Results 71 to 80 of about 30,881 (212)

Microbiota-mediated modulation of radiosensitivity: mechanisms and therapeutic prospects of oral and gut microbiota, metabolites, and probiotics

Frontiers in Microbiology
Radiotherapy is a cornerstone of comprehensive cancer treatment, yet its efficacy and toxicity exhibit considerable interindividual variation. Recent evidence highlights the microbiome—the collective genomes and metabolic products of symbiotic ...
Baixue Wu, Anqi Zhao, Wenlu Chen, Yuying Zhou, Wenbo Zhang, Yiwen Zhang, Qing Hou, Ningning Yao, Shuangping Zhang, Jianchun Duan, Jianchun Duan, Ning Li, Jianzhong Cao   +12 more
doaj   +1 more source

Advances and Perspectives in Graphene‐Based Quantum Dots Enabled Neuromorphic Devices

Advanced Science, EarlyView.
Graphene‐based QDs are zero‐dimensional carbon nanomaterials with pronounced quantum confinement and tunable electronic structures. Herein, we summarize their synthesis strategies and functionalization methods, and highlight their functional roles and operating mechanisms in devices, as well as recent advances in neuromorphic electronics. We anticipate
Yulin Zhen, Wei Zeng, Zherui Zhao, JiYu Zhao, Ziyan Huang, Zhuo Chen, Kui Zhou, Guanglong Ding, Su‐Ting Han, Ye Zhou   +9 more
wiley   +1 more source

Retina‐Inspired Bi‐Based Terahertz Photonic Neuromorphic Devices

Advanced Science, EarlyView.
Combined with effective band alignment and substrate engineering, bismuth materials are introduced to form terahertz photonic bio‐inspired devices with picosecond short‐term plasticity to enable multi‐scene visual perception. Thus obtained hardware through the terahertz optical neural network (THz‐ONN) demonstrates high recognition accuracy, providing ...
Pujing Zhang, Donggang Xie, Longyu Shi, Mengyuan Wang, Huiwen Shi, Yu Wu, Menglei Li, Guangwei She, Peijie Wang, Wensheng Shi, Cunlin Zhang, Kuijuan Jin, Guozhen Yang, Qingli Zhou, Chen Ge   +14 more
wiley   +1 more source

Neuromorphic Near‐Sensor and In‐Sensor Computing Enabled by Next‐Generation Material‐Based Sensors

Advanced Science, EarlyView.
This Review presents a structural framework that classifies neuromorphic sensing into near‐sensor and in‐sensor architectures, clarifying physical coupling between sensing and computation. The framework connects neural and synaptic device functions with recent advances in optical, mechanical, and chemical sensing, compares energy consumption and ...
Su Yeon Jung, Gwang Ya Kim, Sejin Kim, Hyunjong Seo, Se Gi Lee, Sang Min Won, Dongjoon Rhee, Joohoon Kang   +7 more
wiley   +1 more source

Review of Gastrointestinal Capsule Robots: Materials, Actuation, Diagnostics, and Therapeutics

Advanced Science, EarlyView.
This review examines gastrointestinal capsule robots through a systems engineering lens, covering shell materials, actuation and localization strategies, diagnostic modalities, therapeutic interventions, and commercialization status. By mapping the complete technological chain from fabrication to clinical deployment, this work identifies critical gaps ...
Zengsheng Li, Zhongguo Ren, Yiliang Lin, Xianfeng Xia, Tianlong Li, Kai Fung Chan, Philip Wai Yan Chiu, Wei Peng Yong, Mengmeng Sun   +8 more
wiley   +1 more source

LncRNA EGFR-AS1 inhibits ferroptosis to reduce radiosensitivity of cervical cancer through the m6A/IGF2BP3/APAF1 axis

BMC Cancer
Background Cervical cancer is a significant concern among women, and radioresistance is a key obstacle in its treatment. Ferroptosis is a new way of death, which offers a fresh idea for tumor radiotherapy.
Xianglong Chen, Jingyu Li, Yujie Sun, Zhaoyu Ye, Man Long, Junguo Bu, Zirong Fan, Zhaojing Jiang   +7 more
doaj   +1 more source

Detection of radiosensitive subpopulations ex-vivo with Raman microspectroscopy

Frontiers in Oncology
Although significant advances in understanding the molecular drivers of acquired and inherited radiosensitivity have occurred in recent decades, a single analytical method which can detect and classify radiosensitivity remains elusive.
Aidan D. Meade, Adrian Maguire, Adrian Maguire, Jane Bryant, Daniel Cullen, Daniel Cullen, Dinesh Medipally, Dinesh Medipally, Lisa White, Lisa White, John Armstrong, Mary Dunne, Emma Noone, Shirley Bradshaw, Marie Finn, Aoife M. Shannon, Orla L. Howe, Orla L. Howe, Fiona M. Lyng, Fiona M. Lyng   +19 more
doaj   +1 more source

Unipolar Barrier Near‐Infrared 2D Photodetectors for 3D Image Sensors

Advanced Science, EarlyView.
A MoTe2/WSe2/Cl–SnSe2 unipolar barrier photodetector is demonstrated, in which the WSe2 layer effectively blocks majority‐carrier injection, yielding suppressed dark current and enhanced near‐infrared (NIR) sensing. The device achieves high detectivity, a wide linear dynamic range, and fast response under 1310 nm illumination, enabling high‐fidelity 3D
Jung Pyo Hong, Sang‐Jun Kim, Jisu Jang, Je‐Jun Lee, Seong‐Jun Han, Eungseon Yeon, Jung Woo Kim, Jongtae Ahn, Sang Yeon Kim, Hyun Woo Ko, Sunghyun Han, Seung Ah Lee, Paul Hongsuck Seo, Young‐Woo Suh, Kimoon Lee, Gunuk Wang, Dong‐Guang Zheng, Sunghee Hong, Sangin Hahn, Seon Kyu Yoon, Min‐Chul Park, Do Kyung Hwang   +21 more
wiley   +1 more source

Metabolic Reprogramming in Glioblastoma Stem Cells Promotes Radiation Resistance Through a H3K18la/USP30/MBOAT2 Axis

Advanced Science, EarlyView.
LDHA‐driven lactate production in mesenchymal glioma stem cells promotes p300‐dependent H3K18 lactylation, activates USP30 transcription, and stabilizes MBOAT2 to remodel phosphatidylethanolamines toward ferroptosis‐resistant PE‐MUFA species. Disrupting this metabolic–epigenetic–lipid circuit enhances ferroptosis and sensitizes glioblastoma to ...
Zong Miao, Wei Gu, Yimin Ren, Chenfei Lu, Wanzhi Cai, Junnan Lu, Zhongyuan Bao, Yanan Zhou, Rong Li, Ke Jin, Chao Chen, Hongxiang Wang, Lei Xu, Juxiang Chen   +13 more
wiley   +1 more source

Exploring the Role of p53 in Radiosensitivity: A Key Player in Cancer Therapy

Radiation
Radiotherapy remains a cornerstone in cancer treatment, leveraging ionizing radiation to eradicate malignant cells. Its efficacy, however, is frequently challenged by the heterogeneous sensitivity of tumors and surrounding tissues to radiation. Therefore,
Tusher- Al-Arafat, Aihong Mao, Takanori Katsube, Bing Wang   +3 more
doaj   +1 more source