Results 21 to 30 of about 88,244 (379)
Frontiers in Medicine, 2021 Targeted radionuclide therapy (TRNT) is a promising approach for cancer therapy. Terbium has four medically interesting isotopes (149Tb, 152Tb, 155Tb and 161Tb) which span the entire radiopharmaceutical space (TRNT, PET and SPECT imaging). Since the same
Irwin Cassells +8 more
semanticscholar +1 more source
Nanobody-Based Theranostic Agents for HER2-Positive Breast Cancer: Radiolabeling Strategies
International Journal of Molecular Sciences, 2021 The overexpression of human epidermal growth factor 2 (HER2) in breast cancer (BC) has been associated with a more aggressive tumor subtype, poorer prognosis and shorter overall survival.
I. Hrynchak +4 more
semanticscholar +1 more source
Molecules, 2022 Although antimicrobials are generally found in trace amounts in meat, the human health risk they bear cannot be ignored. With the ultimate aim of making a better assessment of consumer exposure, this study explored the effects of pan cooking on ...
Christelle Planche +8 more
doaj +1 more source
Blood-brain barrier transport kinetics of NOTA-modified proteins : the somatropin case [PDF]
, 2020 BACKGROUND: Chemical modifications such as PEG, polyamine and radiolabeling on proteins can alter their pharmacokinetic behaviour and their blood-brain barrier (BBB) transport characteristics. NOTA, i.e. 1,4,7-triazacyclononane-1,4,7-triacetic acid, is a
Bracke, Nathalie +7 more
core +1 more source
Scandium Radioisotopes—Toward New Targets and Imaging Modalities
Molecules, 2023 The concept of theranostics uses radioisotopes of the same or chemically similar elements to label biological ligands in a way that allows the use of diagnostic and therapeutic radiation for a combined diagnosis and treatment regimen.
Krzysztof Kilian, Krystyna Pyrzyńska
doaj +1 more source
Biomolecules, 2021 By using solid targets in medical cyclotrons, it is possible to produce large amounts of 68GaCl3. Purification of Ga3+ from metal ion impurities is a critical step, as these metals compete with Ga3+ in the complexation with different chelators, which ...
E. Jussing +7 more
semanticscholar +1 more source
Pharmaceuticals, 2021 Radiolabeled biomolecules targeted at tumor-specific enzymes, receptors, and transporters in cancer cells represent an intensively investigated and promising class of molecular tools for the cancer diagnosis and therapy.
Mária Bodnár Mikulová, Peter Mikuš
doaj +1 more source
Advanced Healthcare Materials, 2021 Gold nanocages (AuNCs) have emerged as a novel class of multifunctional nanomaterials with an array of applications in nanomedicine, including drug delivery, controlled release, as well as disease diagnosis and treatment.
Jichuan Qiu, Yongjian Liu, Younan Xia
semanticscholar +1 more source
Pharmaceuticals, 2021 Prostate-specific membrane antigen (PSMA) is a glycoprotein present in the prostate, that is overexpressed in prostate cancer (PCa). Recently, PSMA-directed radiopharmaceuticals have been developed, allowing the pinpointing of tumors with the Positron ...
L. L. Fuscaldi +8 more
semanticscholar +1 more source