Results 101 to 110 of about 7,465 (248)

47Sc as useful β–-emitter for the radiotheragnostic paradigm: a comparative study of feasible production routes

EJNMMI Radiopharmacy and Chemistry, 2017
Background Radiotheragnostics makes use of the same molecular targeting vectors, labeled either with a diagnostic or therapeutic radionuclide, ideally of the same chemical element.
Katharina A. Domnanich, Cristina Müller, Martina Benešová, Rugard Dressler, Stephanie Haller, Ulli Köster, Bernard Ponsard, Roger Schibli, Andreas Türler, Nicholas P. van der Meulen   +9 more
doaj   +1 more source

PET Imaging in Cardiac Sarcoidosis: A Narrative Review with Focus on Novel PET Tracers

, 2021
Sarcoidosis is a multi-system inflammatory disease characterized by the development of inflammation and noncaseating granulomas that can involve nearly every organ system, with a predilection for the pulmonary system.
Martin Rodriguez-Porcel, Petar Saric, Kathleen Young, Panithaya Chareonthaitawee   +3 more
core   +1 more source

A consensus roadmap for post‐traumatic epilepsy: Clinical biomarkers, research priorities, policy barriers, and pathways to interventional trials

Epilepsia, EarlyView.
Abstract Understanding the mechanisms underlying post‐traumatic epilepsy (PTE) following traumatic brain injury (TBI), and developing strategies to prevent or modify its progression, has been the focus of large collaborative efforts within the epilepsy and TBI research communities for over a decade.
Elisa R. Zanier, Ilaria Lisi, Elaine K. O'Loughlin, Federico Moro, Edilberto Amorim, David L. Brody, Daniel J. Correa, Dominique Duncan, Pavel Klein, Firas H. Kobeissy, Wolfgang Löscher, Edward J. Needham, Asla Pitkänen, Mary Jo Pugh, Jack Somers, Annamaria Vezzani, Amy K. Wagner, Laura S. Lubbers, International Conference on PTE Attendees, Denes Agoston, Edilberto Amorim, Sneha Anand, Hibah Awwad, Ginevra Bayon, Naima Belhachemi, Akash Bera, Costanza Bertani, Guido Bertolini, David L. Brody, Serena Brusatori, Francesca Buffelli, Aurora Chiapperini, Mara Chioccola, Severn Churn, Daniel J. Correa, Ramon Diaz‐Arrastia, Chris Dulla, Dominique Duncan, Chiara Ferlito, Aristea Galanopoulou, Angela Galic, Heidi Matos Galicia, Bin Gu, William Haskins, Victoria Johnson, Nigel Jones, Lowie Joseph, Pavel Klein, Firas Kobaissy, Ilaria Lisi, David Loane, Luther Loose, Laura S. Lubbers, Wolfgang Löscher, Edoardo Mazzone, Melissa Miller, Federico Moro, Edward J. Needham, Irma Wati Ngadimon, Terence O’Brien, Elaine K. O’Loughlin, Asla Pitkanen, Mary Jo Pugh, Teresa Giovanna Ravizza, Giuseppe Remuzzi, Massimo Rizzi, Rossella Di Sapia, Tawfeeq Shekh‐Ahmad, Doug Smith, Jack Somers, Kevin Staley, Francesca Tribuzio, Alexandra Ulyanova, Gloria Vegliante, Annamaria Vezzani, Joost Wagenaar, Amy K. Wagner, Kevin W. Wang, Justin Weppner, Peter J. West, Karen Wilcox, John Wolf, Elisa R. Zanier   +82 more
wiley   +1 more source

Relaxed fibronectin: a potential novel target for imaging endometriotic lesions

EJNMMI Research
Background Endometriosis is characterized by the ectopic occurrence of endometrial tissue. Though considered benign, endometriotic lesions possess tumor-like properties such as tissue invasion and remodeling of the extracellular matrix.
Belinda Trachsel, Stefan Imobersteg, Giulia Valpreda, Gad Singer, Regula Grabherr, Mark Ormos, Irene A. Burger, Rahel A. Kubik-Huch, Roger Schibli, Viola Vogel, Martin Béhé   +10 more
doaj   +1 more source

