Results 1 to 10 of about 26,475 (236)
Life, 2022 Radiotherapy is a major therapeutic strategy for lung cancer, and radiation resistance (radioresistance) is an important cause of residual and recurring cancer after treatment. However, the mechanism of radioresistance remains unclear.
Shunlong Wu +3 more
doaj +2 more sources
Long Noncoding RNAs Regulate the Radioresistance of Breast Cancer
Analytical Cellular Pathology, 2021 Breast cancer (BRCA) has severely threatened women’s health worldwide. Radiotherapy is a treatment for BRCA, which applies high doses of ionizing radiation to induce cancer cell death and reduce disease recurrence.
Zhifeng Li +4 more
doaj +2 more sources
Frontiers in Oncology, 2022 Radiotherapy exerts a crucial role in curing cancer, however, its treatment efficiency is mostly limited due to the presence of radioresistance. Epithelial-to-mesenchymal transition (EMT) is a biological process that endows the cancer cells with invasive
Lili Qiao, Fengjun Liu, Guodong Deng
exaly +3 more sources
Review: Mechanisms and Perspective Treatment of Radioresistance in Non-Small Cell Lung Cancer
Frontiers in Immunology, 2023 Radiotherapy is the major treatment of non-small cell lung cancer (NSCLC). The radioresistance and toxicity are the main obstacles that leading to therapeutic failure and poor prognosis.
Ting Zhou +15 more
exaly +3 more sources
PPP2R2C confers radioresistance in nasopharyngeal carcinoma by suppressing ferroptosis via RPS27L stabilization [PDF]
Cell Death and DiseaseRadiotherapy resistance remains a major obstacle in nasopharyngeal carcinoma (NPC). This study delineates the role of protein phosphatase 2 regulatory subunit B gamma (PPP2R2C) in NPC radioresistance and its underlying mechanism to identify therapeutic ...
Jianbo Fang +13 more
doaj +2 more sources
Recent progress of the tumor microenvironmental metabolism in cervical cancer radioresistance
Frontiers in Oncology, 2022 Radiotherapy is widely used as an indispensable treatment option for cervical cancer patients. However, radioresistance always occurs and has become a big obstacle to treatment efficacy.
Junying Zhou +9 more
doaj +1 more source
The Mechanism of Long Non-coding RNA in Cancer Radioresistance/Radiosensitivity: A Systematic Review
Frontiers in Pharmacology, 2022 Background and purpose: Radioresistance remains a significant challenge in tumor therapy. This systematic review aims to demonstrate the role of long non-coding RNA (lncRNA) in cancer radioresistance/radiosensitivity.Material and methods: The electronic ...
Wenhan Wu, Shijian Zhang, Jia He
doaj +1 more source
Frontiers in Bioscience-Landmark, 2023 Background: Breast cancer poses severe threats to human health as radioresistance becomes increasingly prevalent. The mechanisms of radioresistance are hard to expound completely.
Yingxia Ying +6 more
doaj +1 more source
Kaohsiung Journal of Medical Sciences, 2023 Prostate cancer is one of the most common cancers in men. This study was conducted to investigate the role of euchromatic histone lysine methyltransferase 2 (EHMT2) and endoplasmic reticulum protein 29 (ERP29) in the progression of radioresistance in ...
Zhi‐Chao Huang +4 more
doaj +1 more source
LINC01094 triggers radio-resistance in clear cell renal cell carcinoma via miR-577/CHEK2/FOXM1 axis
Cancer Cell International, 2020 Background Radioresistance is an obstacle to limit efficacy of radiotherapy. Meanwhile, long non-coding RNAs (lncRNAs) have been reported to affect radioresistance. Here, we aimed to investigate lncRNAs involving radioresistance development of clear cell
Yufeng Jiang +5 more
doaj +1 more source