the MDR1 Gene Mutation in 800 Cats From Germany

open access: yesJournal of Veterinary Pharmacology and Therapeutics, EarlyView.
ABSTRACT The ATP‐binding cassette transporter MDR1 P‐glycoprotein (syn. ABCB1) is an efflux carrier at the cell membrane that regulates drug absorption, distribution, and elimination. At the blood–brain barrier, MDR1 restricts brain entry of potentially neurotoxic drugs, such as ivermectin. In dogs and cats, MDR1 (syn.
Lisa Siegl   +6 more
wiley   +1 more source

Development of a Radiolabeled Folate-Mediated Drug Delivery System for Effective Delivery of Docetaxel [PDF]

open access: gold, 2023
Oğuz Çetin   +8 more
openalex   +1 more source

The FsrA‐Mediated Iron‐Sparing Response Regulates the Biosynthesis of the Epipeptide EPE in Bacillus subtilis

open access: yesMolecular Microbiology, EarlyView.
Under iron‐limited conditions, FsrA base‐pairs with the intergenic region between epeX and epeE, enhancing epeE translation and triggering EPE production. Toxin‐mediated cell lysis releases nutrients, including iron, which can be taken up by surviving cells.
Sarah Miercke   +3 more
wiley   +1 more source

Jasmonate Modulates Strawberry Susceptibility to Anthracnose by Activating SnRK2.1 to Regulate the WRKY50‐JAZ5 Module

open access: yesPlant Biotechnology Journal, EarlyView.
ABSTRACT Colletotrichum spp., hemibiotrophic fungal pathogens, threaten global strawberry production. Jasmonate (JA) regulates plant‐Colletotrichum interactions, but its mechanisms remain unclear. Here we demonstrate that both exogenous methyl jasmonate (MeJA) treatment and elevated endogenous MeJA levels increase strawberry susceptibility to ...
Chuang Liu   +10 more
wiley   +1 more source

A new precursor for the preparation of 6-[18F]Fluoro-l-m-tyrosine ([18F]FMT): efficient synthesis and comparison of radiolabeling

open access: green, 2004
Henry F. VanBrocklin   +6 more
openalex   +2 more sources

Plastid Engineering for Photosynthesis‐Driven Synthesis of Hyaluronic Acid in Tobacco

open access: yesPlant Biotechnology Journal, EarlyView.
ABSTRACT Hyaluronic acid (HA) is a glycosaminoglycan composed of alternating units of N‐acetylglucosamine and glucuronic acid. High moisture retention, viscoelasticity and biocompatibility are unique features that make HA polymers attractive compounds for medical applications and aesthetic purposes.
Amanda Lopes   +10 more
wiley   +1 more source

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