Results 171 to 180 of about 4,270,323 (214)

A sensitive interactome-based approach to characterize drug activity in living human cells. [PDF]

J Biol Chem
Kundlacz C, Forcet C, Sleiman NH, Vonau S, Marmigère F, Gillet B, Hughes S, Gilquin L, Duplus H, Dumont A, Yvert G, Bleicher F, Gautier A, Coste I, Renno T, Merabet S.   +15 more
europepmc   +1 more source

Molecular mechanism of KRAS binding to BRAF and its regulation by the BRAF-specific region. [PDF]

Structure
Bonsor DA, Sandin Lawrence SI, Tran TH, Swain M, Dharmaiah S, Mehalko J, Messing SA, Nissley DV, McCormick F, Stephen AG, Simanshu DK.   +10 more
europepmc   +1 more source

Discovery of Cyclic Peptides Targeting the BRAF Dimer Interface as Dual Inhibitors. [PDF]

ACS Pharmacol Transl Sci
Zhang K, Zhang WW, Dong P, Wang G, Gai C, Chai X, Zhuo X, Xiao Y, Hu K, Li J, Zhang PC, Zhao Q, Zou Y.   +12 more
europepmc   +1 more source

Recent Progress in Urea-Containing Compounds as Tyrosine Kinase Inhibitors. [PDF]

Chem Biodivers
Sroor FM.
europepmc   +1 more source

Monovalent Nondegrading Molecular Glues: An Updated Overview of Emerging Mechanisms and Therapeutic Development. [PDF]

Pharmaceuticals (Basel)
Li L, Li J, Yang L, Zhou J, Ma Y.
europepmc   +1 more source

Healthy Participant Versus Patient Selection for Clinical Pharmacology Studies in Small‐Molecule Oncology Drug Development

Clinical and Translational Science, Volume 19, Issue 11, November 2026.
Paridhi Gupta, Zheyi Hu, Li Zhu, Lora Hamuro   +3 more
wiley   +1 more source

Therapeutic Resistance in Melanoma: Molecular Mechanisms and Emerging Pharmaceutical Strategies. [PDF]

Pharmaceuticals (Basel)
Moussallem N, Awada A, El Darzi R, Tarhini A, Khaled A, Ashy C, Nasr W, El Masri A, Saad G, Itani M, Rizkallah J, Charbel N, Hatahet Z, Saade D, Abou Rahal J, Kreidieh F.   +15 more
europepmc   +1 more source

Common reduction of the Raf kinase inhibitory protein in clear cell renal cell carcinoma. [PDF]

Oncotarget, 2014
Hill B, De Melo J, Yan J, Kapoor A, He L, Cutz JC, Feng X, Bakhtyar N, Tang D.   +8 more
europepmc   +1 more source

Prognostic value of phosphorylated Raf kinase inhibitory protein at serine 153 and its predictive effect on the clinical response to radiotherapy in nasopharyngeal carcinoma. [PDF]

Radiat Oncol, 2016
Li S, Liu T, Mo W, Hou Q, Zhou Y, Liu M, He Z, Liu Z, Chen Q, Wang H, Guo X, Xia W, Zeng M, Zhao H.   +13 more
europepmc   +1 more source

Comparison of the Effects of Sorafenib and Stem Cell Secretome on HepG2 Cancer Cells with Respect to the Ras/Raf/MEK/ERK Pathway. [PDF]

J Clin Med
Gładyś A, Skubis-Sikora A, Sikora B, Pogoda-Mieszczak K, Wieczorek P, Bogunia E, Czekaj P.   +6 more
europepmc   +1 more source