Results 61 to 70 of about 7,625 (228)

Photosensitizers and radiosensitizers in dermatology and oncology [PDF]

, 1979
ArticleThe original publication is available at http://www.samj.org.zaTwo therapeutic modalities are currently of great interest, namely photo- and radiosensitization.
Bruckner, V.
core  

Comparative analysis of radiosensitizers for K-RAS mutant rectal cancers. [PDF]

, 2013
Approximately 40% of rectal cancers harbor activating K-RAS mutations, and these mutations are associated with poor clinical response to chemoradiotherapy. We aimed to identify small molecule inhibitors (SMIs) that synergize with ionizing radiation (IR) (
Theodore S. Hong, Angela M. Krebs (496392), Laura B. Kleiman (496391), Kevin M. Haigis (135556), Angela M. Krebs, Laura B Kleiman, Stephen Y. Kim (496393), Angela M Krebs, Kevin M Haigis, Theodore S Hong, Kevin M. Haigis, Theodore S. Hong (496394), Stephen Y Kim, Stephen Y. Kim, Laura B. Kleiman, Kleiman Laura B., Kim Stephen Y., Hong Theodore S., Haigis Kevin M., Krebs Angela M.   +19 more
core   +1 more source

INFLUENCE OF METRONIDAZOLE ON BIOLOGICAL ACTION OF DOXORUBICIN

Исследования и практика в медицине, 2017
Purpose. Investigation of the effect of the Metronizatol on the biological effect of Doxirubicin.Materials and methods. The studies were performed in the CBA/Lac males and C57Bl/6 females mice grafted with melanoma B16 and mucinous ovarian cancer CaO‑1 ...
S. A. Yagubov, B. S. Amandzholov, F. V. Donenko, Yu. I. Dolzhikova, N. V. Malakhova   +4 more
doaj   +1 more source

Effect of Rosmarinic Acid and Ionizing Radiation on Glutathione in Melanoma B16F10 Cells: A Translational Opportunity

Antioxidants, 2020
To explain a paradoxical radiosensitizing effect of rosmarinic acid (RA) on the melanoma B16F10 cells, we analyzed the glutathione (GSH) intracellular production on this cell (traditionally considered radioresistant) in comparison with human prostate ...
Amparo Olivares, Miguel Alcaraz-Saura, Daniel Gyingiri Achel, Miguel Alcaraz   +3 more
doaj   +1 more source

Ligand‐Ratio–Tuned DNA Nanocarriers Overcome Bladder Barriers for Ultralow‐Dose Intravesical Therapy

Advanced Science, EarlyView.
A programmable DNA framework drug carrier coordinates barrier transport, tumor targeting, and drug delivery through ligand‐ratio engineering. Systematic exploration of the Sgc8/fluorocarbon design space reveals a nonlinear optimal balance between penetration and cellular engagement, translating multifunctional integration into durable bladder tumor ...
Dunfang Liu, Xiao Chen, Hongliang Bao, Qian Xia, Gang Huang, Yang Yang   +5 more
wiley   +1 more source

Radiosensitizers in hepatocellular carcinoma

, 2011
Most hepatocellular carcinoma (HCC) patients present with locally advanced disease with a risk of development of intrahepatic or extrahepatic metastases.
이익재, 성진실
core   +1 more source

From anthelmintic to neuro‐oncology: A systematic review of mebendazole repurposing for brain tumour therapy

British Journal of Clinical Pharmacology, EarlyView.
Abstract Aim Mebendazole (MBZ), a benzimidazole anthelmintic with established clinical use, has emerged as a repurposing candidate for primary brain tumours due to its multimodal anticancer actions and central nervous system penetrance. This systematic review synthesizes preclinical and clinical evidence evaluating MBZ's efficacy, mechanisms of action ...
Ciara B. Blum, Milli McMenamin, Tessa Khoo, John M. Edwin, Prathibha Jose, Liam A. O’Callaghan   +5 more
wiley   +1 more source

Ultrasmall BiOI Quantum Dots with Efficient Renal Clearance for Enhanced Radiotherapy of Cancer

Advanced Science, 2020
Emerging strategies involving nanomaterials with high‐atomic‐number elements have been widely developed for radiotherapy in recent years. However, the concern regarding their potential toxicity caused by long‐term body retention still limits their ...
Xin Wang, Zhao Guo, Chenyang Zhang, Shuang Zhu, Lele Li, Zhanjun Gu, Yuliang Zhao   +6 more
doaj   +1 more source

Correlation of the first reduction potential of selected radiosensitizers determined by cyclic voltammetry with theoretical calculations

, 2011
Radiosensitizers are drugs that make cancer cells more sensitive to radiation therapy. The cytotoxic properties of such compounds are due to the fact that in the cell these compounds undergo one-electron reduction to generate radical anions.
Miroslav Gál, Marta Ambrová, Viliam Kolivoška, Romana Sokolová, Ján Híveš   +4 more
core   +1 more source

Biocompatible cellulose nanocrystal-based Trojan horse enables targeted delivery of nano-Au radiosensitizers to triple negative breast cancer cells [PDF]

: A hybrid cellulose-based programmable nanoplatform for applications in precision radiation oncology is described. Here, sugar heads work as tumor targeting moieties and steer the precise delivery of radiosensitizers, i.e.
Mangini, Chiara, Berti, Debora, Andreozzi, Patrizia, Tobia, Chiara, Recchia, Sandro, Polito, Laura, di Gianvincenzo, Paolo, Severi, Mirko, Cazzoli, Riccardo, Garibaldi, Cristina, Cicchi, Stefano, Orecchia, Roberto, Ronca, Roberto, Biagiotti, Giacomo, Albini, Adriana, Minucci, Saverio, Vittorio, Orazio, Francesco, Mattii, Aresta, Giusi, Moya, Sergio E, Richichi, Barbara, Recchia S., Debora Berti, Mirko Severi, Patrizia Andreozzi, Riccardo Cazzoli, Orazio Vittorio, Orecchia R., Garibaldi C., Chiara Mangini, Sandro Recchia, Moya S. E., Berti D., Polito L., Stefano Cicchi, Barbara Richichi, Andreozzi P., Cicchi S., Laura Polito, Aresta G., Giacomo Biagiotti, Minucci S., Saverio Minucci, Roberto Orecchia, Ronca R., Giusi Aresta, Paolo di Gianvincenzo, Richichi B., Chiara Tobia, Roberto Ronca, Adriana Albini, Vittorio O., di Gianvincenzo P., Mangini C., Tobia C., Albini A., Francesco M., Cristina Garibaldi, Sergio E. Moya, Mattii Francesco, Cazzoli R., Biagiotti G., Severi M.   +62 more
core   +3 more sources