Results 21 to 30 of about 33,330 (276)

Tailoring of Selenium-Plated Novasomes for Fine-Tuning Pharmacokinetic and Tumor Uptake of Quercetin: In Vitro Optimization and In Vivo Radiobiodistribution Assessment in Ehrlich Tumor-Bearing Mice

Pharmaceutics, 2022
Quercetin (QRC) is a bioflavonoid with anti-inflammatory, antioxidant, and anticancer activities, yet QRC poor bioavailability has hampered its clinical implementation. The aim of the current work was to harness novasomes (NOVs), free fatty acid enriched
Heba M. Aboud, Amal K. Hussein, Abdallah Z. Zayan, Tarek Saad Makram, Mona O. Sarhan, Dina M. El-Sharawy   +5 more
doaj   +1 more source

Ultra-Radiostable Covalent Conformationally Interlocked Networks Enabling a Universal Radiometal-Labeling Platform for Cancer Radioembolization. [PDF]

Adv Sci (Weinh)
Conjugated poly(imide dioxime)‐based microspheres establish a radiometal coordination‐driven conformational interlocked network with ultra‐high radiostability. This platform enables low‐temperature, multi‐radionuclide labeling for SPECT/PET/MRI imaging and radionuclide therapy. Mechanistic insights from EXAFS and DFT reveal enhanced stability, while in
Xu X, Zhao Z, Wang Y, Liu Z, Liu Z, Li X, Mao Z, Xu L, Lin G, Liu G, Ma H.   +10 more
europepmc   +2 more sources

Fate of Sulfonamides and Tetracyclines in Meat during Pan Cooking: Focus on the Thermodegradation of Sulfamethoxazole

Molecules, 2022
Although antimicrobials are generally found in trace amounts in meat, the human health risk they bear cannot be ignored. With the ultimate aim of making a better assessment of consumer exposure, this study explored the effects of pan cooking on ...
Christelle Planche, Sylvie Chevolleau, Maria-Hélèna Noguer-Meireles, Isabelle Jouanin, Sophie Mompelat, Jérémy Ratel, Eric Verdon, Erwan Engel, Laurent Debrauwer   +8 more
doaj   +1 more source

Scandium Radioisotopes—Toward New Targets and Imaging Modalities

Molecules, 2023
The concept of theranostics uses radioisotopes of the same or chemically similar elements to label biological ligands in a way that allows the use of diagnostic and therapeutic radiation for a combined diagnosis and treatment regimen.
Krzysztof Kilian, Krystyna Pyrzyńska
doaj   +1 more source

Synthesis and radiolabeling of PSMA-targeted derivatives containing GYK/MVK cleavable linkers [PDF]

, 2023
This file contains all identification, characterisation and radiolabeling data of the compounds described in the main ...
Sophie van den Berg (6884420), van den Berg, Sophie, Yann Seimbille (3763366), Erik de Blois (3763228), de Jong, Marion, Murce, Erika, de Blois, Erik, Seimbille, Yann; id_orcid, Erika Murce (14668466), Marion de Jong (10321291), Sophie van den Berg, Seimbille, Yann, Yann Seimbille, Erika Murce, Erik de Blois, Marion de Jong   +15 more
core   +1 more source

Advances in Development of Radiometal Labeled Amino Acid-Based Compounds for Cancer Imaging and Diagnostics

Pharmaceuticals, 2021
Radiolabeled biomolecules targeted at tumor-specific enzymes, receptors, and transporters in cancer cells represent an intensively investigated and promising class of molecular tools for the cancer diagnosis and therapy.
Mária Bodnár Mikulová, Peter Mikuš
doaj   +1 more source

Preliminary Evaluation of Iron Oxide Nanoparticles Radiolabeled with ⁶⁸Ga and ¹⁷⁷Lu as Potential Theranostic Agents

Nanomaterials, 2022
Theranostic radioisotope pairs such as Gallium-68 (68Ga) for Positron Emission Tomography (PET) and Lutetium-177 (177Lu) for radioisotopic therapy, in conjunction with nanoparticles (NPs), are an emerging field in the treatment of cancer.
Evangelia-Alexandra Salvanou, Argiris Kolokithas-Ntoukas, Christos Liolios, Stavros Xanthopoulos, Maria Paravatou-Petsotas, Charalampos Tsoukalas, Konstantinos Avgoustakis, Penelope Bouziotis   +7 more
doaj   +1 more source

Iodine-125 radiolabeling of silver nanoparticles for in vivo SPECT imaging [PDF]

, 2010
Adrian Chrastina, Jan E SchnitzerProteogenomics Research Institute for Systems Medicine, San Diego, CA, USAAbstract: Silver nanoparticles are increasingly finding applications in medicine; however, little is known about their in vivo tissue distribution.
Adrian Chrastina, null Schnitzer, Jan E Schnitzer   +2 more
core   +1 more source

Radiolabeling of functional oligonucleotides for molecular imaging

Frontiers in Bioengineering and Biotechnology, 2022
Molecular imaging has greatly advanced basic biology and translational medicine through visualization and quantification of molecular events in a cellular context and living organisms.
Dunfang Liu, Dunfang Liu, Qian Xia, Qian Xia, Ding Ding, Weihong Tan, Weihong Tan, Weihong Tan   +7 more
doaj   +1 more source

Synthesis and Evaluation of Fluorine-18-Labeled L-Rhamnose Derivatives

Molecules, 2023
The use of radiolabeled glucose for PET imaging resulted in the most commonly used tracer in the clinic, 2-deoxy-2-[18F]fluoroglucose (FDG). More recently, other radiolabeled sugars have been reported for various applications, including imaging tumors ...
Xiang Zhang, Falguni Basuli, Zhen-Dan Shi, Swati Shah, Jianfeng Shi, Amelia Mitchell, Jianhao Lai, Zeping Wang, Dima A. Hammoud, Rolf E. Swenson   +9 more
doaj   +1 more source