Results 31 to 40 of about 22,462 (308)
Stability of Silver Nanoparticles as Imaging Materials [PDF]
Determining the stability of silver nanoparticles is a very important process. It was associated with unwanted metal charge and materials properties. Therefore, we studied to synthesis and stability of silver nanoparticles (AgNPs).
Umi Nur Sholikhah+7 more
doaj +1 more source
Coded Aperture and Compton Imaging for the Development of $^{225}$Ac-based Radiopharmaceuticals [PDF]
Targeted alpha-particle therapy (TAT) has great promise as a cancer treatment. Arguably the most promising TAT radionuclide that has been proposed is $^{225}$Ac. The development of $^{225}$Ac-based radiopharmaceuticals has been hampered due to the lack of effective means to study the daughter redistribution of these agents in small animals at the ...
arxiv
Non-invasive imaging of cyclooxygenase-2 (COX-2) by radiolabeled ligands is attractive for the diagnosis of cancer, and novel highly affine leads with optimized pharmacokinetic profile are of great interest for future developments.
Markus Laube+3 more
doaj +1 more source
Monte Carlo-based estimation of patient absorbed dose in 99mTc-DMSA, -MAG3, and -DTPA SPECT imaging using the University of Florida (UF) phantoms [PDF]
SPECT imaging is one of the common modalities used to examine kidney disease. The radiopharmaceuticals such as 99mTc-MAG3, 99mTc-DTPA, and 99mTc-DMSA are commonly employed for pediatric patients. It is generally accepted that children organs are more sensitive to radiation than adults, due to their growth rate.
arxiv
Experimental evidence has associated receptor tyrosine kinase EphB4 with tumor angiogenesis also in malignant melanoma. Considering the limited in vivo data available, we have conducted a systematic multitracer and multimodal imaging investigation in ...
Christin Neuber+6 more
doaj +1 more source
Potential Applications of Artificial Intelligence and Machine Learning in Radiochemistry and Radiochemical Engineering [PDF]
Artificial intelligence and machine learning are poised to disrupt PET imaging from bench to clinic. In this perspective we offer insights into how the technology could be applied to improve the design and synthesis of new radiopharmaceuticals for PET imaging, including identification of an optimal labeling approach as well as strategies for ...
arxiv
Role of AI in Theranostics: Towards Routine Personalized Radiopharmaceutical Therapies [PDF]
We highlight emerging uses of artificial intelligence (AI) in the field of theranostics, focusing on its significant potential to enable routine and reliable personalization of radiopharmaceutical therapies (RPTs). Personalized RPTs require patient-individual dosimetry calculations accompanying therapy.
arxiv
Radiation therapy (RT) evolved to be a primary treatment modality for cancer patients. Unfortunately, the cure or relief of symptoms is still accompanied by radiation-induced side effects with severe acute and late pathophysiological consequences ...
Markus Laube+2 more
doaj +1 more source
Close contact restriction periods for patients who received iodine-131 therapy for differentiated thyroid cancer [PDF]
Objective. Patients treated with radionuclide therapy may require restrictions on certain activities for a period of time following treatment to optimise protection of the public and ensure the legal dose limit is not exceeded. Software may be used to calculate necessary restriction periods for an individual based on longitudinal dose rate measurements
arxiv +1 more source
Introduction: The crucial step in preclinical process of radiopharmaceutical production is internal dosimetry evaluation by different ways to realize radiobiological dose-response relationships and to extract the results for clinical use.
Zahra Pourhabib, Hassan Ranjbar
doaj