Synthesis and Preliminary Evaluation of a 2-Oxoquinoline Carboxylic Acid Derivative for PET Imaging the Cannabinoid Type 2 Receptor

Pharmaceuticals, 2014
Cannabinoid receptor subtype 2 (CB2) has been shown to be up-regulated in activated microglia and therefore plays an important role in neuroinflammatory and neurodegenerative diseases such as multiple sclerosis, amyotrophic lateral sclerosis and ...
Linjing Mu, Roger Slavik, Adrienne Müller, Kasim Popaj, Stjepko Čermak, Markus Weber, Roger Schibli, Stefanie D. Krämer, Simon M. Ametamey   +8 more
doaj   +1 more source

Hepatitis C virus infections from a contaminated radiopharmaceutical used in myocardial perfusion studies

, 2006
Context: Nuclear pharmacies prepare radiopharmaceutical products for use in common diagnostic procedures, including myocardial perfusion studies. Hepatitis C virus (HCV) transmission has not been reported previously in the setting of nuclear imaging ...
Patel, Priti R., Myers, Robert A., Blythe, David, Fiore, Anthony E., Krick, John P., Roup, Brenda J., Edwards, Leslie, Larson, A. Kirsten, Castel, Amanda D., Farrell, Katherine P., Nainan, Omana, Roche, Jeffrey C., Ganova-Raeva, Lilia M.   +12 more
core   +1 more source

A New Class of PSMA-617-Based Hybrid Molecules for Preoperative Imaging and Intraoperative Fluorescence Navigation of Prostate Cancer

, 2022
The development of PSMA-targeting low-molecular-weight hybrid molecules aims at advancing preoperative imaging and accurate intraoperative fluorescence guidance for improved diagnosis and therapy of prostate cancer.
Ulrike Bauder-Wüst, Klaus Kopka, Ann-Christin Eder, Matthias Eder, Nils Steinacker, Lisa-Charlotte Domogalla, Uwe Haberkorn, Jana Schmidt, Mareike Roscher, Martin Schäfer, Jessica Matthias   +10 more
core   +1 more source

Radiolabeled Coordination Polymer‐Loaded Microneedles for Synergistic Melanoma Brachytherapy–Immunotherapy via STING Activation and Pyroptosis

Exploration, EarlyView.
We developed a dissolvable microneedle patch that locally delivers a radiolabeled coordination polymer designed to simultaneously destroy tumor cells and stimulate antitumor immunity through STING activation and pyroptosis. This strategy significantly inhibited melanoma growth and improved the effectiveness of immune checkpoint therapy, highlighting a ...
Pian Yu, Shijun Xiang, Lu Hao, Jessica C. Hsu, Kaixuan Li, Rongxuan Yan, Ming Zhou, Yongxiang Tang, Ying Peng, Weibo Cai, Cong Peng, Peng Liu, Shuo Hu   +12 more
wiley   +1 more source

Optimized (68)Ga-Labeled Urea-Based PSMA-Targeted PET Tracers for Prostate Cancer

, 2022
Prostate-specific membrane antigen (PSMA)-targeting radiopharmaceuticals have become some of the most promising tools for the diagnosis and therapy prostate cancer (PCa).
Wu, Yitian, Tian, Jiahe, Yitian Wu, Xiaojun Zhang, Ying Zhang, Zhang, Ying, Jiahe Tian, Xu, Baixuan, Jinming Zhang, Zhang, Jinming, Zhang, Xiaojun, Baixuan Xu   +11 more
core   +1 more source

c‐Met‐Targeted Imaging Agents: Progress and Challenges

iRADIOLOGY, EarlyView.
This review summarizes recent advances in c‐Met‐targeted imaging probes, including hepatocyte growth factor (HGF) ligands, antibodies, peptides, and small molecules across magnetic resonance imaging (MRI), positron emission tomography (PET), single‐photon emission computed tomography (SPECT), and optical imaging modalities.
Yonghao Li, Aiyan Ji, Qihang Ding, Hongyue Lou, Zhen Cheng   +4 more
wiley   +1 more source