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International Journal of Radiation Oncology*Biology*Physics, 2006
The term "naked" radiopharmaceuticals, more appropriately, "unbound" radiopharmaceuticals, refers to any radioisotope used for clinical research or clinical purposes that is not attached to a chemical or biological carrier, and that localizes in various tissues because of a physiologic or chemical propensity/affinity, or secondary to focal anatomic ...
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The term "naked" radiopharmaceuticals, more appropriately, "unbound" radiopharmaceuticals, refers to any radioisotope used for clinical research or clinical purposes that is not attached to a chemical or biological carrier, and that localizes in various tissues because of a physiologic or chemical propensity/affinity, or secondary to focal anatomic ...
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A New Radiopharmaceutical for Placentography
Radiology, 1964Radioisotopic placentography requires accurate localization of the maternal component of placental circulation by detection of a circulating radionuclide confined to the maternal intravascular space. Sodium-24 chloride was the tracer first employed in placentography (2) but its rapid extravascular diffusion was disadvantageous.
Elmer E. Stickley +2 more
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2019
Copper (Cu) is a transition metal with atomic number 29, involved in several physiological processes, being cofactor for numerous enzymes, such as the “Cu/Zn superoxide dismutase,” “cytochrome-C-oxidase,” “tyrosinase,” “ceruloplasmin,” and other proteins.
Antonio Bagnato +6 more
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Copper (Cu) is a transition metal with atomic number 29, involved in several physiological processes, being cofactor for numerous enzymes, such as the “Cu/Zn superoxide dismutase,” “cytochrome-C-oxidase,” “tyrosinase,” “ceruloplasmin,” and other proteins.
Antonio Bagnato +6 more
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Drug interactions with radiopharmaceuticals
European Journal of Nuclear Medicine, 1994Considerable information on documented drug and radiopharmaceutical interactions has been assembled in a tabular form, classified by the type of nuclear medicine study. The aim is to provide a rapid reference for nuclear medicine staff to look for such interactions.
Stuart Hesslewood, Emmeline Leung
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Radiochemistry and radiopharmaceuticals
Annual Reports Section "A" (Inorganic Chemistry), 2006Following last year’s precedent this section of Annual Reports will review not only recent progress in radiochemistry, including isotope production and environmental aspects, but also in the production of radiopharmaceuticals and their use in nuclear medicine for imaging.
David S. Urch, Michael J. Welch
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Anti-cancer radiopharmaceuticals
Anti-Cancer Drugs, 1991Therapeutic nuclear medicine is rapidly developing as an additional treatment modality in oncology. A great variety of specific tumor-seeking radiopharmaceuticals is applied both for diagnostic scintigraphy and treatment, using multiple routes and mechanisms to target radionuclides at tumors.
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Novel Radiopharmaceuticals for Therapy
2016In the era of personalizedmedicine, "target radionuclide therapy" (TRT) is designed to damage only the cancerous cells while sparing unnecessary damage to the adjacent healthy cells/tissues. Unlike conventional external beam radiation therapy, TRT is intended to cause less or no collateral damage to normal tissues, as it aims at achieving targeted drug
Guidoccio F. +4 more
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Characteristics of Specific Radiopharmaceuticals
1979In Chapter 6 the general principles of labeling methods were discussed, particularly iodination and 99mTc-labeling, and kit preparation of 99mTc-radiopharmaceuticals was described. In this chapter the basic principles of preparation, labeling yield, stability, storage conditions, and other characteristics of several radiolabeled compounds most commonly
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Radiopharmaceuticals and Methods of Radiolabeling [PDF]
, 1992 A radiopharmaceutical is a radioactive compound used for the diagnosis and therapeutic treatment of human diseases. In nuclear medicine nearly 95% of the radiopharmaceuticals are used for diagnostic purposes, while the rest are used for therapeutic treatment. Radiopharmaceuticals usually have minimal pharmacologic effect, because in most cases they are
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