Results 81 to 90 of about 6,328 (205)
Abstract Background Serum neurofilament light chain (NfL) levels, a marker of axonal damage, are generally elevated in neurodegenerative conditions, but results in idiopathic Parkinson's disease (iPD) have been inconsistent. The p.A53T SNCA mutation usually leads to a severe form of PD.
Nikolaos Papagiannakis +213 more
wiley +1 more source
Development of amphiphilic self-assembled nucleolipid as BBB targeting probe based on SPECT
Several approaches have been utilised to deliver therapeutic nanoparticles inside the brain but rendered by certain limitation such as active efflux, non-stability, toxicity of the nanocarrier, transport, physicochemical properties and many more. In this
Swastika Tiwari +5 more
doaj +1 more source
Several studies showed that [11C]ABP688 binding is altered following drug-induced perturbation of glutamate levels in brains of humans, non-human primates and rats.
Adrienne Müller Herde +5 more
doaj +1 more source
Abstract Over recent years, several deep learning (DL) models have been presented to predict colorectal cancer (CRC) patient survival directly from haematoxylin and eosin (H&E)‐stained routine whole‐slide images (WSIs). Unlike traditional studies that rely on manually defined histopathological features, weakly supervised DL allows training directly on ...
Nic G Reitsam +23 more
wiley +1 more source
Production and quality control of radiopharmaceuticals in “Vinča” Institute of Nuclear Sciences
9th Balkan congress of nuclear medicine, May 12-14, 2022., Vrdnik ...
Vukadinović, Aleksandar +8 more
openaire +1 more source
ABSTRACT Background To compare choline PET‐CT and PSMA PET‐CT in a cohort of patients with high‐risk localized prostate cancer, assessing the diagnostic capacity of both tests. whose therapeutic approach could be modified based on the results. Methods An observational study was conducted in 116 patients with high‐risk prostate cancer between January ...
M. A. Tárraga‐Honrubia +5 more
wiley +1 more source
Precisely engineered heterostructured metal oxide‐based MO2 / CaF2 (M = Ce, Th, U) core‐shell nanocrystals are synthesized with atomic‐level control over size, shell thickness, and interface coherence, expanding heterostructure design principles to cerium oxide and actinide oxide systems for the first time.
Dejing Meng +14 more
wiley +2 more sources
2D van der Waals System Integrated with Targeting Radio‐Diagnostic and Imaging Functions
Layered double hydroxide (LDH) nanoplates were engineered for tumor‐targeted imaging and therapy. By exploiting folate receptor (FR) expression levels, the system achieves selective tumor accumulation and high‐resolution dual PET/fluorescence (PET/FL) imaging.
Sairan Eom +6 more
wiley +1 more source
Trends in nuclear medicine and the radiopharmaceutical sciences in oncology
Although the promise of radionuclides for the diagnosis and treatment of disease was recognised soon after the discovery of radioactivity in the late 19th century, the systematic use of radionuclides in medicine only gradually increased over the subsequent hundred years.
Scott, Andrew M. +17 more
openaire +1 more source
Cutting‐edge advances in bicyclic peptide‐based radiotracers for cancer imaging and theranostics
Abstract Along with successful clinical approval of radiopharmaceuticals targeting somatostatin receptor subtype 2 and prostate‐specific membrane antigen, peptide‐based radiotracers have garnered the increasing attention in cancer imaging and theranostics. As a newly emerging targeting ligand in recent years, bicyclic peptides have demonstrated immense
Hengyi Ou, Xiaobo Wang, Fei Kang
wiley +1 more source

