Results 31 to 40 of about 32,685 (264)
Hepatology, EarlyView., 2022 Increased liver content of DHA‐derived small lipid autacoids (i.e resolvin D1 and maresin 1) associates with enhanced mitochondrial oxidative phosphorylation, fatty acid β‐oxidation and bioenergetic metabolic flux. These features provide hepatic protection from steatotic, pro‐inflammatory and fibrogenic insults.
Cristina López‐Vicario +12 more
wiley +1 more source
Hepatology, EarlyView., 2022 Adaptive mitochondrial mechanisms allow mitochondrial resilience and prevent the worsening of fibrosis, while deregulation of these mechanisms promotes the progression from no/minimal‐mild (F0‐F2) fibrosis to advanced fibrosis and cirrhosis (F3‐F4). Abstract Background and Aims Hepatitis B virus (HBV) infection causes oxidative stress (OS) and alters ...
Dimitri Loureiro +17 more
wiley +1 more source
Pharmaceutics, 2020 Actinium-225 (225Ac) is receiving increased attention for its application in targeted radionuclide therapy, due to the short range of its emitted alpha particles in conjunction with their high linear energy transfer, which lead to the eradication of ...
Evangelia-Alexandra Salvanou +11 more
doaj +1 more source
Preparation and biological studies of 68Ga-DOTA-alendronate [PDF]
Asia Oceania Journal of Nuclear Medicine and Biology, 2016 Objective(s): In line with previous research on the development of conjugated bisphosphonate ligands as new bone-avid agents, in this study, DOTA conjugated alendronate (DOTA-ALN) was synthesized and evaluated after labeling with gallium-68 (68Ga ...
Ashraf Fakhari +4 more
doaj +1 more source
Molecules, 2020 Concern about environmental exposure to hazardous substances has grown over the past several decades, because these substances have adverse effects on human health.
Jae Young Lee +5 more
doaj +1 more source
, 2022 His-tagged scFv fragments of monoclonal antibodies have better pharmacokinetic properties than whole antibodies. Radiolabeled scFvs are considered for targeted imaging and treatment.
Kordi, Mohammadsaeed +8 more
core +1 more source
From Host to Phage Metabolism: Hot Tales of Phage T4’s Takeover of E. coli
Viruses, 2018 The mechanisms by which bacteriophage T4 converts the metabolism of its E. coli host to one dedicated to progeny phage production was the subject of decades of intense research in many labs from the 1950s through the 1980s.
Elizabeth Kutter +5 more
doaj +1 more source
Insights into Elution of Anion Exchange Cartridges: Opening the Path towards Aliphatic 18F-Radiolabeling of Base-Sensitive Tracers [PDF]
, 2021 Aliphatic nucleophilic substitution (SN2) with [18F]fluoride is the most widely applied method to prepare 18F-labeled positron emission tomography (PET) tracers.
Tomas G, Ohlsson +8 more
core +1 more source
The influence of generator eluate in radiolabeling PSMA-11 kit with 68Ga
Brazilian Journal of Radiation Sciences, 2021 Gaining prominence in clinical practice, the 68Ga, positron emitter radionuclide easily obtained by 68Ge/68Ga generator elution, has shown potential and excellent quality on radiolabeling of peptide for use in positron emission tomography (PET), in ...
Bianca Franchesqueti Vivaldini +1 more
doaj +1 more source
Radiolabeling of Theranostic Nanosystems [PDF]
, 2021 In the recent years, progress in nanotechnology has significantly contributed to the development of novel pharmaceutical formulations to overcome the drawbacks of conventional treatments and improve the therapeutic outcome in many diseases, especially cancer.
Das, Sudeep +3 more
openaire +5 more sources