Results 71 to 80 of about 87,481 (331)

99mTc-Labeled Iron Oxide Nanoparticles as Dual-Modality Contrast Agent: A Preliminary Study from Synthesis to Magnetic Resonance and Gamma-Camera Imaging in Mice Models

open access: yesNanomaterials, 2022
The combination of two imaging modalities in a single agent has received increasing attention during the last few years, since its synergistic action guarantees both accurate and timely diagnosis.
Maria-Argyro Karageorgou   +6 more
doaj   +1 more source

Electrical pulse stimulation reflecting the episodic nature of real‐life exercise modulates metabolic and secretory profile of primary human myotubes

open access: yesFEBS Open Bio, EarlyView.
Here, we introduced an intermittent electrical stimulation protocol mimicking the episodic nature of real‐life exercise in vitro by alternating low‐ and high‐frequency stimulation. In comparison with widely used continuous stimulation, it enhanced the rate of glucose and fatty acid oxidation, but not the myokine release.
Klára Gabrišová   +11 more
wiley   +1 more source

The Different Strategies for the Radiolabeling of [211At]-Astatinated Radiopharmaceuticals

open access: yesPharmaceutics
Astatine-211 (211At) has emerged as a promising radionuclide for targeted alpha therapy of cancer by virtue of its favorable nuclear properties. However, the limited in vivo stability of 211At-labeled radiopharmaceuticals remains a major challenge.
Jie Gao   +6 more
doaj   +1 more source

Radiolabeled Liposomes for Nuclear Imaging Probes

open access: yesMolecules, 2023
Quantitative nuclear imaging techniques are in high demand for various disease diagnostics and cancer theranostics. The non-invasive imaging modality requires radiotracing through the radioactive decay emission of the radionuclide.
Ho Ying Low   +5 more
doaj   +1 more source

Aptamer-based therapeutics and their potential in radiopharmaceutical design [PDF]

open access: yes, 2007
Aptamers, short, single stranded oligonucleotide entities, have been developed in the past 15 years against a plethora of targets and for a variety of applications.
Ferreira, Catia S. M.   +1 more
core   +3 more sources

Metal Nanoclusters for Cancer Imaging and Treatment

open access: yesAdvanced Functional Materials, EarlyView.
This review aims to provide a comprehensive summary and discussion of the core–shell design capabilities of metal nanoclusters (NCs) at the atomic level for cancer imaging and treatment. It offers essential insights into the design principles of metal NCs while also encouraging the exploration of other nanomaterials and their potential theranostic ...
Haiguang Zhu   +5 more
wiley   +1 more source

Radiolabeled Iron Oxide Nanoparticles as Dual Modality Contrast Agents in SPECT/MRI and PET/MRI

open access: yesNanomaterials, 2023
During the last decades, the utilization of imaging modalities such as single photon emission computed tomography (SPECT), positron emission tomography (PET), and magnetic resonance imaging (MRI) in every day clinical practice has enabled clinicians to ...
Maria-Argyro Karageorgou   +3 more
doaj   +1 more source

Removal of Steroid Hormone Micropollutants by an Electrochemical Carbon Nanotube Membrane Flow‐Through Reactor: Role of Concentration and Degradation Mechanisms

open access: yesAdvanced Functional Materials, EarlyView.
A flow‐through electrochemical membrane reactor equipped with a carbon nanotube membrane eliminates the mass transfer limitation, achieving removals >97.5% for steroid hormone (SH) micropollutants through electrochemical adsorption and degradation, over a broad initial concentration varying from 50 to 106 ng L−1.
Siqi Liu   +2 more
wiley   +1 more source

Biodistribution of a Radiolabeled Antibody in Mice as an Approach to Evaluating Antibody Pharmacokinetics

open access: yesPharmaceutics, 2018
(1) Background: Monoclonal antibodies are used in the treatment of multiple conditions including cancer, autoimmune disorders, and infectious diseases.
Kevin J. H. Allen   +4 more
doaj   +1 more source

Synthesis of [11C]CX-6258 as a new PET tracer for imaging of Pim kinases in cancer [PDF]

open access: yes, 2015
The reference standard CX-6258 {(E)-5-chloro-3-((5-(3-(4-methyl-1,4-diazepane-1-carbonyl)phenyl)furan-2-yl)methylene)indolin-2-one, 4a} and its desmethylated precursor N-desmethyl-CX-6258 {(E)-3-((5-(3-(1,4-diazepane-1-carbonyl)phenyl)furan-2-yl ...
Gao, Mingzhang   +4 more
core   +1 more source

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