Results 11 to 20 of about 88,244 (379)
Radiolabeling human peripheral blood stem cells for positron emission tomography (PET) imaging in young rhesus monkeys. [PDF]
PLoS ONE, 2013 These studies focused on a new radiolabeling technique with copper ((64)Cu) and zirconium ((89)Zr) for positron emission tomography (PET) imaging using a CD45 antibody.
Alice F Tarantal +3 more
doaj +5 more sources
Metabolic radiolabeling and in vivo PET imaging of cytotoxic T lymphocytes to guide combination adoptive cell transfer cancer therapy [PDF]
Journal of Nanobiotechnology, 2021 Background Adoptive T cell transfer-based immunotherapy yields unsatisfactory results in the treatment of solid tumors, partially owing to limited tumor infiltration and the immunosuppressive microenvironment in solid tumors.
D. Lu +8 more
semanticscholar +2 more sources
Radiolabeling, Quality Control and In Vivo Imaging of Multimodal Targeted Nanomedicines
Pharmaceutics, 2022 Following our previous study on the development of EGFR-targeted nanomedicine (NM-scFv) for the active delivery of siRNA in EGFR-positive cancers, this study focuses on the development and the quality control of a radiolabeling method to track it in in ...
Phuoc-Vinh Nguyen +7 more
doaj +1 more source
The role of radiolabeling in BNCT tracers for enhanced dosimetry and treatment planning
Theranostics, 2023 Positron emission tomography (PET) and single photon emission computed tomography (SPECT) are potent technologies for non-invasive imaging of pharmacological and biochemical processes in both preclinical and advanced clinical research settings.
Sajid Mushtaq +4 more
semanticscholar +1 more source
PET Imaging of Small Extracellular Vesicles via [89Zr]Zr(oxinate)4 Direct Radiolabeling
Bioconjugate chemistry, 2022 Exosomes or small extracellular vesicles (sEVs) are increasingly gaining attention for their potential as drug delivery systems and biomarkers of disease.
Azalea A Khan +11 more
semanticscholar +1 more source
Anti-CD20 Immunoglobulin G Radiolabeling with a 99mTc-Tricarbonyl Core: In Vitro and In Vivo Evaluations. [PDF]
PLoS ONE, 2015 In recent years, the diagnostic and therapeutic uses of radioisotopes have shown significant progress. Immunoglobulin (Ig) appears to be a promising tracer, particularly due to its ability to target selected antigens.
Hélène Carpenet +3 more
doaj +1 more source
Bioconjugate chemistry, 2021 Inert and stable radiolabeling of monoclonal antibodies (mAb), antibody fragments, or antibody mimetics with radiometals is a prerequisite for immuno-PET.
Marion Chomet +2 more
semanticscholar +1 more source
Cancers, 2021 Simple Summary In nuclear medicine, therapeutic methods are used increasingly, in which tumors are destroyed by ionizing radiation that cannot or can only be treated insufficiently by other methods like surgery or chemotherapy.
Falco Reissig +9 more
semanticscholar +1 more source
Pharmaceutics, 2022 Quercetin (QRC) is a bioflavonoid with anti-inflammatory, antioxidant, and anticancer activities, yet QRC poor bioavailability has hampered its clinical implementation. The aim of the current work was to harness novasomes (NOVs), free fatty acid enriched
Heba M. Aboud +5 more
doaj +1 more source
Cell radiolabeling with acoustophoresis cell washing
Scientific Reports, 2022 Labeling immune cells with zirconium-89 (89Zr)-oxine has become a viable method to track cells in vivo by PET in various pre-clinical animal models and in clinical applications.
S. Adler +4 more
semanticscholar +1 more source