Results 11 to 20 of about 3,259,253 (212)

Radioligand Assay-Based Detection of Antibodies against SARS-CoV-2 in Hospital Workers Treating Patients with Severe COVID-19 in Japan [PDF]

Viruses, 2021
This study aimed to clarify whether infection by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is prevalent among the staff of a hospital providing treatment to patients with severe coronavirus disease 2019 (COVID-19) using radioligand ...
Hidenori Matsunaga, Akiko Makino, Yasuhiro Kato, Teruaki Murakami, Yuta Yamaguchi, Atsushi Kumanogoh, Yuichiro Oba, Satoshi Fujimi, Tomoyuki Honda, Keizo Tomonaga   +9 more
doaj   +2 more sources

A radioligand binding assay for the insulin-like growth factor 2 receptor.

PLoS ONE, 2020
Insulin-like growth factors 2 and 1 (IGF2 and IGF1) and insulin are closely related hormones that are responsible for the regulation of metabolic homeostasis, development and growth of the organism.
Pavlo Potalitsyn, Irena Selicharová, Kryštof Sršeň, Jelena Radosavljević, Aleš Marek, Kateřina Nováková, Jiří Jiráček, Lenka Žáková   +7 more
doaj   +2 more sources

Characterization of substrates and inhibitors of the human heterodimeric transporter 4F2hc-LAT1 using purified protein and the scintillation proximity radioligand binding assay [PDF]

Frontiers in Physiology, 2023
Amino acids have diverse and essential roles in many cellular functions such as in protein synthesis, metabolism and as precursors of different hormones.
Satish Kantipudi, Daniel Harder, Dimitrios Fotiadis   +2 more
doaj   +3 more sources

Methods for assessing binding of a small-molecule radioligand to soluble enzyme isocitrate dehydrogenase 1 variants [PDF]

EJNMMI Radiopharmacy and Chemistry
Background Isocitrate dehydrogenase 1 (IDH1) is a cytosolic NADP+-dependent enzyme involved in cellular redox homeostasis and 2-oxoglutarate (2-OG) metabolism.
Winnie Deuther-Conrad, Thu Hang Lai, Andreas Maurer, Barbara Wenzel   +3 more
doaj   +2 more sources

Fully Automated Radioligand Binding Filtration Assay for Membrane-Bound Receptors

BioTechniques, 2002
Here we describe a fully automated, hands-free radioligand filtration binding assay for dopamine D3 receptors. Three separate instruments were linked in tandem to perform the following operations: The Genmate and Genesis were linked to perform liquid ...
A. Shrikhande, C. Courtney, D. Smith, M. Melch, M. McConkey, J. Bergeron, Stephen K-F. Wong   +6 more
doaj   +2 more sources

Quantitation of the Folate Binding Protein in Human Cerebrospinal Fluid by an Enzyme-linked Immunosorbent Assay (ELISA)

Pteridines, 1989
An enzyme-linked immunosorbent assay (ELISA) was calibrated and used for quantitation of the folate binding protein in human cerebrospinal fluid. The precision of the assay in terms of the coefficient of variation was 6.3% intra-assay (10 replicate ...
Ingemann Hansen Steen, Holm Jan, Høier-Madsen Mimi   +2 more
doaj   +2 more sources

Paltusotine versus octreotide: different effects on radioligand uptake in neuroendocrine tumours [PDF]

Endocrine Oncology
Objective: Somatostatin receptor analogues are well-established in the treatment of metastatic gastro-enteropancreatic neuroendocrine tumours (GEP-NETs), especially for symptom control in patients with the carcinoid syndrome, and to control tumour growth.
Katharina Wang, Christoph J Auernhammer, Simon Lindner, Mathias Zacherl, Rudolf A Werner, Julian Maurer, Lea Peischer, Julia Hamati, Maximilian P Hungbauer, Thomas Knösel, Astrid Reul, Elena Kuzmenko, Diana Vetter, José Oberholzer, Umberto Maccio, Felix Beuschlein, Martin Reincke, Constanze Hantel, Karel Pacak, Ashley B Grossman, Kathrin Zitzmann, Svenja Nölting   +21 more
doaj   +2 more sources

Preliminary Screening of South African Plants for Binding Affinity to the Serotonin Reuptake Transporter and Adenosine A₁/A_2A Receptors

Scientia Pharmaceutica, 2023
In South African traditional medicine, Gomphocarpus fruticosus (L.) W.T. Aiton, Hypoxis hemerocallidea Fisch. & C.A. Mey., and Leonotis leonurus. (L.) R.Br.
Andisiwe Mnqika, Adeyemi O. Aremu, H. D. Janse van Rensburg, Makhotso Lekhooa   +3 more
doaj   +1 more source

Reliability of the thyroid stimulating hormone receptor antibodies level determination in diagnosing and prognosing of immunogenic hyperthyroidism [PDF]

Vojnosanitetski Pregled, 2009
Background/Aim. Graves disease (GD) is defined as hyperthyroidism with diffuse goiter caused by immunogenic disturbances. Antibodies to the thyroid stimulating hormone (TSH) receptors of thyroid gland (TRAb) have crucial pathogenetic importance in the ...
Aleksić Aleksandar Z., Aleksić Željka P., Mitov Vladimir M., Jović Miljan J.   +3 more
doaj   +1 more source

A High-Affinity ⁶⁴Cu-Labeled Ligand for PET Imaging of Hepsin: Design, Synthesis, and Characterization

Pharmaceuticals, 2022
Hepsin, a cell surface serine protease, is a potential biomarker for the detection of prostate cancer due to its high expression in prostate cancer but not in normal prostate.
Ji-Hun Park, Xuran Zhang, Hyunsoo Ha, Jung Young Kim, Joon Young Choi, Kyung-Han Lee, Youngjoo Byun, Yearn Seong Choe   +7 more
doaj   +1 more source