Anti-CD20 Immunoglobulin G Radiolabeling with a 99mTc-Tricarbonyl Core: In Vitro and In Vivo Evaluations. [PDF]
PLoS ONE, 2015 In recent years, the diagnostic and therapeutic uses of radioisotopes have shown significant progress. Immunoglobulin (Ig) appears to be a promising tracer, particularly due to its ability to target selected antigens.
Hélène Carpenet +3 more
doaj +2 more sources
Radiolabeling human peripheral blood stem cells for positron emission tomography (PET) imaging in young rhesus monkeys. [PDF]
PLoS ONE, 2013 These studies focused on a new radiolabeling technique with copper ((64)Cu) and zirconium ((89)Zr) for positron emission tomography (PET) imaging using a CD45 antibody.
Alice F Tarantal +3 more
doaj +3 more sources
Radiolabeling, Quality Control and In Vivo Imaging of Multimodal Targeted Nanomedicines
Pharmaceutics, 2022 Following our previous study on the development of EGFR-targeted nanomedicine (NM-scFv) for the active delivery of siRNA in EGFR-positive cancers, this study focuses on the development and the quality control of a radiolabeling method to track it in in ...
Phuoc-Vinh Nguyen +7 more
doaj +2 more sources
Radiolabeling of Nanomaterials: Advantages and Challenges
Frontiers in Toxicology, 2021 Quantifying the distribution of nanomaterials in complex samples is of great significance to the toxicological research of nanomaterials as well as their clinical applications.
Chun-Lei Jiao, Xiao He, Yayun Ding
exaly +3 more sources
Chemically Modified Extracellular Vesicles and Applications in Radiolabeling and Drug Delivery
Pharmaceutics, 2022 Extracellular vesicles (EVs) have been exploited as bio-inspired drug delivery systems (DDS) in the biomedical field. EVs have more advantages than synthetic nanoparticles: they are naturally equipped to cross extra- and intra-cellular barriers ...
Nicola S Orefice +2 more
exaly +3 more sources
Scaling-down antibody radiolabeling reactions with zirconium-89 [PDF]
, 2016 The most widely cited procedures for radiolabeling antibodies with zirconium-89 for immuno-PET require multi-milligram amounts of antibody which can be cost-prohibitive, particularly during the research and development process.
Paisey, Stephen J. +15 more
core +6 more sources
Radiolabeled Bombesin Analogs [PDF]
Cancers, 2021 The gastrin-releasing peptide receptor (GRPR) is expressed in high numbers in a variety of human tumors, including the frequently occurring prostate and breast cancers, and therefore provides the rationale for directing diagnostic or therapeutic radionuclides on cancer lesions after administration of anti-GRPR peptide analogs.
Rosalba Mansi +5 more
openaire +3 more sources
Radiolabeling of gamma-irradiated rosmarinic acid by 67Gallium [PDF]
مجله علوم و فنون هستهای, 2023 Rosemary plant extract as a natural anti-oxidant is 4 times stronger than synthetic anti-oxidant like BHT and BHA. For this reason, it has been under attention not only for its anti-oxidant properties rather for its anti-inflammatory, anti-tumor, anti ...
N. Damavandi Kamali +2 more
doaj +1 more source
Radiolabeled PSMA Inhibitors [PDF]
Cancers, 2021 PSMA has shown to be a promising target for diagnosis and therapy (theranostics) of prostate cancer. We have reviewed developments in the field of radio- and fluorescence-guided surgery and targeted photodynamic therapy as well as multitargeting PSMA inhibitors also addressing albumin, GRPr and integrin αvβ3.
Oliver C. Neels +3 more
openaire +4 more sources
Preparation, Biodistribution of 99mTc-Azacytidine Complex as a Potential Agent for Radiotherapy [PDF]
Journal of Advanced Pharmacy Research, 2018 Objectives: This study aimed at exploring the possibility of radiolabeling 5-Azacytidine with technetium-99m (99mTc) as a surrogate for Rhenium- 186/188 in order to explore the possibility of using the radiolabeled complex as a targeted radiotherapeutic ...
Wafaa Zaghary +3 more
doaj +1 more source