Results 111 to 120 of about 14,471 (229)
Cascade decay of single vacancies in 1s, 2s, 2p1/2, and 2p3/2 subshells of an isolated platinum atom are simu- lated by the method of construction and analysis of the cascade decay trees. The yields of final ions and the spectra of cascade electrons and
A.G. Kochur +3 more
doaj +1 more source
Protein Lactylation in Cancer: From Mechanisms to Therapy
Increased glycolysis and lactate accumulation promote histone and nonhistone protein lactylation, linking tumor metabolic reprogramming to treatment adaptation. Lactylation enhances DNA repair, suppresses antitumor immunity, strengthens antioxidant defenses, and facilitates cell‐cycle checkpoint escape, collectively promoting resistance to chemotherapy,
Wentian Huang +8 more
wiley +1 more source
Possible relations between hyperthermic inactivation of α and β DNA polymerase activity and hyperthermic cell killing or hyperthermic radiosensitization were investigated. Ehrlich Ascites Tumor (EAT) cells and HeLa S3 cells were treated with fractionated
Jorritsma, J. B. M. +3 more
core +1 more source
Theranostic Applications of Gold Nanoparticles in Radiosensitization and X-Ray Fluorescence Computed Tomography Imaging [PDF]
In recent years gold nanoparticles (AuNPs) have become a very intriguing tool for potential use in cancer therapy and cancer imaging. Many publications show AuNPs ability to improve radiation therapy (RT) in silico, in vitro, and in vivo by physical ...
Schmidt, Ryder
core +3 more sources
Radiosensitization: enhancing the radiation inactivation of foodborne bacteria
International audienceIrradiation of meat products to kill pathogens can be limited by radiation-induced detriment of sensory quality. Since such detriment is directly related to dose, one approach to reduce it is by devising means to lower the dose of ...
Ouattara, B. +3 more
core +1 more source
Inducing Ferroptosis: Sensitization Strategy for Radiotherapy and Its Application
Ferroptosis is a novel regulated cell death caused by the accumulation of iron-dependent ROS and excessive local lipid peroxides in the membrane, widely involved in various physiological and pathological processes.
Xun Chen +3 more
doaj +1 more source
Targeting mitochondria as a potential therapeutic strategy against radioresistance in cancer
Radioresistance remains a major barrier to effective cancer therapy, contributing to tumor persistence, recurrence, and poor clinical outcomes. Increasing evidence identifies mitochondria as central regulators of radiation response through their ...
Nazia Nazam +7 more
doaj +1 more source
Hypoxia-induced radioresistance remains a major obstacle in non-small cell lung cancer (NSCLC) radiotherapy. This study investigates whether artificially activating mitochondrial reverse electron transfer (RET) can enhance radiosensitivity in NSCLC by ...
Cuilan Hu +8 more
doaj +1 more source
Golden era of radiosensitizers
The past 30 years have brought undeniable progress in medicine, biology, physics, and research. Knowledge of the nature of the human body, diseases, and disorders has been constantly improving, and the same is true regarding their treatment and diagnosis. One of the greatest advances in recent years has been the introduction of nanoparticles (NPs) into
Čížková, Jana +6 more
openaire +4 more sources

