Effects of Radix Polygalae on Cognitive Decline and Depression in Estradiol Depletion Mouse Model of Menopause [PDF]
Current Issues in Molecular Biology, 2021 Postmenopausal syndrome refers to symptoms caused by the gradual decrease in female hormones after mid-40 years. As a target organ of estrogen, decrease in estrogen causes various changes in brain function such as a decrease in choline acetyltransferase ...
Heeok Hong, Sungho Maeng, Byung-il Kim
exaly +8 more sources
Protective Effects and Mechanism of Radix Polygalae Against Neurological Diseases as Well as Effective Substance [PDF]
Frontiers in Psychiatry, 2021 Radix Polygalae (also known as Yuanzhi in China) is the dried rhizome of Polygala tenuifolia Willd. or Polygala sibirica L., which is a famous Chinese herb and has been widely used for centuries in traditional medicines including expectorants, tonics ...
Xin-Min Liu
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Preclinical evidence of rapid-onset antidepressant-like effect in Radix Polygalae extract. [PDF]
PLoS ONE, 2014 Radix Polygalae (the root of Polygala tenuifolia) is a herb widely used in traditional Asian medicine that is thought to exert a variety of neuropsychiatric effects.
Im-Joon Shin +12 more
doaj +6 more sources
Illumination on “Reserving Phloem and Discarding Xylem” and Quality Evaluation of Radix Polygalae by Determining Oligosaccharide Esters, Saponins, and Xanthones [PDF]
Molecules, 2018 The root of Polygala tenuifolia Willd. or Polygala sibirica L. exhibits protective effects on the central nervous system and is frequently used to treat insomnia, amnesia, and other cognitive dysfunction. In our study, we studied nine bioactive compounds
Xin Chai, Yuefei Wang, Huijuan Yu
exaly +5 more sources
Reduced Consolidation, Reinstatement, and Renewal of Conditioned Fear Memory by Repetitive Treatment of Radix Polygalae in Mice [PDF]
Frontiers in Psychiatry, 2017 The therapeutic goal for the treatment of posttraumatic stress disorder (PTSD) is to promote extinction and to prevent the relapse of fearful memories. Research has identified pharmacological treatments that may regulate the formation and extinction of ...
Jung-Won Shin +8 more
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Study on the Dynamic Changes in Fungal Communities During the Storage of Polygalae Radix and the Antifungal Effects of Peppermint Essential Oil [PDF]
ToxinsPolygalae Radix, a traditional Chinese medicine for insomnia and memory disorders, is highly susceptible to fungal contamination and mycotoxin production (especially by Aspergillus flavus) during storage, compromising its safety and efficacy.
Hui Zhang +5 more
doaj +3 more sources
Revealing the sedative-hypnotic effect of the extracts of herb pair Semen Ziziphi spinosae and Radix Polygalae and related mechanisms through experiments and metabolomics approach [PDF]
BMC Complementary Medicine and Therapies, 2020 Background Semen Ziziphi spinosae and Radix Polygalae, two herbs commonly used together in Traditional Chinese Medicine for the treatment of insomnia and anxiety. The study aims to study the sedative-hypnotic effect of the active components of the herbal
Hong Luo +3 more
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3,6′-Disinapoyl Sucrose from Polygalae Radix Exerts Anti-Aging Effects via Modification of Telomeres, SIRT1/p53/p21 Pathway, Oxidative Stress and Autophagy [PDF]
AntioxidantsTraditional Chinese medicine plays an important role in human health, but due to the complexity of its active fraction, its therapeutic mechanism still needs further clarification.
Jianhong Wang +6 more
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Exploring the Role of Radix Polygalae in Melanogenesis Related to Vitiligo: A Network Pharmacology Analysis with in vitro Validation [PDF]
Clinical, Cosmetic and Investigational DermatologyLu Zhu,1,* Yixuan Liang,1,2,* Ling Jiang,1 Chuhan Fu,1 Xixia Dai,1 Haoran Guo,1 Qinghai Zeng,1 Shuanghai Hu,3 Jing Chen1 1Department of Dermatology, The Third Xiangya Hospital of Central South University, Changsha, Hunan, People’s ...
Zhu L +8 more
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Exploring the patterns in traditional Chinese medicine for bipolar disorder: a data-driven network approach [PDF]
Frontiers in PharmacologyAim of the studyTraditional Chinese Medicine offers a holistic approach that could provide complementary benefits for bipolar disorder treatment. However, the clinical cases in Traditional Chinese Medicine are highly dispersed, creating challenges for ...
Zhenshan Sun +8 more
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