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Radiosensitization and Nanoparticles
2015Nanomaterials have been shown to have physical and chemical properties that have opened new avenues for cancer diagnosis and therapy. Nanoconstructs that enhance existing treatments for cancer, such as radiation therapy, are being explored in several different ways. Two general paths toward nanomaterial-enabled radiosensitization have been explored: (1)
Tatjana, Paunesku +3 more
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Chromosomes, Cancer, and Radiosensitivity
American Journal of Clinical Oncology, 1982Some specific chromosomal abnormalities are associated with certain cancers. The earliest description of such a specific association is the one of the Philadelphia chromosome and myelogenous leukemia (1960). Other congenital karyotype abnormalities are associated with specific cancers. Examples of these are Down's syndrome with leukemia and Klinefelter'
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Radiosensitivity of capillary endothelium
The British Journal of Radiology, 1973Abstract Starting with a subcutaneous air pouch in the rat, a system was developed in which a thin sheet of connecting tissue was partially separated from its surroundings. In a small area that was depleted of blood vessels by freezing, vascular proliferation was induced by the application of a stimulus employing uric acid and lithium lactate.
H S, Reinhold, G H, Buisman
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[Radiosensitizer: hypoxic cell radiosensitizer].
Gan to kagaku ryoho. Cancer & chemotherapy, 1989There is a world-wide demand for a clinically usable sensitizer for radio-resistant hypoxic cells. After unsuccessful clinical trials of misonidazole, many efforts have been made to develop new sensitizers. In the U.S., Brown and others reported a new drug named SR-2508 (ethanidazole), which is now in phase II and III clinical trials.
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Radiosensitizers and Protectors
Cancer Investigation, 1984Florence Chu +4 more
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Radiosensitivity and genetic complexity
Journal of Theoretical Biology, 1965Abstract There is a strong correlation between the DNA content and the mean lethal dose in unicellular organisms. The constant of this inverse proportionality assumes four discrete values according to the genetic complexity of the organisms. The first level of radiosensitivity is that of viruses containing RNA or single-stranded DNA, the second is ...
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A need to redefine radiosensitivity
The British Journal of Radiology, 1982Radiotherapists use the terms radiosensitivity and radioresistance in their current work, but no clear definition or unifying concepts exist for these words. Since both denote the magnitude of the response of tissues or cells to radiation, they are relative terms. Absolute radiosensitivity or radioresistance does not exist.
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Catalytic radiosensitization: Insights from materials physicochemistry
Materials Today, 2022Ya Wang, Huilin Zhang, Yanyan Liu
exaly

